{"title":"封底内：近红外有机室温磷光探针靶向成纤维细胞激活蛋白用于肝癌手术导航","authors":"Jinghua Li, Juqing Gu, Liangxuan Ding, Xiaomian Li, Peng Xia, Fusheng Liu, Xi Chen, Weijie Ma, Yong He, Qianqian Li, Zhen Li, Yufeng Yuan","doi":"10.1002/agt2.70083","DOIUrl":null,"url":null,"abstract":"<p>This study developed an actively targeted near-infrared organic room-temperature phosphorescent probe, TPE-4BT FAPI, designed to specifically target fibroblast activation protein (FAP) in the liver cancer microenvironment. The probe enables precise tumor localization and margin delineation under visible light irradiation, demonstrating significant clinical translational potential for guiding liver tumor resection and achieving accurate surgical excision of liver cancer (e70031).\n\n <figure>\n <div><picture>\n <source></source></picture><p></p>\n </div>\n </figure></p>","PeriodicalId":72127,"journal":{"name":"Aggregate (Hoboken, N.J.)","volume":"6 6","pages":""},"PeriodicalIF":13.9000,"publicationDate":"2025-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/agt2.70083","citationCount":"0","resultStr":"{\"title\":\"Inside Back Cover: Near-Infrared Organic Room Temperature Phosphorescent Probes Targeting Fibroblast Activation Protein for Surgical Navigation of Liver Cancer\",\"authors\":\"Jinghua Li, Juqing Gu, Liangxuan Ding, Xiaomian Li, Peng Xia, Fusheng Liu, Xi Chen, Weijie Ma, Yong He, Qianqian Li, Zhen Li, Yufeng Yuan\",\"doi\":\"10.1002/agt2.70083\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>This study developed an actively targeted near-infrared organic room-temperature phosphorescent probe, TPE-4BT FAPI, designed to specifically target fibroblast activation protein (FAP) in the liver cancer microenvironment. The probe enables precise tumor localization and margin delineation under visible light irradiation, demonstrating significant clinical translational potential for guiding liver tumor resection and achieving accurate surgical excision of liver cancer (e70031).\\n\\n <figure>\\n <div><picture>\\n <source></source></picture><p></p>\\n </div>\\n </figure></p>\",\"PeriodicalId\":72127,\"journal\":{\"name\":\"Aggregate (Hoboken, N.J.)\",\"volume\":\"6 6\",\"pages\":\"\"},\"PeriodicalIF\":13.9000,\"publicationDate\":\"2025-06-22\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1002/agt2.70083\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Aggregate (Hoboken, N.J.)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/agt2.70083\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Aggregate (Hoboken, N.J.)","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/agt2.70083","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
Inside Back Cover: Near-Infrared Organic Room Temperature Phosphorescent Probes Targeting Fibroblast Activation Protein for Surgical Navigation of Liver Cancer
This study developed an actively targeted near-infrared organic room-temperature phosphorescent probe, TPE-4BT FAPI, designed to specifically target fibroblast activation protein (FAP) in the liver cancer microenvironment. The probe enables precise tumor localization and margin delineation under visible light irradiation, demonstrating significant clinical translational potential for guiding liver tumor resection and achieving accurate surgical excision of liver cancer (e70031).
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