Jianrui Ma , Peijian Wei , Fengwen Zhang , Junke Chang , Manchen Gao , Chuangshi Wang , Xiaofang Yan , Cheng Wang , Shouzheng Wang , Yongquan Xie , Fang Fang , Xiangbin Pan
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The propensity score matching (PSM) method was performed as a sensitivity analysis.</div></div><div><h3>Results</h3><div>As defined by Mitral Valve Academic Research Consortium, the 30-day major adverse events, technical success, device success, and procedural success in the Echo guidance group were 5.31 %, 97.3 %, 89.4 %, and 88.5 %, similar to 8.64 %, 96.3 %, 85.2 %, and 84.0 % in the Co-guidance group, respectively (<em>p</em> > 0.05). Significant MR reduction and improvements in New York Heart Association functional class were observed in both groups (<em>p</em> < 0.05). The 1-year freedom from all-cause mortality and a composite of all-cause mortality and heart failure hospitalization were 94.5 % (95 % confidence interval (CI), 89.8 %–99.4 %) and 90.1 % (95 % CI, 83.6 %–97.2 %) in the Echo guidance group, similar to 92.1 % (95 % CI, 86.3 %–98.4 %) and 88.4 % (95 % CI, 81.6 %–95.9 %) in the Co-guidance group, respectively (<em>p</em> > 0.05). PSM-cohort analysis confirmed these findings.</div></div><div><h3>Conclusions</h3><div>The simplified M-TEER procedure under full echocardiographic guidance showed comparable outcomes to the traditional procedure under echocardiographic and fluoroscopic co-guidance.</div></div>","PeriodicalId":38026,"journal":{"name":"IJC Heart and Vasculature","volume":"59 ","pages":"Article 101730"},"PeriodicalIF":2.5000,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Procedural simplification in mitral valve transcatheter edge-to-edge repair: full echocardiographic guidance and outcomes\",\"authors\":\"Jianrui Ma , Peijian Wei , Fengwen Zhang , Junke Chang , Manchen Gao , Chuangshi Wang , Xiaofang Yan , Cheng Wang , Shouzheng Wang , Yongquan Xie , Fang Fang , Xiangbin Pan\",\"doi\":\"10.1016/j.ijcha.2025.101730\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><div>Our group pioneered attempts to simplify the mitral valve transcatheter edge-to-edge repair (M-TEER) procedure under full echocardiographic guidance; however, its safety and effectiveness remain unclear. This study aimed to compare its outcome with the traditional procedure under echocardiographic and fluoroscopic co-guidance.</div></div><div><h3>Methods</h3><div>From Jan 2021 to May 2024, 194 mitral regurgitation (MR) patients undergoing the simplified procedure (Echo guidance group, n = 113) and the traditional procedure (Co-guidance group, n = 81) were retrospectively reviewed. The propensity score matching (PSM) method was performed as a sensitivity analysis.</div></div><div><h3>Results</h3><div>As defined by Mitral Valve Academic Research Consortium, the 30-day major adverse events, technical success, device success, and procedural success in the Echo guidance group were 5.31 %, 97.3 %, 89.4 %, and 88.5 %, similar to 8.64 %, 96.3 %, 85.2 %, and 84.0 % in the Co-guidance group, respectively (<em>p</em> > 0.05). Significant MR reduction and improvements in New York Heart Association functional class were observed in both groups (<em>p</em> < 0.05). The 1-year freedom from all-cause mortality and a composite of all-cause mortality and heart failure hospitalization were 94.5 % (95 % confidence interval (CI), 89.8 %–99.4 %) and 90.1 % (95 % CI, 83.6 %–97.2 %) in the Echo guidance group, similar to 92.1 % (95 % CI, 86.3 %–98.4 %) and 88.4 % (95 % CI, 81.6 %–95.9 %) in the Co-guidance group, respectively (<em>p</em> > 0.05). PSM-cohort analysis confirmed these findings.</div></div><div><h3>Conclusions</h3><div>The simplified M-TEER procedure under full echocardiographic guidance showed comparable outcomes to the traditional procedure under echocardiographic and fluoroscopic co-guidance.</div></div>\",\"PeriodicalId\":38026,\"journal\":{\"name\":\"IJC Heart and Vasculature\",\"volume\":\"59 \",\"pages\":\"Article 101730\"},\"PeriodicalIF\":2.5000,\"publicationDate\":\"2025-06-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"IJC Heart and Vasculature\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2352906725001332\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"CARDIAC & CARDIOVASCULAR SYSTEMS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"IJC Heart and Vasculature","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2352906725001332","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
Procedural simplification in mitral valve transcatheter edge-to-edge repair: full echocardiographic guidance and outcomes
Background
Our group pioneered attempts to simplify the mitral valve transcatheter edge-to-edge repair (M-TEER) procedure under full echocardiographic guidance; however, its safety and effectiveness remain unclear. This study aimed to compare its outcome with the traditional procedure under echocardiographic and fluoroscopic co-guidance.
Methods
From Jan 2021 to May 2024, 194 mitral regurgitation (MR) patients undergoing the simplified procedure (Echo guidance group, n = 113) and the traditional procedure (Co-guidance group, n = 81) were retrospectively reviewed. The propensity score matching (PSM) method was performed as a sensitivity analysis.
Results
As defined by Mitral Valve Academic Research Consortium, the 30-day major adverse events, technical success, device success, and procedural success in the Echo guidance group were 5.31 %, 97.3 %, 89.4 %, and 88.5 %, similar to 8.64 %, 96.3 %, 85.2 %, and 84.0 % in the Co-guidance group, respectively (p > 0.05). Significant MR reduction and improvements in New York Heart Association functional class were observed in both groups (p < 0.05). The 1-year freedom from all-cause mortality and a composite of all-cause mortality and heart failure hospitalization were 94.5 % (95 % confidence interval (CI), 89.8 %–99.4 %) and 90.1 % (95 % CI, 83.6 %–97.2 %) in the Echo guidance group, similar to 92.1 % (95 % CI, 86.3 %–98.4 %) and 88.4 % (95 % CI, 81.6 %–95.9 %) in the Co-guidance group, respectively (p > 0.05). PSM-cohort analysis confirmed these findings.
Conclusions
The simplified M-TEER procedure under full echocardiographic guidance showed comparable outcomes to the traditional procedure under echocardiographic and fluoroscopic co-guidance.
期刊介绍:
IJC Heart & Vasculature is an online-only, open-access journal dedicated to publishing original articles and reviews (also Editorials and Letters to the Editor) which report on structural and functional cardiovascular pathology, with an emphasis on imaging and disease pathophysiology. Articles must be authentic, educational, clinically relevant, and original in their content and scientific approach. IJC Heart & Vasculature requires the highest standards of scientific integrity in order to promote reliable, reproducible and verifiable research findings. All authors are advised to consult the Principles of Ethical Publishing in the International Journal of Cardiology before submitting a manuscript. Submission of a manuscript to this journal gives the publisher the right to publish that paper if it is accepted. Manuscripts may be edited to improve clarity and expression.