{"title":"血浆置换术治疗恶性胆道梗阻术后持续性梗阻性黄疸疗效观察3例。","authors":"Yuhei Iwasa, Keisuke Iwata, Ryuichi Tezuka, Takuji Iwashita, Shinya Uemura, Shota Iwata, Yosuke Ohashi, Yuki Murayama, Masahito Shimizu","doi":"10.1007/s12328-025-02168-1","DOIUrl":null,"url":null,"abstract":"<p><p>We describe three cases in which plasmapheresis was effective for persistent obstructive jaundice, even after biliary drainage. All three cases involved resectable or borderline resectable malignant tumors that caused obstructive jaundice. Jaundice is refractory to biliary drainage and medication and results in prolonged hyperbilirubinemia. Plasmapheresis led to improvements in all cases. Plasmapheresis may be a treatment option for persistent obstructive jaundice resistant to standard therapies.</p>","PeriodicalId":10364,"journal":{"name":"Clinical Journal of Gastroenterology","volume":" ","pages":""},"PeriodicalIF":0.9000,"publicationDate":"2025-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Three cases in which plasmapheresis was effective for persistent obstructive jaundice due to malignant biliary obstruction after biliary drainage.\",\"authors\":\"Yuhei Iwasa, Keisuke Iwata, Ryuichi Tezuka, Takuji Iwashita, Shinya Uemura, Shota Iwata, Yosuke Ohashi, Yuki Murayama, Masahito Shimizu\",\"doi\":\"10.1007/s12328-025-02168-1\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>We describe three cases in which plasmapheresis was effective for persistent obstructive jaundice, even after biliary drainage. All three cases involved resectable or borderline resectable malignant tumors that caused obstructive jaundice. Jaundice is refractory to biliary drainage and medication and results in prolonged hyperbilirubinemia. Plasmapheresis led to improvements in all cases. Plasmapheresis may be a treatment option for persistent obstructive jaundice resistant to standard therapies.</p>\",\"PeriodicalId\":10364,\"journal\":{\"name\":\"Clinical Journal of Gastroenterology\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.9000,\"publicationDate\":\"2025-06-22\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical Journal of Gastroenterology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1007/s12328-025-02168-1\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"GASTROENTEROLOGY & HEPATOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Journal of Gastroenterology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/s12328-025-02168-1","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"GASTROENTEROLOGY & HEPATOLOGY","Score":null,"Total":0}
Three cases in which plasmapheresis was effective for persistent obstructive jaundice due to malignant biliary obstruction after biliary drainage.
We describe three cases in which plasmapheresis was effective for persistent obstructive jaundice, even after biliary drainage. All three cases involved resectable or borderline resectable malignant tumors that caused obstructive jaundice. Jaundice is refractory to biliary drainage and medication and results in prolonged hyperbilirubinemia. Plasmapheresis led to improvements in all cases. Plasmapheresis may be a treatment option for persistent obstructive jaundice resistant to standard therapies.
期刊介绍:
The journal publishes Case Reports and Clinical Reviews on all aspects of the digestive tract, liver, biliary tract, and pancreas. Critical Case Reports that show originality or have educational implications for diagnosis and treatment are especially encouraged for submission. Personal reviews of clinical gastroenterology are also welcomed. The journal aims for quick publication of such critical Case Reports and Clinical Reviews.