微生物引物：在治疗慢性多微生物感染的挑战和机遇-生态进化的观点。

IF 2.6 4区生物学 Q3 MICROBIOLOGY

Microbiology-Sgm Pub Date : 2025-06-01 DOI:10.1099/mic.0.001567

Jennifer M Farrell, Sam P Brown

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引用次数: 0

摘要

在这篇引语中，我们将回顾急性和慢性感染、单微生物感染和多微生物感染之间的关键区别，以及这些区别如何共同产生慢性多微生物感染日益严重的危机。慢性（非解决性）感染对全球人类健康造成了巨大且日益加重的负担。在介绍了慢性多微生物感染的基本特性之后，我们将从生态学和进化的角度来帮助概述这一领域的研究议程，指出改善感染预防、诊断和治疗的挑战和机遇。

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Microbial Primer: Challenges and opportunities in the treatment of chronic polymicrobial infections ‒ an eco-evolutionary perspective.

In this primer, we will review the key distinctions between acute and chronic infections, between mono- and polymicrobial infections and how these distinctions work together to generate the growing crisis of chronic polymicrobial infections. Chronic (non-resolving) infections place a large and growing burden on human health, globally. Following an introduction to the basic properties of chronic polymicrobial infections, we will use an ecological and evolutionary perspective to help outline a research agenda for this field, flagging both challenges and opportunities for improved infection prevention, diagnosis and treatment.

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来源期刊

Microbiology-Sgm 生物-微生物学

CiteScore

4.60

自引率

7.10%

发文量

132

审稿时长

3.0 months

期刊介绍： We publish high-quality original research on bacteria, fungi, protists, archaea, algae, parasites and other microscopic life forms. Topics include but are not limited to: Antimicrobials and antimicrobial resistance Bacteriology and parasitology Biochemistry and biophysics Biofilms and biological systems Biotechnology and bioremediation Cell biology and signalling Chemical biology Cross-disciplinary work Ecology and environmental microbiology Food microbiology Genetics Host–microbe interactions Microbial methods and techniques Microscopy and imaging Omics, including genomics, proteomics and metabolomics Physiology and metabolism Systems biology and synthetic biology The microbiome.