{"title":"鼻咽部神经鞘瘤异常表现的诊断和治疗:1例报告。","authors":"Srilatha Kavarthapu, Kaushik Saha, Vasudha Singh, Venkata Krishna Sundeep Nalamolu, Manish Singh","doi":"10.1186/s13256-025-05132-2","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Schwann cells are responsible for producing the myelin sheath that surrounds the axons in the peripheral nervous system. Benign tumors that originate from Schwann cells are called schwannomas or neurilemmomas. These tumors typically present as slow-growing, solitary, encapsulated masses, often associated with nerve trunks. Schwannomas are relatively rare, with 25-45% of cases occurring in the head and neck region.</p><p><strong>Case presentation: </strong>This report aims to describe the presentations, work-up, and treatment of a 38-year-old Indian female patient with head and neck schwannoma in an atypical location. It was an incidental swelling noted during functional endoscopic sinus surgery. The tumor was found to be originating from the junction of the posterior and lateral pharyngeal wall near the lower edge of the torus tubarius on the left side. Complete surgical excision of the tumor was done in this case with no reported recurrence at 6 months' follow-up. The final diagnosis was made on the basis of histopathology and immunohistochemistry findings.</p><p><strong>Conclusion: </strong>Histopathology should serve as the foundation for a definitive diagnosis. Tumor removal can be carried out using minimally invasive surgery through the endoscopic approach, resulting in fewer complications and a lowered risk of morbidity.</p>","PeriodicalId":16236,"journal":{"name":"Journal of Medical Case Reports","volume":"19 1","pages":"289"},"PeriodicalIF":0.9000,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12181876/pdf/","citationCount":"0","resultStr":"{\"title\":\"Diagnosis and management of an unusual presentation of schwannoma in nasopharynx: a case report.\",\"authors\":\"Srilatha Kavarthapu, Kaushik Saha, Vasudha Singh, Venkata Krishna Sundeep Nalamolu, Manish Singh\",\"doi\":\"10.1186/s13256-025-05132-2\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Schwann cells are responsible for producing the myelin sheath that surrounds the axons in the peripheral nervous system. Benign tumors that originate from Schwann cells are called schwannomas or neurilemmomas. These tumors typically present as slow-growing, solitary, encapsulated masses, often associated with nerve trunks. Schwannomas are relatively rare, with 25-45% of cases occurring in the head and neck region.</p><p><strong>Case presentation: </strong>This report aims to describe the presentations, work-up, and treatment of a 38-year-old Indian female patient with head and neck schwannoma in an atypical location. It was an incidental swelling noted during functional endoscopic sinus surgery. The tumor was found to be originating from the junction of the posterior and lateral pharyngeal wall near the lower edge of the torus tubarius on the left side. Complete surgical excision of the tumor was done in this case with no reported recurrence at 6 months' follow-up. The final diagnosis was made on the basis of histopathology and immunohistochemistry findings.</p><p><strong>Conclusion: </strong>Histopathology should serve as the foundation for a definitive diagnosis. Tumor removal can be carried out using minimally invasive surgery through the endoscopic approach, resulting in fewer complications and a lowered risk of morbidity.</p>\",\"PeriodicalId\":16236,\"journal\":{\"name\":\"Journal of Medical Case Reports\",\"volume\":\"19 1\",\"pages\":\"289\"},\"PeriodicalIF\":0.9000,\"publicationDate\":\"2025-06-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12181876/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Medical Case Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1186/s13256-025-05132-2\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Medical Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1186/s13256-025-05132-2","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
Diagnosis and management of an unusual presentation of schwannoma in nasopharynx: a case report.
Background: Schwann cells are responsible for producing the myelin sheath that surrounds the axons in the peripheral nervous system. Benign tumors that originate from Schwann cells are called schwannomas or neurilemmomas. These tumors typically present as slow-growing, solitary, encapsulated masses, often associated with nerve trunks. Schwannomas are relatively rare, with 25-45% of cases occurring in the head and neck region.
Case presentation: This report aims to describe the presentations, work-up, and treatment of a 38-year-old Indian female patient with head and neck schwannoma in an atypical location. It was an incidental swelling noted during functional endoscopic sinus surgery. The tumor was found to be originating from the junction of the posterior and lateral pharyngeal wall near the lower edge of the torus tubarius on the left side. Complete surgical excision of the tumor was done in this case with no reported recurrence at 6 months' follow-up. The final diagnosis was made on the basis of histopathology and immunohistochemistry findings.
Conclusion: Histopathology should serve as the foundation for a definitive diagnosis. Tumor removal can be carried out using minimally invasive surgery through the endoscopic approach, resulting in fewer complications and a lowered risk of morbidity.
期刊介绍:
JMCR is an open access, peer-reviewed online journal that will consider any original case report that expands the field of general medical knowledge. Reports should show one of the following: 1. Unreported or unusual side effects or adverse interactions involving medications 2. Unexpected or unusual presentations of a disease 3. New associations or variations in disease processes 4. Presentations, diagnoses and/or management of new and emerging diseases 5. An unexpected association between diseases or symptoms 6. An unexpected event in the course of observing or treating a patient 7. Findings that shed new light on the possible pathogenesis of a disease or an adverse effect