{"title":"ESMAC最佳论文2024:定义外骨骼目标问题:使用双层优化模拟具有明确目标的最佳辅助时刻","authors":"Israel Luis , Elena M. Gutierrez-Farewik","doi":"10.1016/j.gaitpost.2025.06.006","DOIUrl":null,"url":null,"abstract":"<div><h3>Introduction</h3><div>Musculoskeletal simulations can guide the search for optimal strategies to assist motion and reveal causal relationships between assistive moments and muscle dynamics. Assistive devices such as exoskeletons can complement muscle forces based on various aims, such as minimum muscle effort or maximal force distribution. In this study, we present a simulation framework to systematically identify optimal assistance, formulated as a bilevel optimization in a single inverse simulation scheme that seeks optimal assistive moments that fulfill different assistive device aims.</div></div><div><h3>Methods</h3><div>Bilevel optimization of assistive moment was structured as an inner optimization problem to solve the muscle redundancy problem nested within an outer optimization problem that executes the inner problem iteratively, seeking an assistive moment that best satisfies the assistive aim. We used this framework to predict optimal ankle plantarflexion, hip extension, hip flexion, and hip abduction assistance, for three different aims: minimal muscle activations, minimal metabolic rates, and minimal muscle moments. Experimental data from twelve participants walking at preferred speed were used in this study.</div></div><div><h3>Results</h3><div>We found that the optimal moment trajectory is unique for a given assistive aim; i.e., the assistive aim matters. Differences in the assistive trajectories are explained at the muscle level, and as active and passive force contributions to the net muscle moments and muscle mechanical work. Interestingly, the assistive moments for minimal metabolic rates predicted an assistance period and peak timing similar to those reported from experimental studies.</div></div><div><h3>Conclusions</h3><div>Our findings suggest that explicit assistive aim formulation is required to investigate human-device interaction under optimal assistance.</div></div>","PeriodicalId":12496,"journal":{"name":"Gait & posture","volume":"121 ","pages":"Pages 315-324"},"PeriodicalIF":2.2000,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"ESMAC Best Paper 2024: Defining exoskeleton aim matters: Simulating optimal assistive moments with explicit objectives using bilevel optimization\",\"authors\":\"Israel Luis , Elena M. Gutierrez-Farewik\",\"doi\":\"10.1016/j.gaitpost.2025.06.006\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Introduction</h3><div>Musculoskeletal simulations can guide the search for optimal strategies to assist motion and reveal causal relationships between assistive moments and muscle dynamics. Assistive devices such as exoskeletons can complement muscle forces based on various aims, such as minimum muscle effort or maximal force distribution. In this study, we present a simulation framework to systematically identify optimal assistance, formulated as a bilevel optimization in a single inverse simulation scheme that seeks optimal assistive moments that fulfill different assistive device aims.</div></div><div><h3>Methods</h3><div>Bilevel optimization of assistive moment was structured as an inner optimization problem to solve the muscle redundancy problem nested within an outer optimization problem that executes the inner problem iteratively, seeking an assistive moment that best satisfies the assistive aim. We used this framework to predict optimal ankle plantarflexion, hip extension, hip flexion, and hip abduction assistance, for three different aims: minimal muscle activations, minimal metabolic rates, and minimal muscle moments. Experimental data from twelve participants walking at preferred speed were used in this study.</div></div><div><h3>Results</h3><div>We found that the optimal moment trajectory is unique for a given assistive aim; i.e., the assistive aim matters. Differences in the assistive trajectories are explained at the muscle level, and as active and passive force contributions to the net muscle moments and muscle mechanical work. Interestingly, the assistive moments for minimal metabolic rates predicted an assistance period and peak timing similar to those reported from experimental studies.</div></div><div><h3>Conclusions</h3><div>Our findings suggest that explicit assistive aim formulation is required to investigate human-device interaction under optimal assistance.</div></div>\",\"PeriodicalId\":12496,\"journal\":{\"name\":\"Gait & posture\",\"volume\":\"121 \",\"pages\":\"Pages 315-324\"},\"PeriodicalIF\":2.2000,\"publicationDate\":\"2025-06-10\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Gait & posture\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0966636225002383\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"NEUROSCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Gait & posture","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0966636225002383","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"NEUROSCIENCES","Score":null,"Total":0}
ESMAC Best Paper 2024: Defining exoskeleton aim matters: Simulating optimal assistive moments with explicit objectives using bilevel optimization
Introduction
Musculoskeletal simulations can guide the search for optimal strategies to assist motion and reveal causal relationships between assistive moments and muscle dynamics. Assistive devices such as exoskeletons can complement muscle forces based on various aims, such as minimum muscle effort or maximal force distribution. In this study, we present a simulation framework to systematically identify optimal assistance, formulated as a bilevel optimization in a single inverse simulation scheme that seeks optimal assistive moments that fulfill different assistive device aims.
Methods
Bilevel optimization of assistive moment was structured as an inner optimization problem to solve the muscle redundancy problem nested within an outer optimization problem that executes the inner problem iteratively, seeking an assistive moment that best satisfies the assistive aim. We used this framework to predict optimal ankle plantarflexion, hip extension, hip flexion, and hip abduction assistance, for three different aims: minimal muscle activations, minimal metabolic rates, and minimal muscle moments. Experimental data from twelve participants walking at preferred speed were used in this study.
Results
We found that the optimal moment trajectory is unique for a given assistive aim; i.e., the assistive aim matters. Differences in the assistive trajectories are explained at the muscle level, and as active and passive force contributions to the net muscle moments and muscle mechanical work. Interestingly, the assistive moments for minimal metabolic rates predicted an assistance period and peak timing similar to those reported from experimental studies.
Conclusions
Our findings suggest that explicit assistive aim formulation is required to investigate human-device interaction under optimal assistance.
期刊介绍:
Gait & Posture is a vehicle for the publication of up-to-date basic and clinical research on all aspects of locomotion and balance.
The topics covered include: Techniques for the measurement of gait and posture, and the standardization of results presentation; Studies of normal and pathological gait; Treatment of gait and postural abnormalities; Biomechanical and theoretical approaches to gait and posture; Mathematical models of joint and muscle mechanics; Neurological and musculoskeletal function in gait and posture; The evolution of upright posture and bipedal locomotion; Adaptations of carrying loads, walking on uneven surfaces, climbing stairs etc; spinal biomechanics only if they are directly related to gait and/or posture and are of general interest to our readers; The effect of aging and development on gait and posture; Psychological and cultural aspects of gait; Patient education.