经皮穴位电刺激(TEAS)促进肺癌日间手术术后恢复:一项随机对照试验。

IF 2.5 3区 医学 Q2 CLINICAL NEUROLOGY
Journal of Pain Research Pub Date : 2025-06-17 eCollection Date: 2025-01-01 DOI:10.2147/JPR.S529193
Siyin Wu, Jieqiong Lou, Houdong Zou, Wei Wang, Yunyun Zhang, Yunhua Xu, Xumin Hou, Jingxiang Wu
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引用次数: 0

摘要

背景:日间胸外科手术需要有效的镇痛和快速的恢复。本研究评估经皮穴位电刺激(TEAS)是否能减少肺癌手术后疼痛和镇痛药的使用。方法:在上海某三级医院进行的一项随机、假对照试验中,纳入了100例(18-70岁,ASA I-II)接受日间肺癌手术(视频胸腔镜肺楔形切除术)的患者。参与者在麻醉后护理病房随机接受tea或假tea。tea组在合谷(LI4)和内关(PC6)处进行30分钟的刺激,而sham组在不刺激的情况下进行电极放置。主要终点是术后24小时疼痛强度,采用视觉模拟评分(VAS)测量。次要结局是术后1小时和12小时的VAS评分、镇痛药消耗、中至重度疼痛发生率(VAS评分bbbb4)、术后恶心呕吐发生率(PONV)、恢复质量(QoR-15)评分和安全事件。结果:tea组VAS评分在1小时(0.94 vs 1.84, p = 0.006)、12小时(2.00 vs 5.40, p < 0.001)和24小时(1.72 vs 4.02, p < 0.001)显著降低。12小时内中重度疼痛发生率降低(12.0% vs 74.0%, p < 0.001)。tea组的镇痛药用量较低。TEAS组24 h QoR-15评分较高(130.8比115.9,p < 0.001)。在PONV、住院时间或不良事件方面没有观察到显著差异。结论:TEAS减少了肺癌术后疼痛和镇痛药的使用,提高了肺癌手术的恢复质量,并支持其与ERAS方案的整合。试验注册:ChiCTR2200066600。https://www.chictr.org.cn/showproj.html?proj=187035。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Transcutaneous Electrical Acupoint Stimulation (TEAS) Facilitates Postoperative Recovery in Day Lung Cancer Surgery: A Randomized Controlled Trial.

Background: Day thoracic surgery requires effective analgesia and a rapid recovery. This study evaluated whether Transcutaneous Electrical Acupoint Stimulation (TEAS) reduces postoperative pain and analgesic use in lung cancer surgery.

Methods: In this randomized, sham-controlled trial at a tertiary hospital in Shanghai, 100 patients (18-70 years old, ASA I-II) who underwent day lung cancer surgery (video-assisted thoracoscopic pulmonary wedge resection) were enrolled. Participants were randomized to receive either TEAS or sham TEAS in the Post-Anesthesia Care Unit. The TEAS group received 30 minutes of stimulation at Hegu (LI4) and Neiguan (PC6), whereas the sham group received electrode placement without stimulation. Primary outcome was pain intensity 24 h after surgery, measured using the visual analog scale (VAS). Secondary outcomes were VAS scores at 1 h and 12 h post-surgery, analgesic consumption, incidence of moderate-to-severe pain (VAS score >4), incidence of postoperative nausea and vomiting (PONV), Quality of Recovery (QoR-15) scores, and safety events.

Results: The TEAS group had significantly lower VAS scores at 1 hour (0.94 vs 1.84, p = 0.006), 12 hours (2.00 vs 5.40, p < 0.001), and 24 hours (1.72 vs 4.02, p < 0.001). The incidence of moderate-to-severe pain within 12 hours was reduced (12.0% vs 74.0%, p < 0.001). Analgesic consumption was lower in the TEAS group. The QoR-15 scores at 24 h were higher in the TEAS group (130.8 vs 115.9, p < 0.001). No significant differences were observed in PONV, length of hospital stay, or adverse events.

Conclusion: TEAS reduces postoperative pain and analgesic use, improves the recovery quality in lung cancer surgery, and supports its integration into ERAS protocols.

Trial registration: ChiCTR2200066600. https://www.chictr.org.cn/showproj.html?proj=187035.

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来源期刊
Journal of Pain Research
Journal of Pain Research CLINICAL NEUROLOGY-
CiteScore
4.50
自引率
3.70%
发文量
411
审稿时长
16 weeks
期刊介绍: Journal of Pain Research is an international, peer-reviewed, open access journal that welcomes laboratory and clinical findings in the fields of pain research and the prevention and management of pain. Original research, reviews, symposium reports, hypothesis formation and commentaries are all considered for publication. Additionally, the journal now welcomes the submission of pain-policy-related editorials and commentaries, particularly in regard to ethical, regulatory, forensic, and other legal issues in pain medicine, and to the education of pain practitioners and researchers.
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