最近的研究进展揭示了金属团在群体感应、抗菌活性和镧系元素获取方面的功能

IF 6.9 2区生物学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

Current Opinion in Chemical Biology Pub Date : 2025-06-19 DOI:10.1016/j.cbpa.2025.102604

Ghazal Kamyabi, Erica L. Debley, Elizabeth M. Nolan

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引用次数: 0

摘要

金属细胞是细菌、真菌和其他生物产生的金属螯合次生代谢物，用于从环境中获取必需的金属营养素。这篇综述重点介绍了该领域的一些最新发现：yersinabactin在群体感应中的作用，曲霉酰胺A抑制细菌Ni摄取的能力，以及甲基孤胺素的鉴定，甲基孤胺素是一种新的金属分子，可以使细菌获得镧系元素。

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Recent advances in metallophore research uncover functions in quorum sensing, antimicrobial activity, and lanthanide acquisition

Metallophores are metal-chelating secondary metabolites that bacteria, fungi, and other organisms produce to acquire essential metal nutrients from their environment. This review highlights some recent discoveries in the field: the role of yersiniabactin in quorum sensing, the capacity of aspergillomarasmine A to inhibit bacterial Ni uptake, and the identification of methylolanthanin, a novel metallophore that enables bacterial lanthanide acquisition.

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来源期刊

Current Opinion in Chemical Biology 生物-生化与分子生物学

CiteScore

13.30

自引率

1.30%

发文量

113

审稿时长

74 days

期刊介绍： COCHBI (Current Opinion in Chemical Biology) is a systematic review journal designed to offer specialists a unique and educational platform. Its goal is to help professionals stay informed about the growing volume of information in the field of Chemical Biology through systematic reviews.