Thu Thu Win Myint, Nick McIvor, Richard Douglas, Alana Cavadino, Mark Elwood
{"title":"2006-2020年间新西兰奥特罗阿地区口腔鳞状细胞癌的发病率、趋势和生存率","authors":"Thu Thu Win Myint, Nick McIvor, Richard Douglas, Alana Cavadino, Mark Elwood","doi":"10.31557/APJCP.2025.26.6.2015","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Over recent decades, there have been changes in the incidence of squamous cell carcinoma of the oral cavity (OCSCC) in many countries. However, recent data on OCSCC in New Zealand has not been examined. This study examines the current incidence, trends and survival of OCSCC in New Zealand and identifies demographic differences by age, sex and ethnicity.</p><p><strong>Method: </strong>Patients with a primary diagnosis of OCSCC between 2006 and 2020 were retrieved from the National Cancer Registry. Age-standardised incidence rates (ASRs) were calculated and compared using age-standardised incidence rate ratios (ASRRs). Time trends were assessed by joinpoint regression with annual percentage changes, and overall and relative survival rates were estimated.</p><p><strong>Results: </strong>Over 15 years, 2094 cases of OCSCC were identified, and the average annual incidence was 2.1 per 100,000. The rates were higher in males (ASRR= 1.4 compared to females), older age groups (ASRR=11.3 in 50-69 years; ASRR=25.4 in 70+ years compared to <50 years), and Pasifika (ASRR=1.4, compared to European). OCSCC incidence increased significantly between 2009 and 2017 and decreased between 2017 and 2020. Females followed the same pattern of trends as overall OCSCC, while trends in males showed no significant changes. The survival outcome of OCSCC at five years was 57% and 66% for absolute and relative survival, respectively. Survival outcomes were poorer in males (HR = 1.20 compared to females), older age groups (HR=1.77 in 50-69 years; HR=4.21 in 70+ years compared to <50 years), Māori (HR=1.37 compared to European) and tumours originated from the floor of mouth (HR=1.40), palate (HR=1.47) and buccal (HR=1.54) compared to tongue.</p><p><strong>Conclusion: </strong>This study shows that the incidence of OCSCC overall and in females increased from 2009 to 2017, but declined significantly after 2017 in New Zealand. Incidence and survival rates are influenced by sex, age, ethnicity and subsite.</p>","PeriodicalId":55451,"journal":{"name":"Asian Pacific Journal of Cancer Prevention","volume":"26 6","pages":"2015-2023"},"PeriodicalIF":0.0000,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Incidence, Trends and Survival of Oral Cavity Squamous Cell Carcinoma in Aotearoa New Zealand over 15 Years (2006-2020).\",\"authors\":\"Thu Thu Win Myint, Nick McIvor, Richard Douglas, Alana Cavadino, Mark Elwood\",\"doi\":\"10.31557/APJCP.2025.26.6.2015\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Over recent decades, there have been changes in the incidence of squamous cell carcinoma of the oral cavity (OCSCC) in many countries. However, recent data on OCSCC in New Zealand has not been examined. This study examines the current incidence, trends and survival of OCSCC in New Zealand and identifies demographic differences by age, sex and ethnicity.</p><p><strong>Method: </strong>Patients with a primary diagnosis of OCSCC between 2006 and 2020 were retrieved from the National Cancer Registry. Age-standardised incidence rates (ASRs) were calculated and compared using age-standardised incidence rate ratios (ASRRs). Time trends were assessed by joinpoint regression with annual percentage changes, and overall and relative survival rates were estimated.</p><p><strong>Results: </strong>Over 15 years, 2094 cases of OCSCC were identified, and the average annual incidence was 2.1 per 100,000. The rates were higher in males (ASRR= 1.4 compared to females), older age groups (ASRR=11.3 in 50-69 years; ASRR=25.4 in 70+ years compared to <50 years), and Pasifika (ASRR=1.4, compared to European). OCSCC incidence increased significantly between 2009 and 2017 and decreased between 2017 and 2020. Females followed the same pattern of trends as overall OCSCC, while trends in males showed no significant changes. The survival outcome of OCSCC at five years was 57% and 66% for absolute and relative survival, respectively. Survival outcomes were poorer in males (HR = 1.20 compared to females), older age groups (HR=1.77 in 50-69 years; HR=4.21 in 70+ years compared to <50 years), Māori (HR=1.37 compared to European) and tumours originated from the floor of mouth (HR=1.40), palate (HR=1.47) and buccal (HR=1.54) compared to tongue.</p><p><strong>Conclusion: </strong>This study shows that the incidence of OCSCC overall and in females increased from 2009 to 2017, but declined significantly after 2017 in New Zealand. Incidence and survival rates are influenced by sex, age, ethnicity and subsite.</p>\",\"PeriodicalId\":55451,\"journal\":{\"name\":\"Asian Pacific Journal of Cancer Prevention\",\"volume\":\"26 6\",\"pages\":\"2015-2023\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-06-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Asian Pacific Journal of Cancer Prevention\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.31557/APJCP.2025.26.6.2015\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Asian Pacific Journal of Cancer Prevention","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.31557/APJCP.2025.26.6.2015","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"Medicine","Score":null,"Total":0}
Incidence, Trends and Survival of Oral Cavity Squamous Cell Carcinoma in Aotearoa New Zealand over 15 Years (2006-2020).
