基于双层seqFISH+的核结构空间多组学研究

IF 39.1 1区生物学 Q1 GENETICS & HEREDITY

Nature Reviews Genetics Pub Date : 2025-06-25 DOI:10.1038/s41576-025-00868-5

Yodai Takei

引用次数: 0

摘要

在这篇贸易工具文章中，Yodai Takei介绍了两层seqFISH+，这是一种成像方法，使用一种新颖的条形码策略，在单细胞分辨率下同时分析染色质组织，转录组和亚核结构。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Spatial multi-omics of nuclear architecture with two-layer seqFISH+

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Spatial multi-omics of nuclear architecture with two-layer seqFISH+

In this Tools of the Trade article, Yodai Takei presents two-layer seqFISH+, an imaging method that uses a novel barcoding strategy to simultaneously profile chromatin organization, the transcriptome and subnuclear structures at single-cell resolution.

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来源期刊

Nature Reviews Genetics 生物-遗传学

CiteScore

57.40

自引率

0.50%

发文量

113

审稿时长

6-12 weeks

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