无声真菌侵袭:免疫功能正常的老年患者发生曲霉菌性脑脓肿1例。

IF 1 Q3 MEDICINE, GENERAL & INTERNAL
Cureus Pub Date : 2025-06-15 eCollection Date: 2025-06-01 DOI:10.7759/cureus.86084
Jamie Therese Abad, Amanda Darzi, Kashmira Wani, Jasmine Omar
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引用次数: 0

摘要

由真菌病原体引起的脑脓肿在免疫正常的个体中并不常见。84岁男性,表现为发热、头痛。脑成像发现非特异性右额叶病变。两周后,他返回时症状恶化,意识不清,磁共振成像(MRI)显示多发脓肿,环形强化。手术切除和引流标本培养出曲霉。尽管进行了抗真菌治疗,他的神经系统状况还是有所好转。该病例强调了在患有非特异性脑病变的老年患者中考虑真菌病原体的重要性,即使没有局灶性神经系统症状或原发感染的证据。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Silent Fungal Invasion: A Case of Aspergillus Brain Abscesses in an Immunocompetent Older Adult Patient.

Brain abscesses caused by fungal pathogens are uncommon in immunocompetent individuals. An 84-year-old man presented with fever and headache. Brain imaging identified a nonspecific right frontal lesion. He returned with worsening symptoms and confusion after two weeks, with magnetic resonance imaging (MRI) revealing multiple abscesses with ring enhancement. Cultures from surgical resection and drainage samples grew Aspergillus. Despite antifungal therapy, his neurological condition declined. This case highlights the importance of considering fungal pathogens in older patients with nonspecific brain lesions, even without focal neurological symptoms or evidence of a primary infection.

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