Biagio Pinchera, Rosa Carrano, Elisa Schettino, Alessia D'Agostino, Emilia Trucillo, Federica Cuccurullo, Fabrizio Salemi, Amerigo Piccione, Ivan Gentile
{"title":"住院肾移植患者的尿路感染:真实的经历。","authors":"Biagio Pinchera, Rosa Carrano, Elisa Schettino, Alessia D'Agostino, Emilia Trucillo, Federica Cuccurullo, Fabrizio Salemi, Amerigo Piccione, Ivan Gentile","doi":"10.5500/wjt.v15.i2.99554","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Urinary tract infections (UTIs) in kidney transplant patients are a challenge.</p><p><strong>Aim: </strong>To evaluate epidemiology, clinical status, therapeutic management, and clinical outcome of kidney transplant patients in a university hospital for UTI.</p><p><strong>Methods: </strong>We conducted a retrospective observational study, enrolling all kidney transplant patients hospitalized for UTI, with the objective to evaluate the epidemiology, clinical status, therapeutic management, and clinical outcome of kidney transplant patients.</p><p><strong>Results: </strong>From our real-life experience, infection with multidrug-resistant germs was confirmed as a risk factor for the severe evolution of the infection. At the same time, the re-evaluation of immunosuppressive therapy could be an important therapeutic strategy in the course of infection.</p><p><strong>Conclusion: </strong>Prompt initiation of empiric antibiotic therapy upon initiation of microbiological investigations may reduce the risk of severe infection progression.</p>","PeriodicalId":65557,"journal":{"name":"世界移植杂志","volume":"15 2","pages":"99554"},"PeriodicalIF":0.0000,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11886297/pdf/","citationCount":"0","resultStr":"{\"title\":\"Urinary tract infections in kidney transplant patients admitted to hospital: A real-life experience.\",\"authors\":\"Biagio Pinchera, Rosa Carrano, Elisa Schettino, Alessia D'Agostino, Emilia Trucillo, Federica Cuccurullo, Fabrizio Salemi, Amerigo Piccione, Ivan Gentile\",\"doi\":\"10.5500/wjt.v15.i2.99554\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Urinary tract infections (UTIs) in kidney transplant patients are a challenge.</p><p><strong>Aim: </strong>To evaluate epidemiology, clinical status, therapeutic management, and clinical outcome of kidney transplant patients in a university hospital for UTI.</p><p><strong>Methods: </strong>We conducted a retrospective observational study, enrolling all kidney transplant patients hospitalized for UTI, with the objective to evaluate the epidemiology, clinical status, therapeutic management, and clinical outcome of kidney transplant patients.</p><p><strong>Results: </strong>From our real-life experience, infection with multidrug-resistant germs was confirmed as a risk factor for the severe evolution of the infection. At the same time, the re-evaluation of immunosuppressive therapy could be an important therapeutic strategy in the course of infection.</p><p><strong>Conclusion: </strong>Prompt initiation of empiric antibiotic therapy upon initiation of microbiological investigations may reduce the risk of severe infection progression.</p>\",\"PeriodicalId\":65557,\"journal\":{\"name\":\"世界移植杂志\",\"volume\":\"15 2\",\"pages\":\"99554\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-06-18\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11886297/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"世界移植杂志\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.5500/wjt.v15.i2.99554\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"世界移植杂志","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.5500/wjt.v15.i2.99554","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Urinary tract infections in kidney transplant patients admitted to hospital: A real-life experience.
Background: Urinary tract infections (UTIs) in kidney transplant patients are a challenge.
Aim: To evaluate epidemiology, clinical status, therapeutic management, and clinical outcome of kidney transplant patients in a university hospital for UTI.
Methods: We conducted a retrospective observational study, enrolling all kidney transplant patients hospitalized for UTI, with the objective to evaluate the epidemiology, clinical status, therapeutic management, and clinical outcome of kidney transplant patients.
Results: From our real-life experience, infection with multidrug-resistant germs was confirmed as a risk factor for the severe evolution of the infection. At the same time, the re-evaluation of immunosuppressive therapy could be an important therapeutic strategy in the course of infection.
Conclusion: Prompt initiation of empiric antibiotic therapy upon initiation of microbiological investigations may reduce the risk of severe infection progression.