Raghad Mahmoud Alsuliman, Heba Haj Saleh, Huda Hossin, Ibrahim Labbad
{"title":"布鲁氏菌病所致隐匿性脑膜炎1例报告。","authors":"Raghad Mahmoud Alsuliman, Heba Haj Saleh, Huda Hossin, Ibrahim Labbad","doi":"10.1186/s13256-025-05352-6","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Brucellosis is a rare etiology for chronic neurological infections, posing a diagnostic challenge for patients due to the potential for atypical symptoms.</p><p><strong>Case presentation: </strong>We are presenting a rare case report of Brucella meningitis. A 25-year-old unmarried Syrian female without any prior medical history presented with a progressive headache that had persisted for over 10 months, accompanied by nausea and vomiting that worsened when lying down. Initially, the diagnosis was attributed to idiopathic intracrainal hypertension due to the absence of systemic symptoms and an incorrect cerebrospinal fluid test. A comprehensive re-evaluation was performed, and Wright test was positive and Brucella antibodies were detected in both blood and cerebrospinal fluid samples. This ultimately confirmed the diagnosis of Brucella meningitis.</p><p><strong>Conclusion: </strong>Our report emphasizes the importance of considering atypical bacteria as a cause for neuro-infection, and a wide investigation should be conducted to reach an accurate diagnosis and reevaluation of tests when necessary.</p>","PeriodicalId":16236,"journal":{"name":"Journal of Medical Case Reports","volume":"19 1","pages":"292"},"PeriodicalIF":0.9000,"publicationDate":"2025-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12186383/pdf/","citationCount":"0","resultStr":"{\"title\":\"Insidious meningitis induced by brucellosis: a case report.\",\"authors\":\"Raghad Mahmoud Alsuliman, Heba Haj Saleh, Huda Hossin, Ibrahim Labbad\",\"doi\":\"10.1186/s13256-025-05352-6\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Brucellosis is a rare etiology for chronic neurological infections, posing a diagnostic challenge for patients due to the potential for atypical symptoms.</p><p><strong>Case presentation: </strong>We are presenting a rare case report of Brucella meningitis. A 25-year-old unmarried Syrian female without any prior medical history presented with a progressive headache that had persisted for over 10 months, accompanied by nausea and vomiting that worsened when lying down. Initially, the diagnosis was attributed to idiopathic intracrainal hypertension due to the absence of systemic symptoms and an incorrect cerebrospinal fluid test. A comprehensive re-evaluation was performed, and Wright test was positive and Brucella antibodies were detected in both blood and cerebrospinal fluid samples. This ultimately confirmed the diagnosis of Brucella meningitis.</p><p><strong>Conclusion: </strong>Our report emphasizes the importance of considering atypical bacteria as a cause for neuro-infection, and a wide investigation should be conducted to reach an accurate diagnosis and reevaluation of tests when necessary.</p>\",\"PeriodicalId\":16236,\"journal\":{\"name\":\"Journal of Medical Case Reports\",\"volume\":\"19 1\",\"pages\":\"292\"},\"PeriodicalIF\":0.9000,\"publicationDate\":\"2025-06-23\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12186383/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Medical Case Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1186/s13256-025-05352-6\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Medical Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1186/s13256-025-05352-6","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
Insidious meningitis induced by brucellosis: a case report.
Background: Brucellosis is a rare etiology for chronic neurological infections, posing a diagnostic challenge for patients due to the potential for atypical symptoms.
Case presentation: We are presenting a rare case report of Brucella meningitis. A 25-year-old unmarried Syrian female without any prior medical history presented with a progressive headache that had persisted for over 10 months, accompanied by nausea and vomiting that worsened when lying down. Initially, the diagnosis was attributed to idiopathic intracrainal hypertension due to the absence of systemic symptoms and an incorrect cerebrospinal fluid test. A comprehensive re-evaluation was performed, and Wright test was positive and Brucella antibodies were detected in both blood and cerebrospinal fluid samples. This ultimately confirmed the diagnosis of Brucella meningitis.
Conclusion: Our report emphasizes the importance of considering atypical bacteria as a cause for neuro-infection, and a wide investigation should be conducted to reach an accurate diagnosis and reevaluation of tests when necessary.
期刊介绍:
JMCR is an open access, peer-reviewed online journal that will consider any original case report that expands the field of general medical knowledge. Reports should show one of the following: 1. Unreported or unusual side effects or adverse interactions involving medications 2. Unexpected or unusual presentations of a disease 3. New associations or variations in disease processes 4. Presentations, diagnoses and/or management of new and emerging diseases 5. An unexpected association between diseases or symptoms 6. An unexpected event in the course of observing or treating a patient 7. Findings that shed new light on the possible pathogenesis of a disease or an adverse effect