Mario Castillo-Sang, Matias Rios, Tom Wilkinson, Niem Khan, Masroor Alam, Sean Degrande, Prashant Nayak
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We summarize current surgical understanding of MAC and how it applies to endoscopic surgery through our experience.</p><p><strong>Methods: </strong>All patients with severe MAC undergoing endoscopic mitral surgery at a single institution (December 2020 to August 2024) were studied.</p><p><strong>Results: </strong>Twenty-five patients (3 female patients) with an average left ventricular ejection fraction of 52.12% (46.25% to 60%), average age of 69.13 (64 to 75.7) years, average body surface area of 1.92 (1.69 to 2.09) m<sup>2</sup>, and average Society of Thoracic Surgeons predicted risk of mortality score of 8.30% (2.13% to 8.66%) underwent endoscopic surgery. Twelve patients had regurgitation (48%), 10 had stenosis (48%), and 3 had a combination (12%). Circumferential MAC was found in 4 patients (16%), 80% circumference in 7 (28%), 60% circumference in 7 (28%), and 40% circumference in 7 (28%). Mitral valve replacement was done in 72% (<i>n</i> = 18) with tissue valves (<i>n</i> = 11), mechanical valves (<i>n</i> = 4), or transcatheter balloon-expandable valves (<i>n</i> = 3). Seven patients (28%) had repairs. There were no operative deaths, atrioventricular complications, or strokes. The average duration of surgery was 5 h 40 min (4 h 13 min to 8 h 22 min), with average cardiopulmonary bypass and cross-clamp times of 214 (166 to 241) min and 152 (117 to 193) min, respectively. MAC was debrided in 20 patients with ultrasonic emulsification (<i>n</i> = 13) or mechanical debridement (<i>n</i> = 7).</p><p><strong>Conclusions: </strong>Endoscopic surgery for severe MAC can be safely and successfully performed using a combination of surgical techniques including ultrasonic decalcification, mechanical debridement, annular patching, and direct implantation of balloon-expandable valves.</p>","PeriodicalId":13574,"journal":{"name":"Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery","volume":" ","pages":"15569845251348207"},"PeriodicalIF":1.6000,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Totally Endoscopic Management of Mitral Annular Calcification: A Single-Center Experience.\",\"authors\":\"Mario Castillo-Sang, Matias Rios, Tom Wilkinson, Niem Khan, Masroor Alam, Sean Degrande, Prashant Nayak\",\"doi\":\"10.1177/15569845251348207\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>Minimally invasive surgery for mitral annular calcification (MAC) has been reported sporadically, but data on endoscopic surgery are scarce. We summarize current surgical understanding of MAC and how it applies to endoscopic surgery through our experience.</p><p><strong>Methods: </strong>All patients with severe MAC undergoing endoscopic mitral surgery at a single institution (December 2020 to August 2024) were studied.</p><p><strong>Results: </strong>Twenty-five patients (3 female patients) with an average left ventricular ejection fraction of 52.12% (46.25% to 60%), average age of 69.13 (64 to 75.7) years, average body surface area of 1.92 (1.69 to 2.09) m<sup>2</sup>, and average Society of Thoracic Surgeons predicted risk of mortality score of 8.30% (2.13% to 8.66%) underwent endoscopic surgery. Twelve patients had regurgitation (48%), 10 had stenosis (48%), and 3 had a combination (12%). Circumferential MAC was found in 4 patients (16%), 80% circumference in 7 (28%), 60% circumference in 7 (28%), and 40% circumference in 7 (28%). 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引用次数: 0
摘要
目的:微创手术治疗二尖瓣环形钙化(MAC)的报道很少,但内窥镜手术的数据很少。我们总结了目前外科对MAC的理解,以及如何通过我们的经验将其应用于内窥镜手术。方法:对同一医院(2020年12月至2024年8月)接受内窥镜二尖瓣手术的所有重度MAC患者进行研究。结果:25例患者(女性3例)平均左心室射血分数52.12%(46.25% ~ 60%),平均年龄69.13(64 ~ 75.7)岁,平均体表面积1.92 (1.69 ~ 2.09)m2,平均胸外科医师预测死亡风险评分8.30%(2.13% ~ 8.66%)行内镜手术。返流12例(48%),狭窄10例(48%),合并3例(12%)。圆周型MAC 4例(16%),圆周型MAC 7例(28%),圆周型MAC 7例(28%),圆周型MAC 7例(60%),圆周型MAC 7例(28%)。72% (n = 18)的患者采用组织瓣膜(n = 11)、机械瓣膜(n = 4)或经导管球囊扩张瓣膜(n = 3)进行二尖瓣置换术。7例患者(28%)进行了修复。没有手术死亡、房室并发症或中风。平均手术时间为5 h 40 min (4 h 13 min ~ 8 h 22 min),平均体外循环和交叉夹持次数分别为214 (166 ~ 241)min和152 (117 ~ 193)min。20例患者采用超声乳化(n = 13)或机械清创(n = 7)进行MAC清创。结论:采用超声脱钙、机械清创、环形修补和球囊可膨胀瓣膜直接植入等手术技术,可以安全、成功地进行严重MAC的内镜手术。
Totally Endoscopic Management of Mitral Annular Calcification: A Single-Center Experience.
Objective: Minimally invasive surgery for mitral annular calcification (MAC) has been reported sporadically, but data on endoscopic surgery are scarce. We summarize current surgical understanding of MAC and how it applies to endoscopic surgery through our experience.
Methods: All patients with severe MAC undergoing endoscopic mitral surgery at a single institution (December 2020 to August 2024) were studied.
Results: Twenty-five patients (3 female patients) with an average left ventricular ejection fraction of 52.12% (46.25% to 60%), average age of 69.13 (64 to 75.7) years, average body surface area of 1.92 (1.69 to 2.09) m2, and average Society of Thoracic Surgeons predicted risk of mortality score of 8.30% (2.13% to 8.66%) underwent endoscopic surgery. Twelve patients had regurgitation (48%), 10 had stenosis (48%), and 3 had a combination (12%). Circumferential MAC was found in 4 patients (16%), 80% circumference in 7 (28%), 60% circumference in 7 (28%), and 40% circumference in 7 (28%). Mitral valve replacement was done in 72% (n = 18) with tissue valves (n = 11), mechanical valves (n = 4), or transcatheter balloon-expandable valves (n = 3). Seven patients (28%) had repairs. There were no operative deaths, atrioventricular complications, or strokes. The average duration of surgery was 5 h 40 min (4 h 13 min to 8 h 22 min), with average cardiopulmonary bypass and cross-clamp times of 214 (166 to 241) min and 152 (117 to 193) min, respectively. MAC was debrided in 20 patients with ultrasonic emulsification (n = 13) or mechanical debridement (n = 7).
Conclusions: Endoscopic surgery for severe MAC can be safely and successfully performed using a combination of surgical techniques including ultrasonic decalcification, mechanical debridement, annular patching, and direct implantation of balloon-expandable valves.
期刊介绍:
Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery is the first journal whose main mission is to disseminate information specifically about advances in technology and techniques that lead to less invasive treatment of cardiothoracic and vascular disease. It delivers cutting edge original research, reviews, essays, case reports, and editorials from the pioneers and experts in the field of minimally invasive cardiothoracic and vascular disease, including biomedical engineers. Also included are papers presented at the annual ISMICS meeting. Official Journal of the International Society for Minimally Invasive Cardiothoracic Surgery