封闭精神病院抗精神病药物引起的脂质代谢异常的临床管理:挑战和综合策略。

IF 3.9 2区 医学 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY
Jiakuan Tu, Yu Qiu, Yueting Zhang, Yang Yang, Yi Huang
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引用次数: 0

摘要

在封闭的精神病学环境中,抗精神病药物引起的脂质代谢异常构成了重大的临床挑战。由于患者活动能力有限、治疗依从性波动和饮食单一,传统管理难以充分平衡药物副作用与患者健康需求。本研究提出了一个涉及监测、干预和跨学科合作的综合框架。它包括一个全面的“入院干预”监测系统,低血糖饮食结合部分控制,针对症状的锻炼计划,以及提高治疗依从性的策略。我们建立了质量指标,包括新入院患者100%的基线脂质检测和≥95%的异常及时干预率。以患者为中心的模式降低了心血管风险,改善了患者的预后,并为资源有限环境中的代谢健康管理提供了一种可扩展的方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Clinical management of lipid metabolism abnormalities induced by antipsychotics in closed psychiatric settings: challenges and integrated strategies.

In closed psychiatric settings, antipsychotic-induced lipid metabolism abnormalities pose significant clinical challenges. Constrained by limited patient mobility, fluctuating treatment adherence, and monotonous diets, traditional management struggles to adequately balance drug side effects with patient health needs. This study presents an integrated framework involving surveillance, intervention, and interdisciplinary collaboration. It includes a comprehensive "admission-to-intervention" monitoring system, low-glycemic diet combined with portion control, symptom-specific exercise programs, and strategies to improve treatment adherence. We establish quality metrics, including 100% baseline lipid testing for new admissions and ≥ 95% timely intervention rate for abnormalities. The patient-centered model reduces cardiovascular risks, improves patient outcomes, and offers a scalable approach for metabolic health management in resource-limited environments.

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来源期刊
Lipids in Health and Disease
Lipids in Health and Disease 生物-生化与分子生物学
CiteScore
7.70
自引率
2.20%
发文量
122
审稿时长
3-8 weeks
期刊介绍: Lipids in Health and Disease is an open access, peer-reviewed, journal that publishes articles on all aspects of lipids: their biochemistry, pharmacology, toxicology, role in health and disease, and the synthesis of new lipid compounds. Lipids in Health and Disease is aimed at all scientists, health professionals and physicians interested in the area of lipids. Lipids are defined here in their broadest sense, to include: cholesterol, essential fatty acids, saturated fatty acids, phospholipids, inositol lipids, second messenger lipids, enzymes and synthetic machinery that is involved in the metabolism of various lipids in the cells and tissues, and also various aspects of lipid transport, etc. In addition, the journal also publishes research that investigates and defines the role of lipids in various physiological processes, pathology and disease. In particular, the journal aims to bridge the gap between the bench and the clinic by publishing articles that are particularly relevant to human diseases and the role of lipids in the management of various diseases.
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