Background: Over recent decades, there have been changes in the incidence of squamous cell carcinoma of the oral cavity (OCSCC) in many countries. However, recent data on OCSCC in New Zealand has not been examined. This study examines the current incidence, trends and survival of OCSCC in New Zealand and identifies demographic differences by age, sex and ethnicity.
Method: Patients with a primary diagnosis of OCSCC between 2006 and 2020 were retrieved from the National Cancer Registry. Age-standardised incidence rates (ASRs) were calculated and compared using age-standardised incidence rate ratios (ASRRs). Time trends were assessed by joinpoint regression with annual percentage changes, and overall and relative survival rates were estimated.
Results: Over 15 years, 2094 cases of OCSCC were identified, and the average annual incidence was 2.1 per 100,000. The rates were higher in males (ASRR= 1.4 compared to females), older age groups (ASRR=11.3 in 50-69 years; ASRR=25.4 in 70+ years compared to <50 years), and Pasifika (ASRR=1.4, compared to European). OCSCC incidence increased significantly between 2009 and 2017 and decreased between 2017 and 2020. Females followed the same pattern of trends as overall OCSCC, while trends in males showed no significant changes. The survival outcome of OCSCC at five years was 57% and 66% for absolute and relative survival, respectively. Survival outcomes were poorer in males (HR = 1.20 compared to females), older age groups (HR=1.77 in 50-69 years; HR=4.21 in 70+ years compared to <50 years), Māori (HR=1.37 compared to European) and tumours originated from the floor of mouth (HR=1.40), palate (HR=1.47) and buccal (HR=1.54) compared to tongue.
Conclusion: This study shows that the incidence of OCSCC overall and in females increased from 2009 to 2017, but declined significantly after 2017 in New Zealand. Incidence and survival rates are influenced by sex, age, ethnicity and subsite.
期刊介绍：
Cancer is a very complex disease. While many aspects of carcinoge-nesis and oncogenesis are known, cancer control and prevention at the community level is however still in its infancy. Much more work needs to be done and many more steps need to be taken before effective strategies are developed. The multidisciplinary approaches and efforts to understand and control cancer in an effective and efficient manner, require highly trained scientists in all branches of the cancer sciences, from cellular and molecular aspects to patient care and palliation.
The Asia Pacific Organization for Cancer Prevention (APOCP) and its official publication, the Asia Pacific Journal of Cancer Prevention (APJCP), have served the community of cancer scientists very well and intends to continue to serve in this capacity to the best of its abilities. One of the objectives of the APOCP is to provide all relevant and current scientific information on the whole spectrum of cancer sciences. They aim to do this by providing a forum for communication and propagation of original and innovative research findings that have relevance to understanding the etiology, progression, treatment, and survival of patients, through their journal. The APJCP with its distinguished, diverse, and Asia-wide team of editors, reviewers, and readers, ensure the highest standards of research communication within the cancer sciences community across Asia as well as globally.
The APJCP publishes original research results under the following categories:
-Epidemiology, detection and screening.
-Cellular research and bio-markers.
-Identification of bio-targets and agents with novel mechanisms of action.
-Optimal clinical use of existing anti-cancer agents, including combination therapies.
-Radiation and surgery.
-Palliative care.
-Patient adherence, quality of life, satisfaction.
-Health economic evaluations.
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