{"title":"术后计算机断层灌注衍生分流分数的降低与先天性门静脉分流猫的良好预后相关。","authors":"Takahiro Nagumo, Kumiko Ishigaki, Chieko Ishikawa, Naoko Shiozawa, Kazushi Asano","doi":"10.2460/ajvr.25.04.0125","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the clinical feasibility and usefulness of CT perfusion (CTP)-derived shunt fraction (SF) for cats with congenital portosystemic shunts (PSSs) before and after surgery.</p><p><strong>Methods: </strong>All cats with PSSs were referred to our hospital for surgical treatment from April 2016 through August 2019. The shunt types were determined before surgery (first period), and SF was measured in each cat using a 320-row multidetector CT scanner. The SF was measured on postoperative days 14 (second period) and 75 (third period). The SFs were analyzed for shunt type, surgical procedure, and prognosis across all periods.</p><p><strong>Results: </strong>The study involved 8 client-owned cats with PSSs. In cats with PSSs, the SF during the third period was significantly lower than that during the first period. In cats with left gastrophrenic shunts, the SF during the third period was significantly lower than that during the first period. There was no significant difference between the periods in SF of cats with partial ligation. A significant reduction of SF was identified as a positive prognostic indicator.</p><p><strong>Conclusions: </strong>This study showed that CTP was feasible for the measurement of SF in feline PSSs.</p><p><strong>Clinical relevance: </strong>The CTP-derived SF may be useful for evaluating the surgical results of PSSs and may help reveal the pathophysiology of feline PSSs and evaluate prognosis.</p>","PeriodicalId":7754,"journal":{"name":"American journal of veterinary research","volume":" ","pages":"1-6"},"PeriodicalIF":1.3000,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Postoperative reduction in computed tomography perfusion-derived shunt fraction is associated with favorable prognosis in cats with congenital portosystemic shunt.\",\"authors\":\"Takahiro Nagumo, Kumiko Ishigaki, Chieko Ishikawa, Naoko Shiozawa, Kazushi Asano\",\"doi\":\"10.2460/ajvr.25.04.0125\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>To evaluate the clinical feasibility and usefulness of CT perfusion (CTP)-derived shunt fraction (SF) for cats with congenital portosystemic shunts (PSSs) before and after surgery.</p><p><strong>Methods: </strong>All cats with PSSs were referred to our hospital for surgical treatment from April 2016 through August 2019. The shunt types were determined before surgery (first period), and SF was measured in each cat using a 320-row multidetector CT scanner. The SF was measured on postoperative days 14 (second period) and 75 (third period). The SFs were analyzed for shunt type, surgical procedure, and prognosis across all periods.</p><p><strong>Results: </strong>The study involved 8 client-owned cats with PSSs. In cats with PSSs, the SF during the third period was significantly lower than that during the first period. In cats with left gastrophrenic shunts, the SF during the third period was significantly lower than that during the first period. There was no significant difference between the periods in SF of cats with partial ligation. A significant reduction of SF was identified as a positive prognostic indicator.</p><p><strong>Conclusions: </strong>This study showed that CTP was feasible for the measurement of SF in feline PSSs.</p><p><strong>Clinical relevance: </strong>The CTP-derived SF may be useful for evaluating the surgical results of PSSs and may help reveal the pathophysiology of feline PSSs and evaluate prognosis.</p>\",\"PeriodicalId\":7754,\"journal\":{\"name\":\"American journal of veterinary research\",\"volume\":\" \",\"pages\":\"1-6\"},\"PeriodicalIF\":1.3000,\"publicationDate\":\"2025-06-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"American journal of veterinary research\",\"FirstCategoryId\":\"97\",\"ListUrlMain\":\"https://doi.org/10.2460/ajvr.25.04.0125\",\"RegionNum\":3,\"RegionCategory\":\"农林科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"VETERINARY SCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"American journal of veterinary research","FirstCategoryId":"97","ListUrlMain":"https://doi.org/10.2460/ajvr.25.04.0125","RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"VETERINARY SCIENCES","Score":null,"Total":0}
Postoperative reduction in computed tomography perfusion-derived shunt fraction is associated with favorable prognosis in cats with congenital portosystemic shunt.
Objective: To evaluate the clinical feasibility and usefulness of CT perfusion (CTP)-derived shunt fraction (SF) for cats with congenital portosystemic shunts (PSSs) before and after surgery.
Methods: All cats with PSSs were referred to our hospital for surgical treatment from April 2016 through August 2019. The shunt types were determined before surgery (first period), and SF was measured in each cat using a 320-row multidetector CT scanner. The SF was measured on postoperative days 14 (second period) and 75 (third period). The SFs were analyzed for shunt type, surgical procedure, and prognosis across all periods.
Results: The study involved 8 client-owned cats with PSSs. In cats with PSSs, the SF during the third period was significantly lower than that during the first period. In cats with left gastrophrenic shunts, the SF during the third period was significantly lower than that during the first period. There was no significant difference between the periods in SF of cats with partial ligation. A significant reduction of SF was identified as a positive prognostic indicator.
Conclusions: This study showed that CTP was feasible for the measurement of SF in feline PSSs.
Clinical relevance: The CTP-derived SF may be useful for evaluating the surgical results of PSSs and may help reveal the pathophysiology of feline PSSs and evaluate prognosis.
期刊介绍：
The American Journal of Veterinary Research supports the collaborative exchange of information between researchers and clinicians by publishing novel research findings that bridge the gulf between basic research and clinical practice or that help to translate laboratory research and preclinical studies to the development of clinical trials and clinical practice. The journal welcomes submission of high-quality original studies and review articles in a wide range of scientific fields, including anatomy, anesthesiology, animal welfare, behavior, epidemiology, genetics, heredity, infectious disease, molecular biology, oncology, pharmacology, pathogenic mechanisms, physiology, surgery, theriogenology, toxicology, and vaccinology. Species of interest include production animals, companion animals, equids, exotic animals, birds, reptiles, and wild and marine animals. Reports of laboratory animal studies and studies involving the use of animals as experimental models of human diseases are considered only when the study results are of demonstrable benefit to the species used in the research or to another species of veterinary interest. Other fields of interest or animals species are not necessarily excluded from consideration, but such reports must focus on novel research findings. Submitted papers must make an original and substantial contribution to the veterinary medicine knowledge base; preliminary studies are not appropriate.
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