基于水凝胶的生物传感器技术在神经退行性疾病诊断中的最新进展。

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS
Seda Ayçiçek, Şule Coşkun Cevher, Selim Acar
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引用次数: 0

摘要

神经退行性疾病的早期诊断对于制定适当的治疗策略至关重要。目前的诊断方法有许多局限性和挑战。在神经退行性疾病诊断生物传感器的设计过程中,水凝胶等替代生物材料是备受关注的潜在候选材料。被称为水凝胶的交联亲水性聚合物的三维网络具有与生物组织相媲美的特性。将水凝胶整合到生物传感器设计中,用于诊断神经退行性疾病,具有功能和结构上的优势。本文综述了近年来基于水凝胶的生物传感器在神经退行性疾病检测方面的发展趋势、它们的设计、应用以及它们的优缺点。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Recent Trends in Hydrogel-Based Biosensor Technology for the Diagnosis of Neurodegenerative Diseases.

Early diagnosis of neurodegenerative diseases is essential for the development of appropriate treatment strategies. Current diagnostic methods have a number of limitations and challenges. Alternative biomaterials such as hydrogels are potential candidates that are attracting attention in the design process of biosensors for the diagnosis of neurodegenerative diseases. Three-dimensional networks of cross-linked hydrophilic polymers, known as hydrogels, have characteristics that are comparable to those of biological tissues. The integration of hydrogels into biosensor designs for the diagnosis of neurodegenerative diseases offers functionality and structural advantages. This review summarizes recent trends in hydrogel-based biosensors for the detection of neurodegenerative diseases, their design, applications, as well as a comprehensive overview of their advantages and disadvantages.

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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
期刊介绍: ACS Applied Bio Materials is an interdisciplinary journal publishing original research covering all aspects of biomaterials and biointerfaces including and beyond the traditional biosensing, biomedical and therapeutic applications. The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrates knowledge in the areas of materials, engineering, physics, bioscience, and chemistry into important bio applications. The journal is specifically interested in work that addresses the relationship between structure and function and assesses the stability and degradation of materials under relevant environmental and biological conditions.
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