Jeni Elizabeth Mathew, Atanu Kumar Pal, Thekke Adiyat Kishore
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Data of all patients, including patient demographic details, tumor characteristics including size, location, pre- and postoperative blood investigations, intraoperative findings, blood loss, postoperative course, complications, and follow-up of 6 months duration, were recorded. <b><i>Results:</i></b> The mean age of the study population was 52.62 ± 13.31 years, and the mean nephrometry score was 6.64 ± 1.91. The Veriset patch application failed in three patients (6.97%) and cortical renorrhaphy had to be performed for hemostasis. The Veriset group (VG) had significantly less console time and WIT when compared with renorrhaphy group (RG) (82.02 ± 25.17 minutes and 11.95 ± 10.02 minutes, respectively, <i>vs</i> 95.53 ± 29.80 minutes and 17.63 ± 6.59 minutes; <i>p</i> = 0.014 and <i>p</i> < 0.001, respectively). The RG witnessed a significant reduction in estimated glomerular filtration rate (eGFR) on postoperative day 1 as opposed to VG (-7.56 ± 15.89 mL/min/1.73 m<sup>2</sup> <i>vs</i> -0.21 ± 11.12 mL/min/1.73 m<sup>2</sup>; <i>p</i> = 0.015). The intraoperative blood loss, need for blood transfusion, postoperative change in hemoglobin rates, readmission, and renal function at 6 months in the VG and RG were comparable. <b><i>Conclusions:</i></b> The Veriset application instead of renorrhaphy led to reduced WIT, decreased console time, and early return of renal function with no significantly increased rate of complications.</p>","PeriodicalId":15723,"journal":{"name":"Journal of endourology","volume":" ","pages":""},"PeriodicalIF":2.9000,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"\\\"Partial Nephrectomy with Veriset: A Renorrhaphy-Less Approach\\\".\",\"authors\":\"Jeni Elizabeth Mathew, Atanu Kumar Pal, Thekke Adiyat Kishore\",\"doi\":\"10.1089/end.2024.0844\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p><b><i>Introduction and Objectives:</i></b> Renorrhaphy during partial nephrectomy is technically challenging and can extend the warm ischemia time (WIT). This study investigates the use of Veriset™ as an alternative to renorrhaphy in robot-assisted partial nephrectomy (RAPN) and presents our findings. <b><i>Methods:</i></b> In this retrospective analysis, 43 patients who had Veriset patch placed on the tumor bed post resection were compared against 43 patients who underwent conventional single-layer renorrhaphy for RAPN from January 2023 to January 2024 at our institution. The two groups underwent propensity score matching based on age, body mass index, and R.E.N.A.L. nephrometry score. Data of all patients, including patient demographic details, tumor characteristics including size, location, pre- and postoperative blood investigations, intraoperative findings, blood loss, postoperative course, complications, and follow-up of 6 months duration, were recorded. <b><i>Results:</i></b> The mean age of the study population was 52.62 ± 13.31 years, and the mean nephrometry score was 6.64 ± 1.91. The Veriset patch application failed in three patients (6.97%) and cortical renorrhaphy had to be performed for hemostasis. The Veriset group (VG) had significantly less console time and WIT when compared with renorrhaphy group (RG) (82.02 ± 25.17 minutes and 11.95 ± 10.02 minutes, respectively, <i>vs</i> 95.53 ± 29.80 minutes and 17.63 ± 6.59 minutes; <i>p</i> = 0.014 and <i>p</i> < 0.001, respectively). The RG witnessed a significant reduction in estimated glomerular filtration rate (eGFR) on postoperative day 1 as opposed to VG (-7.56 ± 15.89 mL/min/1.73 m<sup>2</sup> <i>vs</i> -0.21 ± 11.12 mL/min/1.73 m<sup>2</sup>; <i>p</i> = 0.015). 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引用次数: 0
摘要
前言与目的:肾部分切除术后的再修复在技术上具有挑战性,并且会延长热缺血时间(WIT)。本研究探讨了在机器人辅助部分肾切除术(RAPN)中使用Veriset™作为修复术的替代方案,并介绍了我们的研究结果。方法:回顾性分析我院2023年1月至2024年1月,43例肿瘤床上放置Veriset贴片的患者与43例常规单层重建的RAPN患者进行比较。两组患者根据年龄、体重指数和R.E.N.A.L.肾测量评分进行倾向评分匹配。记录所有患者的资料,包括患者人口统计学细节、肿瘤特征(包括大小、位置、术前和术后血液调查、术中发现、出血量、术后病程、并发症和随访6个月时间。结果:研究人群平均年龄为52.62±13.31岁,平均肾测量评分为6.64±1.91。3例患者(6.97%)使用Veriset贴片失败,必须进行皮质再缝合止血。Veriset组(VG)与RG组(分别为(82.02±25.17)min和(11.95±10.02)min,分别为(95.53±29.80)min和(17.63±6.59)min;P = 0.014, P < 0.001)。与VG组相比,RG组术后第1天肾小球滤过率(eGFR)显著降低(-7.56±15.89 mL/min/1.73 m2 vs -0.21±11.12 mL/min/1.73 m2;P = 0.015)。术中出血量、输血需求、术后血红蛋白率变化、再入院率和6个月时VG组和RG组的肾功能相当。结论:使用Veriset代替肾再缝合可减少WIT,缩短缓解时间,早期恢复肾功能,且并发症发生率无明显增加。
"Partial Nephrectomy with Veriset: A Renorrhaphy-Less Approach".
Introduction and Objectives: Renorrhaphy during partial nephrectomy is technically challenging and can extend the warm ischemia time (WIT). This study investigates the use of Veriset™ as an alternative to renorrhaphy in robot-assisted partial nephrectomy (RAPN) and presents our findings. Methods: In this retrospective analysis, 43 patients who had Veriset patch placed on the tumor bed post resection were compared against 43 patients who underwent conventional single-layer renorrhaphy for RAPN from January 2023 to January 2024 at our institution. The two groups underwent propensity score matching based on age, body mass index, and R.E.N.A.L. nephrometry score. Data of all patients, including patient demographic details, tumor characteristics including size, location, pre- and postoperative blood investigations, intraoperative findings, blood loss, postoperative course, complications, and follow-up of 6 months duration, were recorded. Results: The mean age of the study population was 52.62 ± 13.31 years, and the mean nephrometry score was 6.64 ± 1.91. The Veriset patch application failed in three patients (6.97%) and cortical renorrhaphy had to be performed for hemostasis. The Veriset group (VG) had significantly less console time and WIT when compared with renorrhaphy group (RG) (82.02 ± 25.17 minutes and 11.95 ± 10.02 minutes, respectively, vs 95.53 ± 29.80 minutes and 17.63 ± 6.59 minutes; p = 0.014 and p < 0.001, respectively). The RG witnessed a significant reduction in estimated glomerular filtration rate (eGFR) on postoperative day 1 as opposed to VG (-7.56 ± 15.89 mL/min/1.73 m2vs -0.21 ± 11.12 mL/min/1.73 m2; p = 0.015). The intraoperative blood loss, need for blood transfusion, postoperative change in hemoglobin rates, readmission, and renal function at 6 months in the VG and RG were comparable. Conclusions: The Veriset application instead of renorrhaphy led to reduced WIT, decreased console time, and early return of renal function with no significantly increased rate of complications.
期刊介绍:
Journal of Endourology, JE Case Reports, and Videourology are the leading peer-reviewed journal, case reports publication, and innovative videojournal companion covering all aspects of minimally invasive urology research, applications, and clinical outcomes.
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