Ying Peng, Haonan Yang, Mengyao Qu, Shaobing Zhang, Zheng Yang, Xiaodan Jia, Bo Wang, Xiangrong Liu
{"title":"红碳点荧光探针在HCIO特异传感和成像中的应用。","authors":"Ying Peng, Haonan Yang, Mengyao Qu, Shaobing Zhang, Zheng Yang, Xiaodan Jia, Bo Wang, Xiangrong Liu","doi":"10.1007/s10895-025-04411-x","DOIUrl":null,"url":null,"abstract":"<p><p>Selective detecting and tracking of HClO is crucial for reflecting related oxidative stress process and environmental safety. In this research, we present the red emissive carbon dots (CDs) with advantageous optical performances including high fluorescent stability, strong intensity and advanced quantum yield. The CDs showed excellent selectivity and sensitivity towards HClO with superior anti-interference performance and outstanding detection limit, indicating the CDs based fluorescent nanoprobe is not only highly suitable for detecting HClO in complicated water samples by solution, but also serve as prospective fluorescent filer paper sensor for fast detection. The low cytotoxicity and favorable biocompatibility are extremely demanded for sensing and imaging exogenous and endogenous HClO in living cells, and encourages the CDs as powerful imaging tool to unveil the mystery of HClO participant oxidative stress process, which would be beneficial for early diagnosis and therapeutics of related diseases. Clinical Trial Number Not applicable.</p>","PeriodicalId":15800,"journal":{"name":"Journal of Fluorescence","volume":" ","pages":""},"PeriodicalIF":3.1000,"publicationDate":"2025-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Red Emissive Carbon Dots as Fluorescent Probe for Specific Sensing and Imaging of HCIO.\",\"authors\":\"Ying Peng, Haonan Yang, Mengyao Qu, Shaobing Zhang, Zheng Yang, Xiaodan Jia, Bo Wang, Xiangrong Liu\",\"doi\":\"10.1007/s10895-025-04411-x\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Selective detecting and tracking of HClO is crucial for reflecting related oxidative stress process and environmental safety. In this research, we present the red emissive carbon dots (CDs) with advantageous optical performances including high fluorescent stability, strong intensity and advanced quantum yield. The CDs showed excellent selectivity and sensitivity towards HClO with superior anti-interference performance and outstanding detection limit, indicating the CDs based fluorescent nanoprobe is not only highly suitable for detecting HClO in complicated water samples by solution, but also serve as prospective fluorescent filer paper sensor for fast detection. The low cytotoxicity and favorable biocompatibility are extremely demanded for sensing and imaging exogenous and endogenous HClO in living cells, and encourages the CDs as powerful imaging tool to unveil the mystery of HClO participant oxidative stress process, which would be beneficial for early diagnosis and therapeutics of related diseases. Clinical Trial Number Not applicable.</p>\",\"PeriodicalId\":15800,\"journal\":{\"name\":\"Journal of Fluorescence\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":3.1000,\"publicationDate\":\"2025-06-21\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Fluorescence\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://doi.org/10.1007/s10895-025-04411-x\",\"RegionNum\":4,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"BIOCHEMICAL RESEARCH METHODS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Fluorescence","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1007/s10895-025-04411-x","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"BIOCHEMICAL RESEARCH METHODS","Score":null,"Total":0}
Red Emissive Carbon Dots as Fluorescent Probe for Specific Sensing and Imaging of HCIO.
Selective detecting and tracking of HClO is crucial for reflecting related oxidative stress process and environmental safety. In this research, we present the red emissive carbon dots (CDs) with advantageous optical performances including high fluorescent stability, strong intensity and advanced quantum yield. The CDs showed excellent selectivity and sensitivity towards HClO with superior anti-interference performance and outstanding detection limit, indicating the CDs based fluorescent nanoprobe is not only highly suitable for detecting HClO in complicated water samples by solution, but also serve as prospective fluorescent filer paper sensor for fast detection. The low cytotoxicity and favorable biocompatibility are extremely demanded for sensing and imaging exogenous and endogenous HClO in living cells, and encourages the CDs as powerful imaging tool to unveil the mystery of HClO participant oxidative stress process, which would be beneficial for early diagnosis and therapeutics of related diseases. Clinical Trial Number Not applicable.
期刊介绍:
Journal of Fluorescence is an international forum for the publication of peer-reviewed original articles that advance the practice of this established spectroscopic technique. Topics covered include advances in theory/and or data analysis, studies of the photophysics of aromatic molecules, solvent, and environmental effects, development of stationary or time-resolved measurements, advances in fluorescence microscopy, imaging, photobleaching/recovery measurements, and/or phosphorescence for studies of cell biology, chemical biology and the advanced uses of fluorescence in flow cytometry/analysis, immunology, high throughput screening/drug discovery, DNA sequencing/arrays, genomics and proteomics. Typical applications might include studies of macromolecular dynamics and conformation, intracellular chemistry, and gene expression. The journal also publishes papers that describe the synthesis and characterization of new fluorophores, particularly those displaying unique sensitivities and/or optical properties. In addition to original articles, the Journal also publishes reviews, rapid communications, short communications, letters to the editor, topical news articles, and technical and design notes.