哮喘患者高强度与低强度呼吸肌训练:对呼吸肌、运动表现、呼吸困难和健康相关生活质量的影响

IF 1.3 4区 医学 Q3 ALLERGY
Journal of Asthma Pub Date : 2025-10-01 Epub Date: 2025-06-20 DOI:10.1080/02770903.2025.2519103
Cahidenur Kocak, Esra Pehlivan, Seyma Baslilar
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引用次数: 0

摘要

目的:比较高、低强度吸气肌训练(IMT)联合标准肺康复对哮喘患者呼吸肌功能、运动能力、呼吸困难及生活质量的影响。方法:将40例哮喘患者随机分为高强度IMT组(H-IMT,n = 20)和低强度IMT组(L-IMT,n = 20)。H-IMT组以最大吸气压力的80%训练,L-IMT组以最大吸气压力的30%训练,每周负荷增加5%。两组都进行了为期8周的锻炼计划,包括呼吸、强化和步行锻炼。评估干预前后患者的呼吸功能、肺功能、呼吸肌力、最大吸气和呼气压力、外周肌力、6分钟步行测试(6MWT)、改良医学研究委员会(mMRC)呼吸困难和哮喘控制测试(ACT)、哮喘生活质量问卷(AQLQ)、圣乔治呼吸生活质量问卷(SGRQ)和国际身体活动问卷(IPAQ)评分。结果:基线特征相似。两组除肺活量外,大多数结果均有改善。L-IMT组在IPAQ-SF步行(p = .03)和总分(p = .02)方面有显著提高。与L-IMT组相比,H-IMT组的mwt距离、mMRC和ACT评分明显改善。两组间比较差异无统计学意义(p < 0.05)。同样,当两组比较时,H-IMT组AQLQ-Environmental、AQLQ-Total、SGRQ-Impact、SGRQ-Total得分的改善更大。结论:两种IMT强度均可改善呼吸功能、运动能力和生活质量。高强度的IMT对哮喘控制更有效,而低强度的IMT可以增强身体活动。调整IMT强度可以优化哮喘患者的预后。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
High- vs. low-intensity inspiratory muscle training in asthma: effects on respiratory muscles, exercise performance, dyspnea, and health-related quality of life.

Objective: To compare the effects of high- and low-intensity Inspiratory Muscle Training (IMT) combined with standard pulmonary rehabilitation on respiratory muscle function, exercise capacity, dyspnea, and quality of life in asthmatic patients.

Methods: Forty asthmatic patients were randomized into high-intensity IMT (H-IMT, n = 20) and low-intensity IMT (L-IMT, n = 20) groups. The H-IMT group trained at 80% of maximal inspiratory pressure and the L-IMT group at 30%, with 5% weekly load increases. Both groups followed an 8-week exercise program including breathing, strengthening, and walking exercises. Respiratory functions, pulmonary function test, respiratory muscle strength, maximum inspiratory and expiratory pressure measurement, peripheral muscle strength, 6-min walk test (6MWT), modified Medical Research Council (mMRC) dyspnea and Asthma Control Test (ACT), Asthma Quality of Life Questionnaire (AQLQ), Saint George Respiratory Quality of Life Questionnaire (SGRQ) and International Physical Activity Questionnaire (IPAQ) scores were assessed pre- and post-intervention.

Results: Baseline characteristics were similar. Both groups improved in most outcomes except spirometric values. The L-IMT group showed significant gains in IPAQ-SF walking (p = .03) and total scores (p = .02). 6MWT distance, mMRC, and ACT scores improved significantly more in the H-IMT group compared to the L-IMT group. There was no statistically significant difference between the groups (p > 0.05). Similarly, when the groups were compared, AQLQ-Environmental, AQLQ-Total, SGRQ-Impact, SGRQ-Total scores showed more improvement in the H-IMT group.

Conclusion: Both IMT intensities improved respiratory function, exercise capacity, and quality of life. High-intensity IMT was more effective for asthma control, while low-intensity IMT enhanced physical activity. Tailoring IMT intensity may optimize outcomes for asthmatic patients.

Registration number: NCT06516848.

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来源期刊
Journal of Asthma
Journal of Asthma 医学-过敏
CiteScore
4.00
自引率
5.30%
发文量
158
审稿时长
3-8 weeks
期刊介绍: Providing an authoritative open forum on asthma and related conditions, Journal of Asthma publishes clinical research around such topics as asthma management, critical and long-term care, preventative measures, environmental counselling, and patient education.
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