加州医疗保险受益人青光眼与昼夜节律睡眠障碍之间的关系

IF 4.2 1区医学 Q1 OPHTHALMOLOGY

American Journal of Ophthalmology Pub Date : 2025-06-20 DOI:10.1016/j.ajo.2025.06.021

Martin Ramirez , Ken Kitayama , Allan Puran , Victoria L. Tseng , Fei Yu , Anne L. Coleman

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引用次数: 0

摘要

研究加州医疗保险受益人青光眼、昼夜节律睡眠障碍（CRSD）和任何睡眠-觉醒障碍之间的关系。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

The Associations Between Glaucoma and Circadian Rhythm Sleep Disorders in California Medicare Beneficiaries

Purpose

To examine the associations between glaucoma, circadian rhythm sleep disorders (CRSD), and any sleep-wake disorders in California (CA) Medicare beneficiaries.

Design

Cross-sectional study.

Subjects

All 2019 CA Medicare beneficiaries who were ≥65 years old, had both Parts A & B coverage, and had ≥1 Part B claim.

Methods

The primary exposure was a diagnosis of glaucoma as defined by International Classification of Diseases, 10th revision codes. The primary outcome was CRSD, and the secondary outcome was any sleep-wake disorder, defined by International Classification of Diseases, 10th revision codes. The associations between glaucoma, CRSD, and any sleep-wake disorders were estimated using multivariable logistic regression models adjusting for age, sex, race and ethnicity, age-related macular degeneration, diabetic retinopathy, cataracts, pseudophakia, and systemic disease burden defined by Charlson Comorbidity Index score. The effect estimate was expressed as an adjusted odds ratio (aOR) with a 95% confidence interval (CI).

Main Outcome Measures

Odds ratios between exposures and outcomes.

Results

The study population included 2,717,346 CA Medicare beneficiaries meeting inclusion criteria. Of those, 220,662 (8.1%) had glaucoma, 3,202 (0.12%) had CRSD, and 355,390 (13.1%) had any sleep-wake disorder. In the adjusted logistic regression models, beneficiaries with glaucoma had greater adjusted odds of CRSD (aOR: 1.20; 95% CI: 1.06-1.35; P = .0031) and of any sleep-wake disorder (aOR: 1.12; 95% CI: 1.11-1.13; P < .001) compared to beneficiaries without glaucoma.

Conclusions

In the 2019 CA Medicare population, beneficiaries with glaucoma had increased likelihood of CRSD and of any sleep-wake disorder. Further investigations are needed to characterize mechanisms of these associations and to examine the impact of glaucoma treatment on sleep-wake disorders.

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来源期刊

American Journal of Ophthalmology 医学-眼科学

CiteScore

9.20

自引率

7.10%

发文量

406

审稿时长

36 days

期刊介绍： The American Journal of Ophthalmology is a peer-reviewed, scientific publication that welcomes the submission of original, previously unpublished manuscripts directed to ophthalmologists and visual science specialists describing clinical investigations, clinical observations, and clinically relevant laboratory investigations. Published monthly since 1884, the full text of the American Journal of Ophthalmology and supplementary material are also presented online at www.AJO.com and on ScienceDirect. The American Journal of Ophthalmology publishes Full-Length Articles, Perspectives, Editorials, Correspondences, Books Reports and Announcements. Brief Reports and Case Reports are no longer published. We recommend submitting Brief Reports and Case Reports to our companion publication, the American Journal of Ophthalmology Case Reports. Manuscripts are accepted with the understanding that they have not been and will not be published elsewhere substantially in any format, and that there are no ethical problems with the content or data collection. Authors may be requested to produce the data upon which the manuscript is based and to answer expeditiously any questions about the manuscript or its authors.