{"title":"[针刺阴阴真穴配合耳穴贴敷治疗原发性痛经：随机对照试验]。","authors":"Chunxia Lu, Lin Feng, Hong Luo, Jin Cui, Bo Chen","doi":"10.13703/j.0255-2930.20241205-k0001","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>To observe the clinical effect of acupuncture at <i>yinsanzhen</i> combined with auricular point sticking on primary dysmenorrhea (PDM).</p><p><strong>Methods: </strong>Sixty patients with PDM were randomly divided into an observation group and a control group, with 30 cases in each group. Patients in the observation group were treated with acupuncture at <i>yinsanzhen</i> combined with auricular point sticking. The acupuncture was given at <i>yinsanzhen</i> (Guanyuan [CV4] and bilateral Guilai [ST29], Sanyinjiao [SP6]) once daily for 5 consecutive days. Auricular point sticking was applied to gan (CO<sub>12</sub>), shen (CO<sub>10</sub>), neifenmi (CO<sub>18</sub>), etc. every other day, alternated between ears, totaling 3 sessions. All treatments were started 5 days before menstruation. Patients in the control group were treated with ibuprofen sustained-release capsules on the first day of menstruation for 3 consecutive days. Both groups were treated for 3 menstrual cycles. The scores of Cox menstrual symptom scale (CMSS) and visual analogue scale (VAS) were compared between the two groups before and after treatment and at the second menstrual cycle after treatment completion (follow-up). The serum contents of prostaglandin (PG) F2α and PGE2 were detected before and after treatment, and the clinical effect and safety of the two groups were evaluated.</p><p><strong>Results: </strong>After treatment and during follow-up, the CMSS severity and duration scores and VAS scores of the two groups were lower than those before treatment (<i>P</i><0.05 ), and the scores in the observation group were lower than those in the control group (<i>P</i><0.05). After treatment, the serum contents of PGF2α were decreased, and the contents of PGE2 were increased (<i>P</i><0.05) in the two groups. The total effective rate of the observation group was 93.3% (28/30), which was higher than 80.0% (24/30) of the control group (<i>P</i><0.05). There were no adverse reactions in both groups.</p><p><strong>Conclusion: </strong><i>Yinsanzhen</i> combined with auricular point sticking can effectively improve the pain symptoms, relieve the degree of pain and shorten the duration of pain in patients with PDM, which may play a therapeutic role by reducing the content of serum PGF2α and increasing the content of serum PGE2.</p>","PeriodicalId":69903,"journal":{"name":"中国针灸","volume":"45 6","pages":"761-765"},"PeriodicalIF":0.0000,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Acupuncture at <i>yinsanzhen</i> combined with auricular point sticking in the treatment of primary dysmenorrhea: a randomized controlled trial].\",\"authors\":\"Chunxia Lu, Lin Feng, Hong Luo, Jin Cui, Bo Chen\",\"doi\":\"10.13703/j.0255-2930.20241205-k0001\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>To observe the clinical effect of acupuncture at <i>yinsanzhen</i> combined with auricular point sticking on primary dysmenorrhea (PDM).</p><p><strong>Methods: </strong>Sixty patients with PDM were randomly divided into an observation group and a control group, with 30 cases in each group. Patients in the observation group were treated with acupuncture at <i>yinsanzhen</i> combined with auricular point sticking. The acupuncture was given at <i>yinsanzhen</i> (Guanyuan [CV4] and bilateral Guilai [ST29], Sanyinjiao [SP6]) once daily for 5 consecutive days. Auricular point sticking was applied to gan (CO<sub>12</sub>), shen (CO<sub>10</sub>), neifenmi (CO<sub>18</sub>), etc. every other day, alternated between ears, totaling 3 sessions. All treatments were started 5 days before menstruation. Patients in the control group were treated with ibuprofen sustained-release capsules on the first day of menstruation for 3 consecutive days. Both groups were treated for 3 menstrual cycles. The scores of Cox menstrual symptom scale (CMSS) and visual analogue scale (VAS) were compared between the two groups before and after treatment and at the second menstrual cycle after treatment completion (follow-up). The serum contents of prostaglandin (PG) F2α and PGE2 were detected before and after treatment, and the clinical effect and safety of the two groups were evaluated.