大剂量胰岛素与持续胰岛素输注治疗成人高钾血症:一个病例系列。

IF 0.6 Q3 MEDICINE, GENERAL & INTERNAL
SAGE Open Medical Case Reports Pub Date : 2025-06-18 eCollection Date: 2025-01-01 DOI:10.1177/2050313X251348368
Nicole King, Neil Martinson, Mmakwata Lesudi, Ebrahim Variava
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引用次数: 0

摘要

高钾血症是一种医学紧急情况,可能表现为一系列心脏传导异常,如果不及时处理,可能发展为心脏骤停。虽然标准管理通常包括开始使用胰岛素以降低血清钾,但最佳给药方案仍然存在争议。血钾超过正常上限超过1 mmol/L的患者通常需要重复常规管理以转移细胞内钾-通常每2至4小时一次。尽管伴有肾功能不全的患者需要透析,但在资源有限的情况下,透析的可用性有限。我们提出三个病例的症状性高钾血症成功管理与持续胰岛素输注,从而避免了透析的需要。这些病例强调了在不能立即获得透析的情况下,持续胰岛素输注作为纠正高钾血症的替代策略的潜在作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Bolus doses of insulin versus a continuous insulin infusion for treating hyperkalaemia in adults: A case series.

Hyperkalaemia is a medical emergency that may manifest with a spectrum of cardiac conduction abnormalities and, if not promptly managed, can progress to cardiac arrest. While standard management typically involves stat doses of insulin to lower serum potassium, the optimal dosing regimen remains controversial. Patients whose serum potassium exceeds the upper normal limit by more than 1 mmol/L often require repeated conventional management to shift potassium intracellularly - usually every 2 to 4 h. Although dialysis is indicated in patients with concomitant renal dysfunction, its availability in resource-constrained settings is limited. We present three cases of symptomatic hyperkalaemia successfully managed with continuous insulin infusions, thereby obviating the need for dialysis. These cases underscore the potential role of continuous insulin infusions as an alternative strategy for correcting hyperkalaemia in settings where dialysis is not immediately available.

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来源期刊
SAGE Open Medical Case Reports
SAGE Open Medical Case Reports MEDICINE, GENERAL & INTERNAL-
CiteScore
0.60
自引率
0.00%
发文量
320
审稿时长
8 weeks
期刊介绍: SAGE Open Medical Case Reports (indexed in PubMed Central) is a peer reviewed, open access journal. It aims to provide a publication home for short case reports and case series, which often do not find a place in traditional primary research journals, but provide key insights into real medical cases that are essential for physicians, and may ultimately help to improve patient outcomes. SAGE Open Medical Case Reports does not limit content due to page budgets or thematic significance. Papers are subject to rigorous peer review and are selected on the basis of whether the research is sound and deserves publication. By virtue of not restricting papers to a narrow discipline, SAGE Open Medical Case Reports facilitates the discovery of the connections between papers, whether within or between disciplines. Case reports can span the full spectrum of medicine across the health sciences in the broadest sense, including: Allergy/Immunology Anaesthesia/Pain Cardiovascular Critical Care/ Emergency Medicine Dentistry Dermatology Diabetes/Endocrinology Epidemiology/Public Health Gastroenterology/Hepatology Geriatrics/Gerontology Haematology Infectious Diseases Mental Health/Psychiatry Nephrology Neurology Nursing Obstetrics/Gynaecology Oncology Ophthalmology Orthopaedics/Rehabilitation/Occupational Therapy Otolaryngology Palliative Medicine Pathology Pharmacoeconomics/health economics Pharmacoepidemiology/Drug safety Psychopharmacology Radiology Respiratory Medicine Rheumatology/ Clinical Immunology Sports Medicine Surgery Toxicology Urology Women''s Health.
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