吸入芳香疗法对PCI血管造影患者的影响：系统回顾和荟萃分析

IF 1.7 Q2 Medicine

Advances in integrative medicine Pub Date : 2025-02-25 DOI:10.1016/j.aimed.2025.02.001

Mohamed Elsaid , Majd H. Alkhawaldeh , Mariam Abdelrauf Mahmoud , Ahmed Moumen , Moustafa Salem , Mohamed Fouad Abdrabo , Saad Abuzahra , Mohammed Ahmed Sadeq , Mohamed Hady Ashry , Abdelrahman Yousry Afify

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引用次数: 0

摘要

PCI/血管造影患者血流动力学不稳定和心理焦虑并不罕见。芳香疗法作为一种辅助干预的潜力，以减轻这些感觉和减少围手术期并发症已成为几项研究的主题。目的评价芳香疗法在PCI/血管造影患者中的疗效。方法对截至2023年2月的7个电子数据库（PubMed、Cochrane Library、Scopus、clinicaltrials、CINAHL、Embase和WHO ICTRP）进行全面检索，寻找相关研究。包括研究芳香疗法如何影响PCI/血管造影患者的随机对照试验。焦虑、血压、心率、呼吸、疼痛和睡眠质量都是收集和分析的结果测量值。当异质性显著时，我们使用R studio （V4.1.3）中的“meta”包进行meta分析，采用随机效应模型(I2 >；50 %或p <； 0.05)此外，使用修订后的Cochrane偏倚风险工具（RoB2）评估偏倚风险。结果纳入5项随机对照试验，共纳入449例患者。芳香疗法在减少焦虑方面具有统计学意义(SMD = - 0.56；95 % ci [-0.98；−0.14],p & lt; 0.01,(I2 = 66 % p = 0.05])、心率(SMD =−0.42,95 % CI(−0.68;- 0.17], p <； 0.01)，收缩压和舒张压(SMD = - 0.29；95 % CI (-0.49;−0.10],p & lt; 0.01,(I2 = 33 % p = 0.20]),(SMD =−0.22;95 % ci [-0.41；−0.03],p = 0.03,[I2 = 0 %,p = 0.54])。分别。此外，据报道，在两项不同的研究中，与对照组相比，吸入芳香疗法与疼痛评分显著降低有关（p <； 0.05）。两组患者的总呼吸率差异无统计学意义（p >； 0.05）。在偏倚风险方面，有3项研究显示低风险，只有1项研究显示高偏倚风险。结论芳香疗法可显著改善PCI/血管造影患者的焦虑、心率、收缩压和舒张压。然而，由于这些研究中没有盲性，这些结果应该谨慎解释，而且，芳香疗法方法的异质性已经被报道。因此，建议进一步的随机对照试验来比较这些方法，确定最佳剂量，治疗持续时间，并评估芳香疗法的长期效果和安全性。

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Effect of inhalation aromatherapy on patients undergoing PCI angiography: A systematic review and meta-analysis

Introduction

It is not uncommon for patients having PCI/angiography to encounter hemodynamic instability and psychological anxiety. The potential of aromatherapy as a supplementary intervention to mitigate these sensations and decrease perioperative complications has been the subject of several research.

Objectives

The study aims to evaluate the efficacy of aromatherapy in patients who underwent PCI/angiography.

Methods

A thorough search was carried out up to February 2023 across seven electronic databases (PubMed, Cochrane Library, Scopus, clinicaltrials, CINAHL, Embase, and WHO ICTRP) in order to find pertinent research. Included were RCTs looking into how aromatherapy affected PCI/angiography patients. Anxiety, blood pressure, heart rate, respiration, pain, and sleep quality were among the outcome measurements that were collected and analyzed. We performed the meta-analysis using “meta” package in R studio (V4.1.3) employing the random effects model when heterogeneity is significant (I² > 50 % or p < 0.05) Additionally, the risk of bias was assessed using the revised Cochrane risk of bias tool (RoB2).

Results

Five RCTs enrolling 449 patients were included. Aromatherapy demonstrated a statistically significant reduction in anxiety (SMD = −0.56; 95 % CI [-0.98; −0.14], p < 0.01, [I² = 66 %, p = 0.05]), heart rate (SMD= −0.42, 95 % CI [ −0.68; −0.17], p < 0.01), Systolic and diastolic blood Pressure (SMD = −0.29; 95 %CI [-0.49; −0.10], p < 0.01, [I² = 33 %, p = 0.20]), (SMD = −0.22; 95 % CI [-0.41; −0.03], p = 0.03, [I² = 0 %, p = 0.54]). respectively. Furthermore, inhalation aromatherapy was reportedly associated with a significant decrease in pain score compared to control in two different studies (p < 0.05). However, there was no statistically significant change in pooled respiratory rate (p > 0.05). Regarding the risk of bias, three studies showed low risk while only one showed high risk of bias.

Conclusion

Aromatherapy significantly improved anxiety, heart rate, SBP and DBP in patients underwent PCI/angiography. However, these results should be interpreted cautiously due to absence of blindness in such studies, moreover, heterogeneity of aromatherapy methods has been reported. Therefore, further RCTs are recommended to compare those methods, determine the optimal dosage, duration of treatment and to evaluate the long-term effects and safety profile of aromatherapy.

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来源期刊

Advances in integrative medicine INTEGRATIVE & COMPLEMENTARY MEDICINE-

CiteScore

3.20

自引率

11.80%

发文量

审稿时长

15 weeks

期刊介绍： Advances in Integrative Medicine (AIMED) is an international peer-reviewed, evidence-based research and review journal that is multi-disciplinary within the fields of Integrative and Complementary Medicine. The journal focuses on rigorous quantitative and qualitative research including systematic reviews, clinical trials and surveys, whilst also welcoming medical hypotheses and clinically-relevant articles and case studies disclosing practical learning tools for the consulting practitioner. By promoting research and practice excellence in the field, and cross collaboration between relevant practitioner groups and associations, the journal aims to advance the practice of IM, identify areas for future research, and improve patient health outcomes. International networking is encouraged through clinical innovation, the establishment of best practice and by providing opportunities for cooperation between organisations and communities.