</p><p><strong>Results: </strong>After treatment and during follow-up, the CMSS severity and duration scores and VAS scores of the two groups were lower than those before treatment (<i>P</i><0.05 ), and the scores in the observation group were lower than those in the control group (<i>P</i><0.05). After treatment, the serum contents of PGF2α were decreased, and the contents of PGE2 were increased (<i>P</i><0.05) in the two groups. The total effective rate of the observation group was 93.3% (28/30), which was higher than 80.0% (24/30) of the control group (<i>P</i><0.05). There were no adverse reactions in both groups.</p><p><strong>Conclusion: </strong><i>Yinsanzhen</i> combined with auricular point sticking can effectively improve the pain symptoms, relieve the degree of pain and shorten the duration of pain in patients with PDM, which may play a therapeutic role by reducing the content of serum PGF2α and increasing the content of serum PGE2.</p>\",\"PeriodicalId\":69903,\"journal\":{\"name\":\"中国针灸\",\"volume\":\"45 6\",\"pages\":\"761-765\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-06-12\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"中国针灸\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.13703/j.0255-2930.20241205-k0001\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/3/28 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"中国针灸","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.13703/j.0255-2930.20241205-k0001","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/3/28 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
[Acupuncture at yinsanzhen combined with auricular point sticking in the treatment of primary dysmenorrhea: a randomized controlled trial].
Objective: To observe the clinical effect of acupuncture at yinsanzhen combined with auricular point sticking on primary dysmenorrhea (PDM).
Methods: Sixty patients with PDM were randomly divided into an observation group and a control group, with 30 cases in each group. Patients in the observation group were treated with acupuncture at yinsanzhen combined with auricular point sticking. The acupuncture was given at yinsanzhen (Guanyuan [CV4] and bilateral Guilai [ST29], Sanyinjiao [SP6]) once daily for 5 consecutive days. Auricular point sticking was applied to gan (CO12), shen (CO10), neifenmi (CO18), etc. every other day, alternated between ears, totaling 3 sessions. All treatments were started 5 days before menstruation. Patients in the control group were treated with ibuprofen sustained-release capsules on the first day of menstruation for 3 consecutive days. Both groups were treated for 3 menstrual cycles. The scores of Cox menstrual symptom scale (CMSS) and visual analogue scale (VAS) were compared between the two groups before and after treatment and at the second menstrual cycle after treatment completion (follow-up). The serum contents of prostaglandin (PG) F2α and PGE2 were detected before and after treatment, and the clinical effect and safety of the two groups were evaluated.
Results: After treatment and during follow-up, the CMSS severity and duration scores and VAS scores of the two groups were lower than those before treatment (P<0.05 ), and the scores in the observation group were lower than those in the control group (P<0.05). After treatment, the serum contents of PGF2α were decreased, and the contents of PGE2 were increased (P<0.05) in the two groups. The total effective rate of the observation group was 93.3% (28/30), which was higher than 80.0% (24/30) of the control group (P<0.05). There were no adverse reactions in both groups.
Conclusion: Yinsanzhen combined with auricular point sticking can effectively improve the pain symptoms, relieve the degree of pain and shorten the duration of pain in patients with PDM, which may play a therapeutic role by reducing the content of serum PGF2α and increasing the content of serum PGE2.
期刊介绍：
Chinese Acupuncture and Moxibustion (founded in 1981, monthly) is an authoritative academic journal of acupuncture and moxibustion under the supervision of China Association for Science and Technology and co-sponsored by Chinese Acupuncture and Moxibustion Society and Institute of Acupuncture and Moxibustion of China Academy of Traditional Chinese Medicine. It is recognised as a core journal of Chinese science and technology, a core journal of Chinese language, and is included in the core journals of China Science Citation Database, as well as being included in MEDLINE and other international well-known medical index databases. The journal adheres to the tenet of ‘improving, taking into account the popularity, colourful and realistic’, and provides valuable learning and communication opportunities for the majority of acupuncture and moxibustion clinical and scientific research workers, and plays an important role in the domestic and international publicity and promotion of acupuncture and moxibustion disciplines.
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