基于多种机器学习算法的小学学龄儿童头前姿势障碍预测模型建立

IF 4.8 3区 工程技术 Q1 BIOTECHNOLOGY & APPLIED MICROBIOLOGY
Frontiers in Bioengineering and Biotechnology Pub Date : 2025-05-30 eCollection Date: 2025-01-01 DOI:10.3389/fbioe.2025.1607419
Hongjun Tao, Yang Wen, Rongfang Yu, Yining Xu, Fangliang Yu
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引用次数: 0

摘要

背景:头部前倾在小学生中经常发生,可能是由于长时间久坐与学业要求和体力活动减少有关。然而,现有的预防和筛查方法并不能准确、及时地预测头部前倾的发病。目的:利用最小绝对收缩和选择算子(LASSO)回归算法寻找小学生前倾头部姿势的高敏感预测指标。运用多种机器学习算法构建不同的风险预测模型,通过对比分析选择最有效的模型。Shapley加性解释(SHAP)方法用于量化每个特征对模型结果的影响,确保增强模型的可解释性。方法:采用横断面研究设计,本研究招募了520名小学学龄儿童,收集了人口统计学、人体测量学和身体活动水平的数据。采用单因素logistic回归分析确定前倾头位的高危因素。随后应用LASSO算法选择关键预测因子。开发了k近邻(KNN)、光梯度增强机(LGBM)、极端梯度增强机(XGBoost)、随机森林(RF)、线性模型(LM)和支持向量机(SVM)等6种机器学习模型来预测风险。对每个模型的性能进行评估,并使用Shapley加性解释(SHAP)算法进一步解释表现最佳的模型。结果:共有514名儿童最终被纳入研究,其中300名儿童表现出前倾的头部姿势。LASSO分析发现,年龄、体重、身体质量指数、性别和每周总作业时间是主要的风险指标。在6种预测模型中,随机森林算法表现出最高的性能(AUC = 0.865),显著优于其他预测模型。SHAP分析显示,BMI、体重和年龄是最具影响力的预测因素,其中BMI贡献最大。结论:基于随机森林的预测模型对中国小学生前向头部姿势具有较好的预测准确性,强调了监测BMI、体重和年龄对早期干预和预防的重要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Predictive model establishment for forward-head posture disorder in primary-school-aged children based on multiple machine learning algorithms.

Background: Forward head posture frequently occurs among primary school children, potentially due to prolonged sedentary behavior associated with academic demands and reduced physical activity. However, existing prevention and screening methods fail to accurately and promptly predict the onset of forward head posture.

Objective: This study aims to identify highly sensitive predictive indicators for forward head posture in primary school children using the Least Absolute Shrinkage and Selection Operator (LASSO) regression algorithm. Multiple machine learning algorithms are applied to construct distinct risk prediction models, with the most effective model selected through comparative analysis. The Shapley Additive Explanations (SHAP) method is used to quantify the influence of each feature on model outcomes, ensuring enhanced model interpretability.

Methods: Employing a cross-sectional study design, this research recruited 520 primary school-aged children, gathering data on demographics, anthropometrics, and physical activity levels. Univariate logistic regression was utilized to identify high-risk factors for forward head posture. The LASSO algorithm was subsequently applied to select key predictors. Six machine learning models-K-nearest neighbor (KNN), light gradient boosting machine (LGBM), extreme gradient boosting (XGBoost), random forest (RF), linear model (LM), and support vector machine (SVM)-were developed to predict risk. The performance of each model was evaluated, and the best-performing model was further interpreted using the Shapley Additive Explanations (SHAP) algorithm.

Results: A total of 514 children were ultimately included in the study, of whom 300 exhibited forward head posture. LASSO analysis identified age, bodyweight, BMI, sex, and weekly total homework time as prominent risk indicators. Among the 6 predictive models, the random forest algorithm demonstrated the highest performance (AUC = 0.865), significantly outperforming the others. SHAP analysis revealed that BMI, bodyweight, and age were the most influential predictors, with BMI contributing the most.

Conclusion: The random forest-based prediction model achieved superior predictive accuracy for forward head posture among Chinese primary school children, emphasizing the importance of monitoring BMI, bodyweight, and age for early intervention and prevention efforts.

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来源期刊
Frontiers in Bioengineering and Biotechnology
Frontiers in Bioengineering and Biotechnology Chemical Engineering-Bioengineering
CiteScore
8.30
自引率
5.30%
发文量
2270
审稿时长
12 weeks
期刊介绍: The translation of new discoveries in medicine to clinical routine has never been easy. During the second half of the last century, thanks to the progress in chemistry, biochemistry and pharmacology, we have seen the development and the application of a large number of drugs and devices aimed at the treatment of symptoms, blocking unwanted pathways and, in the case of infectious diseases, fighting the micro-organisms responsible. However, we are facing, today, a dramatic change in the therapeutic approach to pathologies and diseases. Indeed, the challenge of the present and the next decade is to fully restore the physiological status of the diseased organism and to completely regenerate tissue and organs when they are so seriously affected that treatments cannot be limited to the repression of symptoms or to the repair of damage. This is being made possible thanks to the major developments made in basic cell and molecular biology, including stem cell science, growth factor delivery, gene isolation and transfection, the advances in bioengineering and nanotechnology, including development of new biomaterials, biofabrication technologies and use of bioreactors, and the big improvements in diagnostic tools and imaging of cells, tissues and organs. In today`s world, an enhancement of communication between multidisciplinary experts, together with the promotion of joint projects and close collaborations among scientists, engineers, industry people, regulatory agencies and physicians are absolute requirements for the success of any attempt to develop and clinically apply a new biological therapy or an innovative device involving the collective use of biomaterials, cells and/or bioactive molecules. “Frontiers in Bioengineering and Biotechnology” aspires to be a forum for all people involved in the process by bridging the gap too often existing between a discovery in the basic sciences and its clinical application.
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