{"title":"减少中央静脉相关血流感染的新生儿重症监护病房特异性捆绑：干预措施的比较医疗成本。","authors":"Irem Iyigun, Kubra Aykac, Pınar Basar, Zeynep Buyukgullu, Sibel Durak, Hasan Tolga Celik, Sule Yigit, Yasemin Ozsurekci","doi":"10.1016/j.ajic.2025.06.010","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Central line-associated bloodstream infections (CLABSIs) in neonatal intensive care units (NICUs) significantly impact patient outcomes and health care costs. This study evaluates the effect of NICU-specific bundle designed to prevent CLABSIs.</p><p><strong>Methods: </strong>This retrospective single-center study was conducted at Hacettepe University Faculty of Medicine from March 2020 to August 2021. It was designed to compare 2 periods: pre-intervention and post-intervention period.</p><p><strong>Results: </strong>The implementation of the bundles led to a significant reduction in infection rates, with CLABSIs decreasing from 29 to 4 per 1,000 central line days in NICU-1 and from 14.2 to 2.6 per 1,000 central line days in NICU-2. This decline was accompanied by an 80% reduction in the average health care cost per patient.</p><p><strong>Conclusions: </strong>The implementation of a NICU-specific CLABSI prevention bundle significantly reduced infection rates and lowered health care costs by approximately 80% per patient. These findings highlight the effectiveness of structured, multidisciplinary infection control strategies in improving neonatal outcomes and resource utilization.</p>","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":" ","pages":""},"PeriodicalIF":2.4000,"publicationDate":"2025-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"NICU-specific bundle for minimizing central line-associated bloodstream infections: Comparative health care costs of interventions.\",\"authors\":\"Irem Iyigun, Kubra Aykac, Pınar Basar, Zeynep Buyukgullu, Sibel Durak, Hasan Tolga Celik, Sule Yigit, Yasemin Ozsurekci\",\"doi\":\"10.1016/j.ajic.2025.06.010\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Central line-associated bloodstream infections (CLABSIs) in neonatal intensive care units (NICUs) significantly impact patient outcomes and health care costs. This study evaluates the effect of NICU-specific bundle designed to prevent CLABSIs.</p><p><strong>Methods: </strong>This retrospective single-center study was conducted at Hacettepe University Faculty of Medicine from March 2020 to August 2021. It was designed to compare 2 periods: pre-intervention and post-intervention period.</p><p><strong>Results: </strong>The implementation of the bundles led to a significant reduction in infection rates, with CLABSIs decreasing from 29 to 4 per 1,000 central line days in NICU-1 and from 14.2 to 2.6 per 1,000 central line days in NICU-2. This decline was accompanied by an 80% reduction in the average health care cost per patient.</p><p><strong>Conclusions: </strong>The implementation of a NICU-specific CLABSI prevention bundle significantly reduced infection rates and lowered health care costs by approximately 80% per patient. These findings highlight the effectiveness of structured, multidisciplinary infection control strategies in improving neonatal outcomes and resource utilization.</p>\",\"PeriodicalId\":7621,\"journal\":{\"name\":\"American journal of infection control\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":2.4000,\"publicationDate\":\"2025-06-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"American journal of infection control\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1016/j.ajic.2025.06.010\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"INFECTIOUS DISEASES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"American journal of infection control","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.ajic.2025.06.010","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"INFECTIOUS DISEASES","Score":null,"Total":0}
NICU-specific bundle for minimizing central line-associated bloodstream infections: Comparative health care costs of interventions.
Background: Central line-associated bloodstream infections (CLABSIs) in neonatal intensive care units (NICUs) significantly impact patient outcomes and health care costs. This study evaluates the effect of NICU-specific bundle designed to prevent CLABSIs.
Methods: This retrospective single-center study was conducted at Hacettepe University Faculty of Medicine from March 2020 to August 2021. It was designed to compare 2 periods: pre-intervention and post-intervention period.
Results: The implementation of the bundles led to a significant reduction in infection rates, with CLABSIs decreasing from 29 to 4 per 1,000 central line days in NICU-1 and from 14.2 to 2.6 per 1,000 central line days in NICU-2. This decline was accompanied by an 80% reduction in the average health care cost per patient.
Conclusions: The implementation of a NICU-specific CLABSI prevention bundle significantly reduced infection rates and lowered health care costs by approximately 80% per patient. These findings highlight the effectiveness of structured, multidisciplinary infection control strategies in improving neonatal outcomes and resource utilization.
期刊介绍：
AJIC covers key topics and issues in infection control and epidemiology. Infection control professionals, including physicians, nurses, and epidemiologists, rely on AJIC for peer-reviewed articles covering clinical topics as well as original research. As the official publication of the Association for Professionals in Infection Control and Epidemiology (APIC)
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