[基于微生物-肠-脑轴的针刺作用机制研究进展]。

Q3 Medicine
Min Xing, Li-Na Qiao, Hong-Ye Wan, Yong-Sheng Yang
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引用次数: 0

摘要

微生物-肠-脑轴是指肠道微生物群与中枢神经系统通过神经、免疫、内分泌和代谢等途径双向连接的通路,其功能障碍是许多疾病的关键因素。针刺通过调节肠道菌群的结构和代谢状态,改善肠道微环境,恢复肠粘膜屏障和血脑屏障的稳定性,刺激迷走神经,减少炎症,调节神经递质,调节微生物-肠-脑轴,从而治疗神经系统疾病、精神疾病、消化系统疾病和代谢性疾病。考虑到最新的研究趋势和前沿技术,未来的研究应深化针刺对肠道微生物群结构和组成调节生理通路的机制,并对其进行整体阐述。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Research progress on the mechanism of acupuncture based on microbiota-gut-brain axis].

Microbiota-gut-brain axis refers to a bidirectional pathway between gut microbiota and the central nervous systems via neural, immune, endocrine and metabolic pathways, and its dysfunction is the crucial factor implicated in many diseases. Acupuncture adjusts the microbiota-gut-brain axis through regulating the structure and metabolic state of gut microbiota, improving the intestinal microenvironment, restoring the stability of intestinal mucosal barrier and blood-brain barrier, stimulating vagus nerve, reducing inflammation and modulating neurotransmitters, so that nervous system diseases, mental diseases, digestive system diseases and metabolic diseases can be treated. With the latest research trends and the cutting-edge technologies considered, the studies in the future should deepen the mechanism of acupuncture on the physiological pathway for modulating the structure and composition of gut microbiota as well as its holistic elaboration.

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来源期刊
针刺研究
针刺研究 Medicine-Medicine (all)
CiteScore
1.30
自引率
0.00%
发文量
0
期刊介绍: Acupuncture Research was founded in 1976. It is an acupuncture academic journal supervised by the State Administration of Traditional Chinese Medicine, co-sponsored by the Institute of Acupuncture of the China Academy of Chinese Medical Sciences and the Chinese Acupuncture Association. This journal is characterized by "basic experimental research as the main focus, taking into account clinical research and reporting". It is the only journal in my country that focuses on reporting the mechanism of action of acupuncture. The journal has been changed to a monthly journal since 2018, published on the 25th of each month, and printed in full color. The manuscript acceptance rate is about 10%, and provincial and above funded projects account for about 80% of the total published papers, reflecting the latest scientific research results in the acupuncture field and has a high academic level. Main columns: mechanism discussion, clinical research, acupuncture anesthesia, meridians and acupoints, theoretical discussion, ideas and methods, literature research, etc.
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