不可逆电穿孔治疗心房颤动导管消融的生物物理及临床效果。

IF 2.3 4区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Journal of Cardiovascular Development and Disease Pub Date : 2025-06-07 DOI:10.3390/jcdd12060218

Anna-Sophie Eberl, Gernot Plank, Martin Manninger, Ursula Rohrer, Laura Stix, Stefan Kurath-Koller, Andreas Zirlik, Daniel Scherr

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引用次数: 0

摘要

了解电穿孔的生物物理学——脉冲电场实现组织消融的机制——对于推进这一新兴技术至关重要。在这篇综述中，我们总结了过去几年的主要出版物，以提供当前知识和未来展望的概述。我们从细胞、物理和技术层面讨论了PFA的基本原理，以及它潜在的好处和局限性。更深入地了解这些生物物理机制和产生持久病变所需的参数可能有助于改善临床结果并推动未来的创新。

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Biophysics and Clinical Effectiveness of Irreversible Electroporation for Catheter Ablation of Atrial Fibrillation.

Understanding the biophysics of electroporation-the mechanism by which pulsed electric fields achieve tissue ablation-is essential for advancing this emerging technology. In this review, we summarize key publications from past years to provide an overview of current knowledge and future perspectives. We discuss the fundamental principles of PFA at the cellular, physical, and technical levels, along with its potential benefits and limitations. A deeper understanding of these biophysical mechanisms and the parameters required to create durable lesions may contribute to improved clinical outcomes and drive future innovation.

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来源期刊

Journal of Cardiovascular Development and Disease CARDIAC & CARDIOVASCULAR SYSTEMS-

CiteScore

2.60

自引率

12.50%

发文量

381