27 - 45岁成人的HPV疫苗接种知识和决策：一项大型在线调查

IF 1.7 4区医学 Q2 OTORHINOLARYNGOLOGY

Laryngoscope Investigative Otolaryngology Pub Date : 2025-06-25 DOI:10.1002/lio2.70182

Matthew E. Lin, Oluwatobiloba Ayo-Ajibola, Jun Yun, Tyler J. Gallagher, Carlos X. Castellanos, Jonathan D. West, Ian Kim, Sophia Chen, Niels C. Kokot, Tamara N. Chambers

{"title":"27 - 45岁成人的HPV疫苗接种知识和决策：一项大型在线调查","authors":"Matthew E. Lin, Oluwatobiloba Ayo-Ajibola, Jun Yun, Tyler J. Gallagher, Carlos X. Castellanos, Jonathan D. West, Ian Kim, Sophia Chen, Niels C. Kokot, Tamara N. Chambers","doi":"10.1002/lio2.70182","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Objective</h3>\n \n <p>Understand knowledge and barriers to human papillomavirus (HPV) vaccination among United States (US) adults, comparing adults in the original age cohort of 18–26 years to those in the expanded 27–45-yearyear-old cohort.</p>\n </section>\n \n <section>\n \n <h3> Methods</h3>\n \n <p>A cross-sectional survey was administered to US adults recruited through social media. Descriptive statistics characterized the data. Multivariate logistic regression identified factors associated with vaccination.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>Among 1735 respondents, the majority were in the 27–45 age group (936, 53.94%). The 27–45-year group exhibited more knowledge of HPV's link to head and neck cancer and vaccine protection but expressed less concern about HPV infection (all <i>p</i> < 0.05). Key motivators for the history of vaccination in the 27–45 year cohort included vaccine effectiveness (48.65%) and prior knowledge (42.44%). Self-vaccination rates were comparable across age groups (18–26: 70.62% vs. 27–45: 68.07%, <i>p</i> = 0.256). Older adults were less likely to vaccinate dependents (68.57% vs. 75.00%, <i>p</i> < 0.001) despite higher interest (<i>p</i> < 0.001). Main barriers for unvaccinated 27–45 year old adults included scheduling issues, insurance coverage, and lack of concern for HPV infection (all <i>p</i> < 0.05). Among individuals aged 27 to 45, multivariate logistic regression analysis revealed significantly higher odds of vaccination in those from the Western US (compared to Northeast/Midwest) (OR 3.15, 95% CI: [1.84, 5.39]) and personal history of head and neck cancer (3.01, [1.78–5.09]).</p>\n </section>\n \n <section>\n \n <h3> Conclusion</h3>\n \n <p>Most respondents understand HPV risks and are vaccinated. Interventions directed towards education about vaccine safety, the hazards of HPV, and improving access may increase vaccination.</p>\n </section>\n \n <section>\n \n <h3> Level of Evidence</h3>\n \n <p>IV.</p>\n </section>\n </div>","PeriodicalId":48529,"journal":{"name":"Laryngoscope Investigative Otolaryngology","volume":"10 3","pages":""},"PeriodicalIF":1.7000,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/lio2.70182","citationCount":"0","resultStr":"{\"title\":\"HPV Vaccination Knowledge and Decision-Making Among Adults 27 to 45 Years: A Large Online Survey\",\"authors\":\"Matthew E. Lin, Oluwatobiloba Ayo-Ajibola, Jun Yun, Tyler J. Gallagher, Carlos X. Castellanos, Jonathan D. West, Ian Kim, Sophia Chen, Niels C. Kokot, Tamara N. Chambers\",\"doi\":\"10.1002/lio2.70182\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n \\n \\n <section>\\n \\n <h3> Objective</h3>\\n \\n <p>Understand knowledge and barriers to human papillomavirus (HPV) vaccination among United States (US) adults, comparing adults in the original age cohort of 18–26 years to those in the expanded 27–45-yearyear-old cohort.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Methods</h3>\\n \\n <p>A cross-sectional survey was administered to US adults recruited through social media. Descriptive statistics characterized the data. Multivariate logistic regression identified factors associated with vaccination.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Results</h3>\\n \\n <p>Among 1735 respondents, the majority were in the 27–45 age group (936, 53.94%). The 27–45-year group exhibited more knowledge of HPV's link to head and neck cancer and vaccine protection but expressed less concern about HPV infection (all <i>p</i> < 0.05). Key motivators for the history of vaccination in the 27–45 year cohort included vaccine effectiveness (48.65%) and prior knowledge (42.44%). Self-vaccination rates were comparable across age groups (18–26: 70.62% vs. 27–45: 68.07%, <i>p</i> = 0.256). Older adults were less likely to vaccinate dependents (68.57% vs. 75.00%, <i>p</i> < 0.001) despite higher interest (<i>p</i> < 0.001). Main barriers for unvaccinated 27–45 year old adults included scheduling issues, insurance coverage, and lack of concern for HPV infection (all <i>p</i> < 0.05). Among individuals aged 27 to 45, multivariate logistic regression analysis revealed significantly higher odds of vaccination in those from the Western US (compared to Northeast/Midwest) (OR 3.15, 95% CI: [1.84, 5.39]) and personal history of head and neck cancer (3.01, [1.78–5.09]).</p>\\n </section>\\n \\n <section>\\n \\n <h3> Conclusion</h3>\\n \\n <p>Most respondents understand HPV risks and are vaccinated. Interventions directed towards education about vaccine safety, the hazards of HPV, and improving access may increase vaccination.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Level of Evidence</h3>\\n \\n <p>IV.</p>\\n </section>\\n </div>\",\"PeriodicalId\":48529,\"journal\":{\"name\":\"Laryngoscope Investigative Otolaryngology\",\"volume\":\"10 3\",\"pages\":\"\"},\"PeriodicalIF\":1.7000,\"publicationDate\":\"2025-06-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1002/lio2.70182\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Laryngoscope Investigative Otolaryngology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/lio2.70182\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"OTORHINOLARYNGOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Laryngoscope Investigative Otolaryngology","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/lio2.70182","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"OTORHINOLARYNGOLOGY","Score":null,"Total":0}

