内镜切除:治疗食管胃肠道间质瘤的新方法。

IF 1.8 Q4 GASTROENTEROLOGY & HEPATOLOGY
Arvind Mukundan, Devansh Gupta, Riya Karmakar, Hsiang-Chen Wang
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引用次数: 0

摘要

在这封信中,对Xu等人的文章进行了评论。胃肠道瘘瘤(gist)是一种罕见的肿瘤,通常起源于胃(60%-70%)和小肠(30%-40%)。由于病理和临床资料有限,治疗过程非常复杂,难以诊断,尤其是食道间质瘤。内镜切除(ER)是一种从食道和消化系统切除肿瘤的微创方法,不需要开放手术,对于非常小和低风险的GIST尤其成功。回顾性分析2012 - 2023年间32例ER治疗患者的临床病理特征、治疗效果及远期预后。结果表明,96.9%的病例实现了整体切除,R0切除率为75%,肿瘤中位大小约为2.12 cm。术后并发症如胸腔积液、内镜下粘膜剥离后电凝综合征约占25%,经保守治疗后消失。GIST的复发率约为9.4%,主要发生在高危病例中。ER手术成功率高、复发率低、生存效果好,可用于低危食管间质瘤的治疗,具有较好的预后价值。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Endoscopic resection: A novel approach for treating oesophageal gastrointestinal stromal tumours.

In this letter, a commentary on the article by Xu et al has been provided. Gastrointestinal stomal tumours (GISTs) are rare tumours that originate commonly in stomach (60%-70%) and small intestine (30%-40%). The course of treatment especially oesophageal GIST is very complex and hard to diagnose because of limited availability of pathological and clinical data. Endoscopic resection (ER) is a minimally invasive approach for removing tumours from the oesophagus and digestive system that does not require open surgery and is especially successful for very small and low-risk GIST. A retrospective examination of 32 patients treated with ER between 2012 and 2023 was conducted to analyse clinical and pathological characteristics, effectiveness of therapy, and long-term prognosis. The findings demonstrate en bloc resection was achieved in 96.9% of cases with an R0 resection rate of 75% with a median size of tumour was approximately 2.12 cm. Post-surgery complication like hydrothorax, post-endoscopic submucosal dissection electrocoagulation syndrome occurred in about 25% of cases which later go resolved by conservative treatment. Recurrence of GIST was approximately 9.4% primarily in high-risk cases. ER should be widely adopted in clinical practise preferably for managing low-risk oesophageal GIST because of its high success rate, low recurrence rates and excellent survival results, ensuring better patient prognosis.

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来源期刊
World Journal of Gastrointestinal Endoscopy
World Journal of Gastrointestinal Endoscopy GASTROENTEROLOGY & HEPATOLOGY-
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