Vishal Kumar , Deepika Kaushik , Harmandeep Kaur , Emel Oz , Charles Brennan , Charalampos Proestos , Fatih Oz , Mukul Kumar
{"title":"藻类在调节人体脂质谱中的作用,从代谢途径到生物技术应用","authors":"Vishal Kumar , Deepika Kaushik , Harmandeep Kaur , Emel Oz , Charles Brennan , Charalampos Proestos , Fatih Oz , Mukul Kumar","doi":"10.1016/j.algal.2025.104149","DOIUrl":null,"url":null,"abstract":"<div><div>Lipids are vital organic compounds that serve crucial functions in energy storage, cellular architecture, and signaling processes. Algal lipids rich in polyunsaturated fatty acids, particularly omega 3 and omega 6, have garnered attention for their purported advantages, including the resolution of inflammation, cardiovascular protection, and regulation of metabolism. This detailed investigation delves into the importance of lipids, especially those derived from algae. Their potential offers a valuable pathway for acquiring a wide range of crucial fatty acids and bioactive substances that may enhance human well-being. The manuscript explores the biosynthesis of algal lipids, detailing the related metabolic pathways and their potential integration to improve lipid profiles in humans. Moreover, the study highlights the mechanisms of lipid transport and metabolism in human systems, the relationship between algal lipids and gut microbiota, and the recent innovations in biotechnology focused on improving algal lipid production. This study further investigates their effectiveness in tackling neuroinflammation and metabolic disorders. In conclusion, the utilization of algae lipids and their incorporation into functional foods and nutraceuticals offers a promising alternative to current techniques for sourcing PUFAs, underscoring their significance in modern dietary habits.</div></div>","PeriodicalId":7855,"journal":{"name":"Algal Research-Biomass Biofuels and Bioproducts","volume":"90 ","pages":"Article 104149"},"PeriodicalIF":4.5000,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Role of algae in modulating human lipid profiles from metabolic pathways to biotechnological applications\",\"authors\":\"Vishal Kumar , Deepika Kaushik , Harmandeep Kaur , Emel Oz , Charles Brennan , Charalampos Proestos , Fatih Oz , Mukul Kumar\",\"doi\":\"10.1016/j.algal.2025.104149\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Lipids are vital organic compounds that serve crucial functions in energy storage, cellular architecture, and signaling processes. Algal lipids rich in polyunsaturated fatty acids, particularly omega 3 and omega 6, have garnered attention for their purported advantages, including the resolution of inflammation, cardiovascular protection, and regulation of metabolism. This detailed investigation delves into the importance of lipids, especially those derived from algae. Their potential offers a valuable pathway for acquiring a wide range of crucial fatty acids and bioactive substances that may enhance human well-being. The manuscript explores the biosynthesis of algal lipids, detailing the related metabolic pathways and their potential integration to improve lipid profiles in humans. Moreover, the study highlights the mechanisms of lipid transport and metabolism in human systems, the relationship between algal lipids and gut microbiota, and the recent innovations in biotechnology focused on improving algal lipid production. This study further investigates their effectiveness in tackling neuroinflammation and metabolic disorders. In conclusion, the utilization of algae lipids and their incorporation into functional foods and nutraceuticals offers a promising alternative to current techniques for sourcing PUFAs, underscoring their significance in modern dietary habits.</div></div>\",\"PeriodicalId\":7855,\"journal\":{\"name\":\"Algal Research-Biomass Biofuels and Bioproducts\",\"volume\":\"90 \",\"pages\":\"Article 104149\"},\"PeriodicalIF\":4.5000,\"publicationDate\":\"2025-06-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Algal Research-Biomass Biofuels and Bioproducts\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2211926425002607\",\"RegionNum\":2,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"BIOTECHNOLOGY & APPLIED MICROBIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Algal Research-Biomass Biofuels and Bioproducts","FirstCategoryId":"99","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2211926425002607","RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"BIOTECHNOLOGY & APPLIED MICROBIOLOGY","Score":null,"Total":0}
Role of algae in modulating human lipid profiles from metabolic pathways to biotechnological applications
Lipids are vital organic compounds that serve crucial functions in energy storage, cellular architecture, and signaling processes. Algal lipids rich in polyunsaturated fatty acids, particularly omega 3 and omega 6, have garnered attention for their purported advantages, including the resolution of inflammation, cardiovascular protection, and regulation of metabolism. This detailed investigation delves into the importance of lipids, especially those derived from algae. Their potential offers a valuable pathway for acquiring a wide range of crucial fatty acids and bioactive substances that may enhance human well-being. The manuscript explores the biosynthesis of algal lipids, detailing the related metabolic pathways and their potential integration to improve lipid profiles in humans. Moreover, the study highlights the mechanisms of lipid transport and metabolism in human systems, the relationship between algal lipids and gut microbiota, and the recent innovations in biotechnology focused on improving algal lipid production. This study further investigates their effectiveness in tackling neuroinflammation and metabolic disorders. In conclusion, the utilization of algae lipids and their incorporation into functional foods and nutraceuticals offers a promising alternative to current techniques for sourcing PUFAs, underscoring their significance in modern dietary habits.
期刊介绍:
Algal Research is an international phycology journal covering all areas of emerging technologies in algae biology, biomass production, cultivation, harvesting, extraction, bioproducts, biorefinery, engineering, and econometrics. Algae is defined to include cyanobacteria, microalgae, and protists and symbionts of interest in biotechnology. The journal publishes original research and reviews for the following scope: algal biology, including but not exclusive to: phylogeny, biodiversity, molecular traits, metabolic regulation, and genetic engineering, algal cultivation, e.g. phototrophic systems, heterotrophic systems, and mixotrophic systems, algal harvesting and extraction systems, biotechnology to convert algal biomass and components into biofuels and bioproducts, e.g., nutraceuticals, pharmaceuticals, animal feed, plastics, etc. algal products and their economic assessment