[肾脏孤立的纤维性肿瘤]。

Q4 Medicine
S V Vtorushin, Z A Yurmazov, D M Loos, N V Vasilyev, N V Krakhmal
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引用次数: 0

摘要

孤立性纤维性肿瘤是一种罕见的间质肿瘤,其最常见的定位是胸膜腔,但肿瘤也可影响其他器官。仅在1996年才首次报道了这种局部发生于肾脏的肿瘤。孤立性纤维性肿瘤占所有肾肿瘤的0.2%,是一种罕见的现象。目前,对其病因和发病机制还没有一个普遍接受的理论,其发展可能是一个多因素的过程,包括遗传、表观遗传和外部因素的共同作用。尽管缺乏对肿瘤性质的明确意见,但该肿瘤的分子异常谱已得到充分研究。文献介绍了有限数量的出版物,专门研究这种病理学,在这方面,应该注意的是,在常规实践中,形态学图像可能并不总是如此明确,需要病理学家对相当广泛的肿瘤进行鉴别诊断。鉴于这种疾病的罕见性,我们想分享我们自己的临床观察的描述,证明形态学诊断可能存在的困难。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Solitary fibrous tumor of the kidney].

Solitary fibrous tumor is a rare mesenchymal neoplasm, the most common localization of which is the pleural cavity, but the tumor can also affect other organs. This neoplasm with localisation in the kidney was first described only in 1996. Solitary fibrous tumor accounts for 0.2% of all kidney neoplasms and is an exceptional phenomenon. Currently, there is no generally accepted theory explaining the etiology and pathogenesis, probably, its development is a multifactorial process including a combination of genetic, epigenetic and external factors. Despite the lack of unambiguous opinion on the nature of the neoplasm, the spectrum of molecular abnormalities in this tumor has been sufficiently studied. The literature presents a limited number of publications devoted to this pathology, in this regard it should be noted that in routine practice, the morphological picture may not always be so unambiguous and require the pathologist to conduct differential diagnostics with a fairly wide range of tumors. Given the rarity of this disease, we would like to share a description of our own clinical observation demonstrating the possible difficulties of morphology diagnostics.

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来源期刊
Arkhiv patologii
Arkhiv patologii Medicine-Pathology and Forensic Medicine
CiteScore
0.90
自引率
0.00%
发文量
55
期刊介绍: The journal deals with original investigations on pressing problems of general pathology and pathologic anatomy, newest research methods, major issues of the theory and practice as well as problems of experimental, comparative and geographic pathology. To inform readers latest achievements of Russian and foreign medicine the journal regularly publishes editorial and survey articles, reviews of the most interesting Russian and foreign books on pathologic anatomy, new data on modern methods of investigation (histochemistry, electron microscopy, autoradiography, etc.), about problems of teaching, articles on the history of pathological anatomy development both in Russia and abroad.
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