引用次数: 0

摘要

目的了解美国成年人对人乳头瘤病毒（HPV）疫苗接种的知识和障碍，比较18-26岁原始年龄队列和27 - 45岁扩展队列的成年人。方法对通过社交媒体招募的美国成年人进行横断面调查。描述性统计描述了数据的特征。多变量logistic回归确定了与疫苗接种相关的因素。结果1735名调查对象中，27 ~ 45岁年龄组居多（936人，占53.94%）；27 - 45岁年龄组对HPV与头颈癌和疫苗保护的关系有更多的了解，但对HPV感染的关注较少（p < 0.05）。27-45岁队列中疫苗接种史的主要激励因素包括疫苗有效性（48.65%）和先验知识（42.44%）。各年龄组的自我疫苗接种率具有可比性（18-26岁：70.62% vs. 27-45岁：68.07%,p = 0.256）。老年人不太可能给家属接种疫苗（68.57%对75.00%,p < 0.001），尽管兴趣较高（p < 0.001）。未接种疫苗的27-45岁成年人的主要障碍包括日程安排问题、保险覆盖范围和缺乏对HPV感染的关注（均p <； 0.05）。在27岁至45岁的人群中，多因素logistic回归分析显示，来自美国西部（与东北/中西部相比）的人群接种疫苗的几率（OR 3.15, 95% CI:[1.84, 5.39]）和头颈癌个人病史（3.01,[1.78-5.09]）显著更高。结论大多数应答者了解HPV的危险性并接种了疫苗。针对疫苗安全、人乳头瘤病毒危害和改善获取途径的教育的干预措施可能会增加疫苗接种。证据级别IV。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

HPV Vaccination Knowledge and Decision-Making Among Adults 27 to 45 Years: A Large Online Survey

查看原文本刊更多论文

HPV Vaccination Knowledge and Decision-Making Among Adults 27 to 45 Years: A Large Online Survey

Objective

Understand knowledge and barriers to human papillomavirus (HPV) vaccination among United States (US) adults, comparing adults in the original age cohort of 18–26 years to those in the expanded 27–45-yearyear-old cohort.

Methods

A cross-sectional survey was administered to US adults recruited through social media. Descriptive statistics characterized the data. Multivariate logistic regression identified factors associated with vaccination.

Results

Among 1735 respondents, the majority were in the 27–45 age group (936, 53.94%). The 27–45-year group exhibited more knowledge of HPV's link to head and neck cancer and vaccine protection but expressed less concern about HPV infection (all p < 0.05). Key motivators for the history of vaccination in the 27–45 year cohort included vaccine effectiveness (48.65%) and prior knowledge (42.44%). Self-vaccination rates were comparable across age groups (18–26: 70.62% vs. 27–45: 68.07%, p = 0.256). Older adults were less likely to vaccinate dependents (68.57% vs. 75.00%, p < 0.001) despite higher interest (p < 0.001). Main barriers for unvaccinated 27–45 year old adults included scheduling issues, insurance coverage, and lack of concern for HPV infection (all p < 0.05). Among individuals aged 27 to 45, multivariate logistic regression analysis revealed significantly higher odds of vaccination in those from the Western US (compared to Northeast/Midwest) (OR 3.15, 95% CI: [1.84, 5.39]) and personal history of head and neck cancer (3.01, [1.78–5.09]).

Conclusion

Most respondents understand HPV risks and are vaccinated. Interventions directed towards education about vaccine safety, the hazards of HPV, and improving access may increase vaccination.