恶性肿瘤假面具：包涵阴性的单纯疱疹病毒直肠假瘤在HIV患者。

IF 0.5 Q4 GASTROENTEROLOGY & HEPATOLOGY

ACG Case Reports Journal Pub Date : 2025-06-20 eCollection Date: 2025-06-01 DOI:10.14309/crj.0000000000001745

Aaron C Nguyen, Moez Karim Aziz, Frederick B Peng, Nathan Spezia-Lindner, Georgia Huffman, Stefanos Millas, Roberto Cavazos

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引用次数: 0

摘要

单纯疱疹病毒（HSV）感染是人类最常见的性传播感染之一。然而，不典型的表现可能出现在免疫功能低下的患者，如结节、尖锐湿疣肿块或肥厚性病变。此外，在以往的文献中，对组织学染色阴性的HSV假肿瘤的讨论也不完全。我们报告了一位51岁的HIV-1控制良好的患者，他出现了直肠肿块，最初担心潜在的细菌感染或恶性肿瘤。尽管活检显示HSV免疫组化染色为阴性，但经静脉注射阿昔洛韦治疗后，肿块有所改善，最终提示直肠HSV假瘤。

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Malignancy Masquerade: Inclusion-Negative Herpes Simplex Virus Rectal Pseudotumor in a Patient With HIV.

Herpes simplex virus (HSV) infections are among the most common sexually transmitted infections in humans. However, atypical presentations may occur in immunocompromised patients such as nodules, condylomatous masses, or hypertrophic lesions. Even further, HSV pseudotumors with negative histologic staining have been incompletely discussed in previous literature. We present a 51-year-old patient with a history of well-controlled HIV-1, who presented with a rectal mass, originally concerning for underlying bacterial infection or malignancy. Despite negative HSV immunohistochemical staining on biopsy, the mass improved with empiric intravenous acyclovir therapy, ultimately suggestive of a rectal HSV pseudotumor.

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来源期刊

ACG Case Reports Journal GASTROENTEROLOGY & HEPATOLOGY-

自引率

14.30%

发文量

170

审稿时长

12 weeks

期刊介绍： ACG Case Reports Journal is a peer-reviewed, open-access publication that provides GI and hepatology fellows, private practice clinicians, and other healthcare providers an opportunity to share interesting case reports with their peers and with leaders in the field. ACG Case Reports Journal publishes case reports, images, videos and letters to the editor in all topics of gastroenterology and hepatology, including: Biliary Colon Endoscopy Esophagus Functional Bowel Disorders Inflammatory Bowel Disease Liver Nutrition and Obesity Pancreas Pathology Pediatric Small Bowel Stomach.