红碳点荧光探针在HCIO特异传感和成像中的应用。

IF 3.1 4区 化学 Q2 BIOCHEMICAL RESEARCH METHODS
Ying Peng, Haonan Yang, Mengyao Qu, Shaobing Zhang, Zheng Yang, Xiaodan Jia, Bo Wang, Xiangrong Liu
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引用次数: 0

摘要

HClO的选择性检测和跟踪是反映相关氧化应激过程和环境安全的关键。在这项研究中,我们提出了具有高荧光稳定性、强强度和高量子产率等优越光学性能的红发射碳点(CDs)。CDs对HClO表现出优异的选择性和灵敏度,具有优异的抗干扰性能和突出的检出限,表明基于CDs的荧光纳米探针不仅非常适合用溶液检测复杂水样中的HClO,而且可以作为有前景的荧光滤纸传感器进行快速检测。低细胞毒性和良好的生物相容性是活细胞中外源性和内源性HClO传感和成像的迫切需要,并鼓励CDs作为强大的成像工具,揭示HClO参与氧化应激过程的秘密,有助于相关疾病的早期诊断和治疗。临床试验编号不适用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Red Emissive Carbon Dots as Fluorescent Probe for Specific Sensing and Imaging of HCIO.

Selective detecting and tracking of HClO is crucial for reflecting related oxidative stress process and environmental safety. In this research, we present the red emissive carbon dots (CDs) with advantageous optical performances including high fluorescent stability, strong intensity and advanced quantum yield. The CDs showed excellent selectivity and sensitivity towards HClO with superior anti-interference performance and outstanding detection limit, indicating the CDs based fluorescent nanoprobe is not only highly suitable for detecting HClO in complicated water samples by solution, but also serve as prospective fluorescent filer paper sensor for fast detection. The low cytotoxicity and favorable biocompatibility are extremely demanded for sensing and imaging exogenous and endogenous HClO in living cells, and encourages the CDs as powerful imaging tool to unveil the mystery of HClO participant oxidative stress process, which would be beneficial for early diagnosis and therapeutics of related diseases. Clinical Trial Number Not applicable.

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来源期刊
Journal of Fluorescence
Journal of Fluorescence 化学-分析化学
CiteScore
4.60
自引率
7.40%
发文量
203
审稿时长
5.4 months
期刊介绍: Journal of Fluorescence is an international forum for the publication of peer-reviewed original articles that advance the practice of this established spectroscopic technique. Topics covered include advances in theory/and or data analysis, studies of the photophysics of aromatic molecules, solvent, and environmental effects, development of stationary or time-resolved measurements, advances in fluorescence microscopy, imaging, photobleaching/recovery measurements, and/or phosphorescence for studies of cell biology, chemical biology and the advanced uses of fluorescence in flow cytometry/analysis, immunology, high throughput screening/drug discovery, DNA sequencing/arrays, genomics and proteomics. Typical applications might include studies of macromolecular dynamics and conformation, intracellular chemistry, and gene expression. The journal also publishes papers that describe the synthesis and characterization of new fluorophores, particularly those displaying unique sensitivities and/or optical properties. In addition to original articles, the Journal also publishes reviews, rapid communications, short communications, letters to the editor, topical news articles, and technical and design notes.
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