自体肋骨移植与多孔聚乙烯植入在小体重建中的效果:荟萃分析和系统回顾。

IF 1.1 4区 医学 Q2 Dentistry
Sofia A Finestone, Liara S Ortiz-Ocasio, Arjun Shetty, Brandon Boyarsky, Stephanie Vu, Nicole A Derdzakyan, Md Sohel Rana, Gary F Rogers, Albert K Oh
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引用次数: 0

摘要

目的小耳症的耳廓重建通常包括自体肋软骨移植(ARCG)或多孔聚乙烯(PPE)植入物。虽然ARCG被认为是金标准,但个人防护用品已显示可消除供体部位发病率。本荟萃分析比较了ARCG和PPE植入物的结果。DesignA对2000年至2023年的文献进行了系统检索,确定了3463项研究。纳入了比较ARCG和PPE的队列和大型病例系列。荟萃分析使用随机效应模型计算了小脑重建结果的综合效应大小差异。主要结局指标主要结局包括感染率、框架暴露和重做程序。次要结果评估美学结果、患者满意度和生活质量。结果6项研究符合纳入标准,共3816例患者。ARCG随访30天至11年,PPE随访30天至8年。荟萃分析显示,PPE的合并感染、框架暴露和重做手术率差异分别为3.18%(95%可信区间[CI]: -2.00, 8.36%)、6.97% (95% CI: 0.07, 13.86%)和4.88% (95% CI: -3.45, 13.20%)。发现中度至显著异质性(I2 = 39%-68%)。美学结果和患者满意度各不相同,一项研究报告PPE的满意度较高(90% vs 47.1%),而一项更大的研究发现ARCG的满意度更高(95.3% vs 82.7%)。在生活质量方面没有发现显著差异。结论与ARCG相比,ppe植入物可能具有更高的感染率、框架暴露率和重做率。较差的研究质量和异质性突出了进一步研究比较这些技术的必要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Rib Autograft Versus Porous Polyethylene Implant Outcomes in Microtia Reconstruction: A Meta-Analysis and Systematic Review.

ObjectiveAuricular reconstruction for microtia typically involves autologous rib cartilage graft (ARCG) or porous polyethylene (PPE) implants. While ARCG is considered the gold standard, PPE has shown elimination of donor site morbidity. This meta-analysis compares outcomes between ARCG and PPE implants.DesignA systematic search of literature from 2000 to 2023 identified 3463 studies. Cohorts and large case series comparing ARCG to PPE were included. Meta-analysis calculated pooled effect size differences in microtia reconstruction outcomes using a random-effects model.Main Outcome MeasuresPrimary outcomes included infection rates, framework exposure, and redo procedures. Secondary outcomes assessed aesthetic results, patient satisfaction, and quality of life.ResultsEleven studies met inclusion criteria, accounting for 3816 patients. Follow-up ranged from 30 days to 11 years for ARCG and 30 days to 8 years for PPE. Meta-analysis revealed that PPE had higher pooled infection, framework exposure, and redo operation rate differences of 3.18% (95% confidence interval [CI]: -2.00, 8.36%), 6.97% (95% CI: 0.07, 13.86%), and 4.88% (95% CI: -3.45, 13.20%), respectively. Moderate-to-significant heterogeneity was found (I2 = 39%-68%). Aesthetic outcomes and patient satisfaction varied, with 1 study reporting higher satisfaction with PPE (90% vs 47.1% for ARCG), while a larger study found greater satisfaction with ARCG (95.3% vs 82.7% for PPE). No significant differences were found in quality of life.ConclusionPPE implants may be associated with higher rates of infection, framework exposure, and redo procedures compared to ARCG. Poor study quality and heterogeneity highlight the need for further research comparing these techniques.

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来源期刊
Cleft Palate-Craniofacial Journal
Cleft Palate-Craniofacial Journal DENTISTRY, ORAL SURGERY & MEDICINE-SURGERY
CiteScore
2.20
自引率
36.40%
发文量
0
审稿时长
4-8 weeks
期刊介绍: The Cleft Palate-Craniofacial Journal (CPCJ) is the premiere peer-reviewed, interdisciplinary, international journal dedicated to current research on etiology, prevention, diagnosis, and treatment in all areas pertaining to craniofacial anomalies. CPCJ reports on basic science and clinical research aimed at better elucidating the pathogenesis, pathology, and optimal methods of treatment of cleft and craniofacial anomalies. The journal strives to foster communication and cooperation among professionals from all specialties.
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