克服适应功能的学习先决条件中的挑战:Rett综合征年轻女孩的远程康复。

IF 3 3区 医学 Q2 HEALTH CARE SCIENCES & SERVICES
Rosa Angela Fabio, Samantha Giannatiempo, Michela Perina
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引用次数: 0

摘要

背景/目的:Rett综合征(RTT)是一种罕见的影响女孩的神经发育障碍,其特征是严重的运动和认知障碍,失去有目的的手使用和沟通困难。患有RTT的儿童,尤其是5至9岁的儿童,往往难以发展适应功能所需的基本技能,如眼神交流、物体追踪、功能性手势、轮流和基本沟通。这些能力对认知、社交和运动发展至关重要,有助于在日常生活中获得更大的自主权。本研究旨在探索结构化远程康复计划的可行性,并对其对患有RTT的年轻女孩的潜在效用进行初步观察,解决使这些人参与基于视频的互动培训的假定挑战。方法:干预包括30次远程授课(每次持续90分钟),分别在基线(A)、5周后(B1)和10周后(B2)进行评估。定量结果测量侧重于目光接触、物体跟踪、功能性手势、社交参与和对视觉刺激的反应性的变化。结果:研究结果表明,该方案是可行的,耐受性良好。在所有测量领域都观察到改善,参与者在整个干预过程中表现出高水平的参与和参与。虽然这些结果是初步的,但它们表明交互式数字格式可能有希望支持RTT儿童的基础学习过程。结论:本研究提供了初步证据,证明远程康复是一种可行的方法,可以让年轻女孩参与RTT并支持适应技能的发展。这些发现可能为未来的研究和对照研究的设计提供信息,以评估技术辅助干预在这一人群中的效果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Overcoming Challenges in Learning Prerequisites for Adaptive Functioning: Tele-Rehabilitation for Young Girls with Rett Syndrome.

Background/Objectives: Rett Syndrome (RTT) is a rare neurodevelopmental disorder that affects girls and is characterized by severe motor and cognitive impairments, the loss of purposeful hand use, and communication difficulties. Children with RTT, especially those aged 5 to 9 years, often struggle to develop the foundational skills necessary for adaptive functioning, such as eye contact, object tracking, functional gestures, turn-taking, and basic communication. These abilities are essential for cognitive, social, and motor development and contribute to greater autonomy in daily life. This study aimed to explore the feasibility of a structured telerehabilitation program and to provide preliminary observations of its potential utility for young girls with RTT, addressing the presumed challenge of engaging this population in video-based interactive training. Methods: The intervention consisted of 30 remotely delivered sessions (each lasting 90 min), with assessments at baseline (A), after 5 weeks (B1), and after 10 weeks (B2). Quantitative outcome measures focused on changes in eye contact, object tracking, functional gestures, social engagement, and responsiveness to visual stimulus. Results: The findings indicate that the program was feasible and well-tolerated. Improvements were observed across all measured domains, and participants showed high levels of engagement and participation throughout the intervention. While these results are preliminary, they suggest that interactive digital formats may be promising for supporting foundational learning processes in children with RTT. Conclusions: This study provides initial evidence that telerehabilitation is a feasible approach for engaging young girls with RTT and supporting adaptive skill development. These findings may inform future research and the design of controlled studies to evaluate the efficacy of technology-assisted interventions in this population.

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来源期刊
Journal of Personalized Medicine
Journal of Personalized Medicine Medicine-Medicine (miscellaneous)
CiteScore
4.10
自引率
0.00%
发文量
1878
审稿时长
11 weeks
期刊介绍: Journal of Personalized Medicine (JPM; ISSN 2075-4426) is an international, open access journal aimed at bringing all aspects of personalized medicine to one platform. JPM publishes cutting edge, innovative preclinical and translational scientific research and technologies related to personalized medicine (e.g., pharmacogenomics/proteomics, systems biology). JPM recognizes that personalized medicine—the assessment of genetic, environmental and host factors that cause variability of individuals—is a challenging, transdisciplinary topic that requires discussions from a range of experts. For a comprehensive perspective of personalized medicine, JPM aims to integrate expertise from the molecular and translational sciences, therapeutics and diagnostics, as well as discussions of regulatory, social, ethical and policy aspects. We provide a forum to bring together academic and clinical researchers, biotechnology, diagnostic and pharmaceutical companies, health professionals, regulatory and ethical experts, and government and regulatory authorities.
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