eus引导下乙醇消融治疗实性假乳头状肿瘤的4例研究

IF 0.9 Q4 GASTROENTEROLOGY & HEPATOLOGY

Clinical Journal of Gastroenterology Pub Date : 2025-08-01 Epub Date: 2025-06-24 DOI:10.1007/s12328-025-02163-6

Yousik Myung, Kazuo Hara, Shin Haba, Takamichi Kuwahara, Nozomi Okuno, Hiroki Koda, Indria Melianti, Adwoa Agyei-Nkansah

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引用次数: 0

摘要

背景/目的：胰腺的实性假乳头状肿瘤（SPN）是一种低恶性潜能的罕见肿瘤，尽管10-15%可能表现为侵袭性或转移性。本研究旨在评估内镜下超声引导下乙醇消融（EUS-EI）对非手术候选SPN患者的安全性和有效性。方法：4例拒绝或不符合手术条件的SPN患者在爱知县癌症中心接受EUS-EI治疗。评估了技术和临床结果以及不良事件。结果：所有患者均获得技术成功（100%）。3例（75%）患者临床成功，其中2例完全消融，1例肿瘤显著缩小。随访期间未发生重大不良事件及肿瘤复发。结论：EUS-EI可能是治疗非手术患者SPN的安全有效的选择。

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EUS-guided ethanol ablation in patients with solid pseudopapillary neoplasm: a four-case series.

Background/aims: Solid pseudopapillary neoplasm (SPN) of the pancreas is a rare tumor with low malignant potential, though 10-15% may show invasive or metastatic behavior. This study aimed to evaluate the safety and efficacy of endoscopic ultrasound-guided ethanol ablation (EUS-EI) in patients with SPN who were not surgical candidates.

Methods: Four patients with SPN who declined or were ineligible for surgery underwent EUS-EI at Aichi Cancer Center. Technical and clinical outcomes, as well as adverse events, were assessed.

Results: Technical success was achieved in all patients (100%). Clinical success was observed in three patients (75%), including two with complete ablation and one with significant tumor reduction. No major adverse events or tumor recurrence occurred during follow-up.

Conclusions: EUS-EI may be a safe and effective alternative for managing SPN in non-surgical candidates.

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来源期刊

Clinical Journal of Gastroenterology GASTROENTEROLOGY & HEPATOLOGY-

CiteScore

2.00

自引率

0.00%

发文量

182

期刊介绍： The journal publishes Case Reports and Clinical Reviews on all aspects of the digestive tract, liver, biliary tract, and pancreas. Critical Case Reports that show originality or have educational implications for diagnosis and treatment are especially encouraged for submission. Personal reviews of clinical gastroenterology are also welcomed. The journal aims for quick publication of such critical Case Reports and Clinical Reviews.