{"title":"蕈样真菌病如何影响生活质量？蕈样真菌病与牛皮癣患者皮肤科生活质量指数的比较评价。","authors":"Funda Tamer, Yagmur Aypek, Esra Adisen","doi":"10.1080/08998280.2025.2500853","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Mycosis fungoides is a chronic cutaneous lymphoma that requires close follow up due to frequent recurrences. Although quality of life has an important role in cancer management, it is generally not evaluated in patients with mycosis fungoides. The Dermatology Life Quality Index (DLQI) questionnaire is a validated skin-specific quality of life index, with answers scored on a scale from 0 to 30. Higher scores are considered as demonstrating a high impact on quality of life. Herein, we compared DLQI scores in patients with mycosis fungoides and psoriasis.</p><p><strong>Methods: </strong>Medical records of patients admitted to the dermatology outpatient clinic between March 2023 and May 2023 were reviewed retrospectively. Afterward, the patients were contacted by phone to answer the questions on the DLQI.</p><p><strong>Results: </strong>This study included a total of 110 patients, 60 with psoriasis and 50 with mycosis fungoides. The median DLQI score was 4 (standard deviation [SD] 8) (range 0-24) in psoriasis patients and 1 (SD 4) (range 0-19) in patients with mycosis fungoides (<i>P</i> = 0.03). Psoriasis affected patients' quality of life more than mycosis fungoides in terms of symptoms and feelings (<i>P</i> = 0.03) and work or school (<i>P</i> = 0.04). However, the median DLQI was similar in patients with mycosis fungoides and psoriasis in terms of daily activities (<i>P</i> = 0.10), leisure (<i>P</i> = 0.28), personal relationships (<i>P</i> = 0.21), and treatment (<i>P</i> = 0.23). Moreover, skin lesions such as plaque and tumor, lesions on extremities, lymph node involvement, itching, pain, and systemic treatment were associated with high DLQI scores in patients with mycosis fungoides.</p><p><strong>Conclusion: </strong>Since various factors such as lesion type, lesion location, symptoms, and treatment significantly affect the DLQI, and DLQI subgroups were affected similarly to patients with psoriasis, we suggest considering DLQI scores when determining the most appropriate treatment option in patients with mycosis fungoides.</p>","PeriodicalId":8828,"journal":{"name":"Baylor University Medical Center Proceedings","volume":"38 4","pages":"427-433"},"PeriodicalIF":0.0000,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12184161/pdf/","citationCount":"0","resultStr":"{\"title\":\"How does mycosis fungoides affect quality of life? Comparative evaluation of the Dermatology Life Quality Index in patients with mycosis fungoides and psoriasis.\",\"authors\":\"Funda Tamer, Yagmur Aypek, Esra Adisen\",\"doi\":\"10.1080/08998280.2025.2500853\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Mycosis fungoides is a chronic cutaneous lymphoma that requires close follow up due to frequent recurrences. Although quality of life has an important role in cancer management, it is generally not evaluated in patients with mycosis fungoides. The Dermatology Life Quality Index (DLQI) questionnaire is a validated skin-specific quality of life index, with answers scored on a scale from 0 to 30. Higher scores are considered as demonstrating a high impact on quality of life. Herein, we compared DLQI scores in patients with mycosis fungoides and psoriasis.</p><p><strong>Methods: </strong>Medical records of patients admitted to the dermatology outpatient clinic between March 2023 and May 2023 were reviewed retrospectively. Afterward, the patients were contacted by phone to answer the questions on the DLQI.</p><p><strong>Results: </strong>This study included a total of 110 patients, 60 with psoriasis and 50 with mycosis fungoides. The median DLQI score was 4 (standard deviation [SD] 8) (range 0-24) in psoriasis patients and 1 (SD 4) (range 0-19) in patients with mycosis fungoides (<i>P</i> = 0.03). Psoriasis affected patients' quality of life more than mycosis fungoides in terms of symptoms and feelings (<i>P</i> = 0.03) and work or school (<i>P</i> = 0.04). However, the median DLQI was similar in patients with mycosis fungoides and psoriasis in terms of daily activities (<i>P</i> = 0.10), leisure (<i>P</i> = 0.28), personal relationships (<i>P</i> = 0.21), and treatment (<i>P</i> = 0.23). Moreover, skin lesions such as plaque and tumor, lesions on extremities, lymph node involvement, itching, pain, and systemic treatment were associated with high DLQI scores in patients with mycosis fungoides.</p><p><strong>Conclusion: </strong>Since various factors such as lesion type, lesion location, symptoms, and treatment significantly affect the DLQI, and DLQI subgroups were affected similarly to patients with psoriasis, we suggest considering DLQI scores when determining the most appropriate treatment option in patients with mycosis fungoides.</p>\",\"PeriodicalId\":8828,\"journal\":{\"name\":\"Baylor University Medical Center Proceedings\",\"volume\":\"38 4\",\"pages\":\"427-433\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-05-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12184161/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Baylor University Medical Center Proceedings\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1080/08998280.2025.2500853\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q3\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Baylor University Medical Center Proceedings","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1080/08998280.2025.2500853","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
How does mycosis fungoides affect quality of life? Comparative evaluation of the Dermatology Life Quality Index in patients with mycosis fungoides and psoriasis.
Background: Mycosis fungoides is a chronic cutaneous lymphoma that requires close follow up due to frequent recurrences. Although quality of life has an important role in cancer management, it is generally not evaluated in patients with mycosis fungoides. The Dermatology Life Quality Index (DLQI) questionnaire is a validated skin-specific quality of life index, with answers scored on a scale from 0 to 30. Higher scores are considered as demonstrating a high impact on quality of life. Herein, we compared DLQI scores in patients with mycosis fungoides and psoriasis.
Methods: Medical records of patients admitted to the dermatology outpatient clinic between March 2023 and May 2023 were reviewed retrospectively. Afterward, the patients were contacted by phone to answer the questions on the DLQI.
Results: This study included a total of 110 patients, 60 with psoriasis and 50 with mycosis fungoides. The median DLQI score was 4 (standard deviation [SD] 8) (range 0-24) in psoriasis patients and 1 (SD 4) (range 0-19) in patients with mycosis fungoides (P = 0.03). Psoriasis affected patients' quality of life more than mycosis fungoides in terms of symptoms and feelings (P = 0.03) and work or school (P = 0.04). However, the median DLQI was similar in patients with mycosis fungoides and psoriasis in terms of daily activities (P = 0.10), leisure (P = 0.28), personal relationships (P = 0.21), and treatment (P = 0.23). Moreover, skin lesions such as plaque and tumor, lesions on extremities, lymph node involvement, itching, pain, and systemic treatment were associated with high DLQI scores in patients with mycosis fungoides.
Conclusion: Since various factors such as lesion type, lesion location, symptoms, and treatment significantly affect the DLQI, and DLQI subgroups were affected similarly to patients with psoriasis, we suggest considering DLQI scores when determining the most appropriate treatment option in patients with mycosis fungoides.
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