Shivani Desai DDS , Adam Tepperman DDS , Ahmed Ben Suleiman BDS, MSc , Gevik Malkhassian DDS, MSc , David Chvartszaid DDS, MSc , Jim Yuan Lai DMD, MSc, EdD , Amir Azarpazhooh DDS, MSc, PhD
{"title":"修复手术后牙髓恶化:一项病例对照研究。","authors":"Shivani Desai DDS , Adam Tepperman DDS , Ahmed Ben Suleiman BDS, MSc , Gevik Malkhassian DDS, MSc , David Chvartszaid DDS, MSc , Jim Yuan Lai DMD, MSc, EdD , Amir Azarpazhooh DDS, MSc, PhD","doi":"10.1016/j.joen.2025.06.004","DOIUrl":null,"url":null,"abstract":"<div><h3>Introduction</h3><div>While restorative procedures aim to preserve tooth structure and function, they may contribute to pulpal deterioration, potentially necessitating endodontic intervention. This matched case-control study examined the time lapse from the most recent definitive (terminal) restoration to the onset of pulpal deterioration.</div></div><div><h3>Methods</h3><div>A computerized search of dental records (1999–2023) at the University of Toronto identified 1,360 permanent teeth that received terminal restorations followed by endodontic therapy (cases), matched 1:1 with 1,360 teeth that received terminal restorations without subsequent endodontic therapy (controls). Matching criteria included age at the time of restoration, tooth type, and number of prior restorations. Data were analyzed using descriptive statistics, chi-square tests, and multivariable Cox regression.</div></div><div><h3>Results</h3><div>The median time lapse to pulpal deterioration among cases was 14.3 months. Crowns and bridge retainers had the longest interval (28 months), followed by amalgam (17.4), composite resin (11.9), and glass ionomer (11.4). Earlier deterioration was observed in teeth with restorations involving more than two surfaces (11.5), with more than 2 prior restorations (13.9), and with pulp exposure (6.6). In adjusted analyses, glass ionomer (hazard ratio = 1.6; 95% confidence interval: 1.2–2.2) and multisurface restorations (hazard ratio = 1.5; 95% confidence interval: 1.2–1.7) were statistically significant associated variables.</div></div><div><h3>Conclusions</h3><div>Pulpal deterioration may occur after a median time lapse of 14.3 months following terminal restoration placement. Crowns/bridge retainers and amalgam restorations were associated with slower progression of pulpal deterioration, whereas composite resin, glass ionomer, multisurface restorations, and pulp exposure were linked to an increased likelihood or earlier onset of pulpal deterioration.</div></div>","PeriodicalId":15703,"journal":{"name":"Journal of endodontics","volume":"51 9","pages":"Pages 1177-1186"},"PeriodicalIF":3.6000,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Pulpal Deterioration Following Restorative Procedures: A Case – Control Study\",\"authors\":\"Shivani Desai DDS , Adam Tepperman DDS , Ahmed Ben Suleiman BDS, MSc , Gevik Malkhassian DDS, MSc , David Chvartszaid DDS, MSc , Jim Yuan Lai DMD, MSc, EdD , Amir Azarpazhooh DDS, MSc, PhD\",\"doi\":\"10.1016/j.joen.2025.06.004\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Introduction</h3><div>While restorative procedures aim to preserve tooth structure and function, they may contribute to pulpal deterioration, potentially necessitating endodontic intervention. This matched case-control study examined the time lapse from the most recent definitive (terminal) restoration to the onset of pulpal deterioration.</div></div><div><h3>Methods</h3><div>A computerized search of dental records (1999–2023) at the University of Toronto identified 1,360 permanent teeth that received terminal restorations followed by endodontic therapy (cases), matched 1:1 with 1,360 teeth that received terminal restorations without subsequent endodontic therapy (controls). Matching criteria included age at the time of restoration, tooth type, and number of prior restorations. Data were analyzed using descriptive statistics, chi-square tests, and multivariable Cox regression.</div></div><div><h3>Results</h3><div>The median time lapse to pulpal deterioration among cases was 14.3 months. Crowns and bridge retainers had the longest interval (28 months), followed by amalgam (17.4), composite resin (11.9), and glass ionomer (11.4). Earlier deterioration was observed in teeth with restorations involving more than two surfaces (11.5), with more than 2 prior restorations (13.9), and with pulp exposure (6.6). In adjusted analyses, glass ionomer (hazard ratio = 1.6; 95% confidence interval: 1.2–2.2) and multisurface restorations (hazard ratio = 1.5; 95% confidence interval: 1.2–1.7) were statistically significant associated variables.</div></div><div><h3>Conclusions</h3><div>Pulpal deterioration may occur after a median time lapse of 14.3 months following terminal restoration placement. Crowns/bridge retainers and amalgam restorations were associated with slower progression of pulpal deterioration, whereas composite resin, glass ionomer, multisurface restorations, and pulp exposure were linked to an increased likelihood or earlier onset of pulpal deterioration.</div></div>\",\"PeriodicalId\":15703,\"journal\":{\"name\":\"Journal of endodontics\",\"volume\":\"51 9\",\"pages\":\"Pages 1177-1186\"},\"PeriodicalIF\":3.6000,\"publicationDate\":\"2025-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of endodontics\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0099239925003243\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"DENTISTRY, ORAL SURGERY & MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of endodontics","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0099239925003243","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"DENTISTRY, ORAL SURGERY & MEDICINE","Score":null,"Total":0}
Pulpal Deterioration Following Restorative Procedures: A Case – Control Study
Introduction
While restorative procedures aim to preserve tooth structure and function, they may contribute to pulpal deterioration, potentially necessitating endodontic intervention. This matched case-control study examined the time lapse from the most recent definitive (terminal) restoration to the onset of pulpal deterioration.
Methods
A computerized search of dental records (1999–2023) at the University of Toronto identified 1,360 permanent teeth that received terminal restorations followed by endodontic therapy (cases), matched 1:1 with 1,360 teeth that received terminal restorations without subsequent endodontic therapy (controls). Matching criteria included age at the time of restoration, tooth type, and number of prior restorations. Data were analyzed using descriptive statistics, chi-square tests, and multivariable Cox regression.
Results
The median time lapse to pulpal deterioration among cases was 14.3 months. Crowns and bridge retainers had the longest interval (28 months), followed by amalgam (17.4), composite resin (11.9), and glass ionomer (11.4). Earlier deterioration was observed in teeth with restorations involving more than two surfaces (11.5), with more than 2 prior restorations (13.9), and with pulp exposure (6.6). In adjusted analyses, glass ionomer (hazard ratio = 1.6; 95% confidence interval: 1.2–2.2) and multisurface restorations (hazard ratio = 1.5; 95% confidence interval: 1.2–1.7) were statistically significant associated variables.
Conclusions
Pulpal deterioration may occur after a median time lapse of 14.3 months following terminal restoration placement. Crowns/bridge retainers and amalgam restorations were associated with slower progression of pulpal deterioration, whereas composite resin, glass ionomer, multisurface restorations, and pulp exposure were linked to an increased likelihood or earlier onset of pulpal deterioration.
期刊介绍:
The Journal of Endodontics, the official journal of the American Association of Endodontists, publishes scientific articles, case reports and comparison studies evaluating materials and methods of pulp conservation and endodontic treatment. Endodontists and general dentists can learn about new concepts in root canal treatment and the latest advances in techniques and instrumentation in the one journal that helps them keep pace with rapid changes in this field.