高氧恢复对低氧运动诱导的代谢适应的影响：脂质组学方法

IF 3.9 2区生物学 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY

Biochimica et biophysica acta. Molecular and cell biology of lipids Pub Date : 2025-06-14 DOI:10.1016/j.bbalip.2025.159647

Simone Serrao , Eleonora Bossi , Vanna Denti , Johannes Burtscher , Martin Faulhaber , Günter Weiss , Wolfgang Schobersberger , Tobias Dünnwald , Giuseppe Paglia

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引用次数: 0

摘要

本文研究了11名男运动员在低氧或高氧条件下进行体育锻炼时的恢复阶段对脂质代谢的影响。我们观察到，当运动员在恢复期间接受补充氧气时，血浆三酰甘油和二酰甘油会增加，同时鞘磷脂也会减少。相比之下，在低氧恢复条件下训练7天后，运动员的循环脂质没有明显变化。我们认为，低氧运动诱导了潜在的保护性代谢适应，这种适应可能被高氧恢复所破坏。

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Hyperoxic recovery impacts on metabolic adaptations induced by hypoxic exercise: A lipidomics approach

This study investigates the effect of recovery phases in either hyperoxic air or hypoxic air during physical exercise in hypoxia on lipid metabolism in 11 male athletes.

We observed a long-term effect leading to increased plasma triacylglycerols and diacylglycerols, along with a decrease in sphingomyelin when athletes received supplemental oxygen during recovery. In contrast, no significant changes in circulating lipids were detected in athletes trained under hypoxic recovery conditions after 7 days.

We propose that hypoxic exercise induced potentially protective metabolic adaptations that might be disrupted by hyperoxic recovery.

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来源期刊

Biochimica et biophysica acta. Molecular and cell biology of lipids 生物-生化与分子生物学

CiteScore

11.00

自引率

2.10%

发文量

109

审稿时长

53 days

期刊介绍： BBA Molecular and Cell Biology of Lipids publishes papers on original research dealing with novel aspects of molecular genetics related to the lipidome, the biosynthesis of lipids, the role of lipids in cells and whole organisms, the regulation of lipid metabolism and function, and lipidomics in all organisms. Manuscripts should significantly advance the understanding of the molecular mechanisms underlying biological processes in which lipids are involved. Papers detailing novel methodology must report significant biochemical, molecular, or functional insight in the area of lipids.