心脏死亡供者的马蹄肾移植一例报告。

IF 0.8 4区 医学 Q4 IMMUNOLOGY
Luca Perin , Maurizio Romano , Enrico Dalla Bona , Michele Finotti , Alessandro Iacomino , Margherita Mangino , Filomena Sergi , Rossana Maffei , Maurizio Nordio , Paolo Zanatta , Giacomo Zanus
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引用次数: 0

摘要

使用具有先天性形态异常的边缘肾供体,如“马蹄形”肾,是扩大供体池的一种解决方案。马蹄肾的血管和泌尿解剖结构是复杂的。这些患者更常发生肾积水、膀胱输尿管反流、尿路感染和尿石症。马蹄形肾可以“整体”移植,也可以“分裂”后作为单个肾脏移植。一名54岁终末期肾衰竭患者接受血液透析4年,移植了来自心脏死亡(DCD) III型马斯特里赫特供者的“马蹄形”移植物。术前计算机断层扫描(CT)显示存在“马蹄形”肾,由于两个肾脏之间存在共享的下极肾动脉而无法分割。除右肾盂轻微扩张外,收集系统未见异常。下腔静脉远端与髂外静脉端侧吻合。供体左髂总动脉端侧与髂外动脉缝合。双J (DJ)支架置入后,输尿管单独植入。无围手术期并发症。用ATG诱导免疫抑制治疗,随后引入他克莫司和霉酚酸酯。在4个月的随访中,患者出现了经皮引流的淋巴囊肿。3个月后取出DJ支架。马蹄形肾的供体,在没有泌尿系统病理史的情况下,即使在DCD环境下,也可以通过计划适当的术前策略来考虑移植。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Horseshoe Kidney Transplantation from a Deceased Cardiac Death Donor: A Case Report
The use of marginal kidney donors with congenital morphological anomalies, such as the “horseshoe” kidney, presents itself as a solution to expand the donor pool. The vascular and urinary anatomy of the horseshoe kidney is complex. These patients are more frequently affected by hydronephrosis, vesicoureteral reflux, urinary tract infections, and urolithiasis. The horseshoe kidney can be transplanted “en bloc” or as a single kidney after “splitting.” A 54-year-old patient with end-stage renal failure, on hemodialysis for 4 years, was transplanted with a “horseshoe” graft from a deceased cardiac death (DCD) III Maastricht-type donor. The “preoperative” computed tomography (CT) documented the presence of a “horseshoe” kidney, non-divisible due to the presence of a shared lower polar renal artery between both kidneys. There were no anomalies in the collecting systems except for a slight dilation of the right renal pelvis. The distal side of the inferior vena cava was anastomosed end-to-side with the external iliac vein. The left common iliac artery of the donor was sutured end-to-side with the external iliac artery. The ureters were implanted separately after the placement of the Double J (DJ) stents. There were no perioperative complications. Immunosuppressive therapy was induced with ATG and subsequently tacrolimus and mycophenolate mofetil were introduced. In 4 months of follow-up, the patient developed a lymphocele that was drained percutaneously. The DJ stents were removed after 3 months. The donor with a horseshoe kidney, in the absence of a urological pathological history, can be considered for transplantation even in a DCD setting by planning an appropriate preoperative strategy.
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来源期刊
Transplantation proceedings
Transplantation proceedings 医学-免疫学
CiteScore
1.70
自引率
0.00%
发文量
502
审稿时长
60 days
期刊介绍: Transplantation Proceedings publishes several different categories of manuscripts, all of which undergo extensive peer review by recognized authorities in the field prior to their acceptance for publication. The first type of manuscripts consists of sets of papers providing an in-depth expression of the current state of the art in various rapidly developing components of world transplantation biology and medicine. These manuscripts emanate from congresses of the affiliated transplantation societies, from Symposia sponsored by the Societies, as well as special Conferences and Workshops covering related topics. Transplantation Proceedings also publishes several special sections including publication of Clinical Transplantation Proceedings, being rapid original contributions of preclinical and clinical experiences. These manuscripts undergo review by members of the Editorial Board. Original basic or clinical science articles, clinical trials and case studies can be submitted to the journal?s open access companion title Transplantation Reports.
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