S V Vtorushin, Z A Yurmazov, D M Loos, N V Vasilyev, N V Krakhmal
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Solitary fibrous tumor is a rare mesenchymal neoplasm, the most common localization of which is the pleural cavity, but the tumor can also affect other organs. This neoplasm with localisation in the kidney was first described only in 1996. Solitary fibrous tumor accounts for 0.2% of all kidney neoplasms and is an exceptional phenomenon. Currently, there is no generally accepted theory explaining the etiology and pathogenesis, probably, its development is a multifactorial process including a combination of genetic, epigenetic and external factors. Despite the lack of unambiguous opinion on the nature of the neoplasm, the spectrum of molecular abnormalities in this tumor has been sufficiently studied. The literature presents a limited number of publications devoted to this pathology, in this regard it should be noted that in routine practice, the morphological picture may not always be so unambiguous and require the pathologist to conduct differential diagnostics with a fairly wide range of tumors. Given the rarity of this disease, we would like to share a description of our own clinical observation demonstrating the possible difficulties of morphology diagnostics.
期刊介绍:
The journal deals with original investigations on pressing problems of general pathology and pathologic anatomy, newest research methods, major issues of the theory and practice as well as problems of experimental, comparative and geographic pathology. To inform readers latest achievements of Russian and foreign medicine the journal regularly publishes editorial and survey articles, reviews of the most interesting Russian and foreign books on pathologic anatomy, new data on modern methods of investigation (histochemistry, electron microscopy, autoradiography, etc.), about problems of teaching, articles on the history of pathological anatomy development both in Russia and abroad.