{"title":"双侧原发性乳腺癌:导管原位癌与浸润性导管癌同步诊断与治疗一例。","authors":"Yan Wang, Yong Chen, Bo Zhang, Xianfu Liu","doi":"10.12968/hmed.2024.1013","DOIUrl":null,"url":null,"abstract":"<p><p><b>Aims/Background</b> Bilateral breast cancer (BBC) is an uncommon subtype of breast cancer which occurs either synchronously or metachronously. Synchronous BBC with distinct histological types in the left and right breasts is particularly rare. <b>Case Presentation</b> This report presents a case of a 57-year-old female patient diagnosed with bilateral primary breast cancer, characterized by ductal carcinoma <i>in situ</i> (DCIS) in one breast and invasive ductal carcinoma (IDC) in the other. The patient initially sought medical attention due to a palpable mass and pain in her left breast, leading to a diagnosis confirmed through imaging studies and biopsy. The patient was treated with three cycles of neoadjuvant therapy, followed by a modified radical mastectomy on the left breast and a lumpectomy on the right breast. Postoperatively, the patient received endocrine therapy and radiotherapy, with no evidence of recurrence observed to date. <b>Conclusion</b> Further research and clinical advancements are necessary to optimize treatment and care strategies for patients with bilateral breast cancer, ensuring that their unique therapeutic needs are effectively addressed.</p>","PeriodicalId":9256,"journal":{"name":"British journal of hospital medicine","volume":"86 6","pages":"1-9"},"PeriodicalIF":1.8000,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Bilateral Primary Breast Cancer: A Case of Synchronous Diagnosis and Management of Ductal Carcinoma <i>In Situ</i> and Invasive Ductal Carcinoma.\",\"authors\":\"Yan Wang, Yong Chen, Bo Zhang, Xianfu Liu\",\"doi\":\"10.12968/hmed.2024.1013\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p><b>Aims/Background</b> Bilateral breast cancer (BBC) is an uncommon subtype of breast cancer which occurs either synchronously or metachronously. Synchronous BBC with distinct histological types in the left and right breasts is particularly rare. <b>Case Presentation</b> This report presents a case of a 57-year-old female patient diagnosed with bilateral primary breast cancer, characterized by ductal carcinoma <i>in situ</i> (DCIS) in one breast and invasive ductal carcinoma (IDC) in the other. The patient initially sought medical attention due to a palpable mass and pain in her left breast, leading to a diagnosis confirmed through imaging studies and biopsy. The patient was treated with three cycles of neoadjuvant therapy, followed by a modified radical mastectomy on the left breast and a lumpectomy on the right breast. Postoperatively, the patient received endocrine therapy and radiotherapy, with no evidence of recurrence observed to date. <b>Conclusion</b> Further research and clinical advancements are necessary to optimize treatment and care strategies for patients with bilateral breast cancer, ensuring that their unique therapeutic needs are effectively addressed.</p>\",\"PeriodicalId\":9256,\"journal\":{\"name\":\"British journal of hospital medicine\",\"volume\":\"86 6\",\"pages\":\"1-9\"},\"PeriodicalIF\":1.8000,\"publicationDate\":\"2025-06-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"British journal of hospital medicine\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.12968/hmed.2024.1013\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/6/24 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q3\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"British journal of hospital medicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.12968/hmed.2024.1013","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/6/24 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
Bilateral Primary Breast Cancer: A Case of Synchronous Diagnosis and Management of Ductal Carcinoma In Situ and Invasive Ductal Carcinoma.
Aims/Background Bilateral breast cancer (BBC) is an uncommon subtype of breast cancer which occurs either synchronously or metachronously. Synchronous BBC with distinct histological types in the left and right breasts is particularly rare. Case Presentation This report presents a case of a 57-year-old female patient diagnosed with bilateral primary breast cancer, characterized by ductal carcinoma in situ (DCIS) in one breast and invasive ductal carcinoma (IDC) in the other. The patient initially sought medical attention due to a palpable mass and pain in her left breast, leading to a diagnosis confirmed through imaging studies and biopsy. The patient was treated with three cycles of neoadjuvant therapy, followed by a modified radical mastectomy on the left breast and a lumpectomy on the right breast. Postoperatively, the patient received endocrine therapy and radiotherapy, with no evidence of recurrence observed to date. Conclusion Further research and clinical advancements are necessary to optimize treatment and care strategies for patients with bilateral breast cancer, ensuring that their unique therapeutic needs are effectively addressed.
期刊介绍:
British Journal of Hospital Medicine was established in 1966, and is still true to its origins: a monthly, peer-reviewed, multidisciplinary review journal for hospital doctors and doctors in training.
The journal publishes an authoritative mix of clinical reviews, education and training updates, quality improvement projects and case reports, and book reviews from recognized leaders in the profession. The Core Training for Doctors section provides clinical information in an easily accessible format for doctors in training.
British Journal of Hospital Medicine is an invaluable resource for hospital doctors at all stages of their career.
The journal is indexed on Medline, CINAHL, the Sociedad Iberoamericana de Información Científica and Scopus.