cucl介导的二硫代氨基甲酸三乙胺盐的脱硫反应：2-氨基恶唑啉和硫脲的获得及其合成应用

IF 1.5 4区化学 Q3 CHEMISTRY, ORGANIC

Tetrahedron Letters Pub Date : 2025-06-11 DOI:10.1016/j.tetlet.2025.155710

Jian-Hao Zhou, Fei-Yun Bao, Sheng-Yin Zhao

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引用次数: 0

摘要

研究了二硫代氨基甲酸酯三乙胺盐在氯化亚铜存在下的脱硫反应。该方法为制备一系列2-氨基恶唑啉和硫脲衍生物提供了一种有效的策略。反应条件温和，官能团相容性好。通过机理研究证实了环脱硫反应的途径。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

CuCl-mediated desulfurization reactions of Dithiocarbamate Triethylamine salts: Access to 2-Aminooxazolines and Thioureas, and their synthetic applications

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CuCl-mediated desulfurization reactions of Dithiocarbamate Triethylamine salts: Access to 2-Aminooxazolines and Thioureas, and their synthetic applications

Desulfurization reactions of dithiocarbamate triethylamine salts were developed in the presence of cuprous chloride. This methodology provided an efficient strategy to prepare a series of 2-aminooxazoline and thiourea derivatives with satisfactory yields. The reaction featured mild reaction conditions and good functional group compatibilities. The pathway of cyclodesulfurization reaction was also demonstrated by mechanism studies.

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来源期刊

Tetrahedron Letters 化学-有机化学

CiteScore

3.50

自引率

5.60%

发文量

521

审稿时长

28 days

期刊介绍： Tetrahedron Letters provides maximum dissemination of outstanding developments in organic chemistry. The journal is published weekly and covers developments in techniques, structures, methods and conclusions in experimental and theoretical organic chemistry. Rapid publication of timely and significant research results enables researchers from all over the world to transmit quickly their new contributions to large, international audiences.