G V Lacasella, S De Simone, M Karaboue, A Montana, F Orsini, E Dimauro, L Cipolloni, A Cioffi, C Cecannecchia
{"title":"儿童因粪便瘤引起的胃肠道猝死:多层次法医病理学方法。","authors":"G V Lacasella, S De Simone, M Karaboue, A Montana, F Orsini, E Dimauro, L Cipolloni, A Cioffi, C Cecannecchia","doi":"10.7417/CT.2025.5221","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Sudden gastrointestinal deaths refer to unexpected fatalities that occure due severe gastrointestinal conditions. They are rare, especially when compared to sudden deaths caused by cardiovascular, respiratory or neurological events. It is even more rare that a sudden death due to gastrointestinal causes occurs in a child.</p><p><strong>Results: </strong>We presented a unique case of sudden death of a 9-year-old child with no pertinent medical history, presenting abdominal pain and diarrhea and deceased shortly after the onset of symptoms. The autopsy showed a severe intestinal obstruction due to a rectosigmoid fecaloma. In addition, the immunohistochemical evaluation revealed an inflammation of the intestine.</p><p><strong>Conclusion: </strong>In case of sudden deaths, forensic pathological investigation is essential to determine the cause of death. Diagnosis can only be made through a rigorous and multi-level post-mortem approach in which immunostochemical investigation can also make an important contribution.</p>","PeriodicalId":50686,"journal":{"name":"Clinica Terapeutica","volume":"176 3","pages":"271-277"},"PeriodicalIF":0.0000,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Sudden Gastrointestinal Deaths of a Child due to a Fecaloma: a Multilevel Forensic Pathological Approach.\",\"authors\":\"G V Lacasella, S De Simone, M Karaboue, A Montana, F Orsini, E Dimauro, L Cipolloni, A Cioffi, C Cecannecchia\",\"doi\":\"10.7417/CT.2025.5221\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Sudden gastrointestinal deaths refer to unexpected fatalities that occure due severe gastrointestinal conditions. They are rare, especially when compared to sudden deaths caused by cardiovascular, respiratory or neurological events. It is even more rare that a sudden death due to gastrointestinal causes occurs in a child.</p><p><strong>Results: </strong>We presented a unique case of sudden death of a 9-year-old child with no pertinent medical history, presenting abdominal pain and diarrhea and deceased shortly after the onset of symptoms. The autopsy showed a severe intestinal obstruction due to a rectosigmoid fecaloma. In addition, the immunohistochemical evaluation revealed an inflammation of the intestine.</p><p><strong>Conclusion: </strong>In case of sudden deaths, forensic pathological investigation is essential to determine the cause of death. Diagnosis can only be made through a rigorous and multi-level post-mortem approach in which immunostochemical investigation can also make an important contribution.</p>\",\"PeriodicalId\":50686,\"journal\":{\"name\":\"Clinica Terapeutica\",\"volume\":\"176 3\",\"pages\":\"271-277\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinica Terapeutica\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.7417/CT.2025.5221\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinica Terapeutica","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.7417/CT.2025.5221","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"Medicine","Score":null,"Total":0}
Sudden Gastrointestinal Deaths of a Child due to a Fecaloma: a Multilevel Forensic Pathological Approach.
Background: Sudden gastrointestinal deaths refer to unexpected fatalities that occure due severe gastrointestinal conditions. They are rare, especially when compared to sudden deaths caused by cardiovascular, respiratory or neurological events. It is even more rare that a sudden death due to gastrointestinal causes occurs in a child.
Results: We presented a unique case of sudden death of a 9-year-old child with no pertinent medical history, presenting abdominal pain and diarrhea and deceased shortly after the onset of symptoms. The autopsy showed a severe intestinal obstruction due to a rectosigmoid fecaloma. In addition, the immunohistochemical evaluation revealed an inflammation of the intestine.
Conclusion: In case of sudden deaths, forensic pathological investigation is essential to determine the cause of death. Diagnosis can only be made through a rigorous and multi-level post-mortem approach in which immunostochemical investigation can also make an important contribution.
期刊介绍:
La Clinica Terapeutica è una rivista di Clinica e Terapia in Medicina e Chirurgia, fondata nel 1951 dal Prof. Mariano Messini (1901-1980), Direttore dell''Istituto di Idrologia Medica dell''Università di Roma “La Sapienza”. La rivista è pubblicata come “periodico bimestrale” dalla Società Editrice Universo, casa editrice fondata nel 1945 dal Comm. Luigi Pellino. La Clinica Terapeutica è indicizzata su MEDLINE, INDEX MEDICUS, EMBASE/Excerpta Medica.