AKT Signals by Infrared Light in Cancer.

Cancer cells are a complex and robust system dynamically interconnected by the signaling genes network through the up-regulated AKT gene. How signals are transmitted still is not clear. The hyperphosphorylated AKT locus during protein-protein interaction sends infrared (IR) light as a signal to the other molecules and cells for cancer proliferation, migration, and angiogenesis. The hyperactivated AKT locus in cancer transmits IR light with a wavelength different from that in normal cells that is mechanistically characteristic of AKT-mediated control of cancer, recommended for targeting therapy by IR resonance. Thus, signaling is achieved by IR light. Such signaling is the first response of the hyperactivated AKT gene, far ahead of any biochemical response, activating the interactome network and creating a robust cancer system.