{"title":"股骨近端仿生钉三角形支撑结构与传统长髓内钉治疗转子下骨折的生物力学评价。","authors":"Yanjiang Yang, Dongwei Wu, Xiaodong Cheng, Wei He, Wei Chen, Yingze Zhang, Qi Zhang","doi":"10.3389/fbioe.2025.1579842","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this study was to compare the biomechanical results of long proximal femoral bionic nail (PFBN) and three conventional intramedullary nails in the treatment of subtrochanteric fractures (STFs).</p><p><strong>Methods: </strong>Using finite element analysis, we compared the therapeutic efficacy of four long intramedullary nails: the PFBN, reconstruction nail (RCN), InterTAN nail (ITN), and proximal femoral nail antirotation (PFNA) for the treatment of Seinsheimer type IIIA and type V STFs. The biomechanical stability of the implants was evaluated by calculating of von Mises stress (VMS), contact pressure and displacement for three loading scenarios.</p><p><strong>Results: </strong>The results showed that the PFBN group had the lowest VMS values under axial, bending and torsional loads. Under axial loading conditions, the VMS of PFBN was 480.04 MPa, followed by ITN (726.39 MPa), PFNA (730.48 MPa), and RCN (837.24 MPa) in the type V fracture groups. In the PFBN group, the contact pressure was 19.22 MPa and the tangential micromotion was 0.089 mm for the type IIIA group, 23.69 MPa and 0.08 mm for the type V group. Compared to the ITN, PFNA and RCN groups, the PFBN group exhibited the lowest contact pressure and tangential micromotion at the fracture sites.</p><p><strong>Conclusion: </strong>The superior biomechanical properties of the PFBN under axial, bending, and torsional loads not only reduced stress at the fracture site, but also improved structural stability.</p>","PeriodicalId":12444,"journal":{"name":"Frontiers in Bioengineering and Biotechnology","volume":"13 ","pages":"1579842"},"PeriodicalIF":4.3000,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12162655/pdf/","citationCount":"0","resultStr":"{\"title\":\"Biomechanical evaluation of the triangular support structure of the proximal femoral bionic nail compared to conventional long intramedullary nails for subtrochanteric fractures.\",\"authors\":\"Yanjiang Yang, Dongwei Wu, Xiaodong Cheng, Wei He, Wei Chen, Yingze Zhang, Qi Zhang\",\"doi\":\"10.3389/fbioe.2025.1579842\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>The aim of this study was to compare the biomechanical results of long proximal femoral bionic nail (PFBN) and three conventional intramedullary nails in the treatment of subtrochanteric fractures (STFs).</p><p><strong>Methods: </strong>Using finite element analysis, we compared the therapeutic efficacy of four long intramedullary nails: the PFBN, reconstruction nail (RCN), InterTAN nail (ITN), and proximal femoral nail antirotation (PFNA) for the treatment of Seinsheimer type IIIA and type V STFs. The biomechanical stability of the implants was evaluated by calculating of von Mises stress (VMS), contact pressure and displacement for three loading scenarios.</p><p><strong>Results: </strong>The results showed that the PFBN group had the lowest VMS values under axial, bending and torsional loads. Under axial loading conditions, the VMS of PFBN was 480.04 MPa, followed by ITN (726.39 MPa), PFNA (730.48 MPa), and RCN (837.24 MPa) in the type V fracture groups. In the PFBN group, the contact pressure was 19.22 MPa and the tangential micromotion was 0.089 mm for the type IIIA group, 23.69 MPa and 0.08 mm for the type V group. Compared to the ITN, PFNA and RCN groups, the PFBN group exhibited the lowest contact pressure and tangential micromotion at the fracture sites.</p><p><strong>Conclusion: </strong>The superior biomechanical properties of the PFBN under axial, bending, and torsional loads not only reduced stress at the fracture site, but also improved structural stability.</p>\",\"PeriodicalId\":12444,\"journal\":{\"name\":\"Frontiers in Bioengineering and Biotechnology\",\"volume\":\"13 \",\"pages\":\"1579842\"},\"PeriodicalIF\":4.3000,\"publicationDate\":\"2025-05-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12162655/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Frontiers in Bioengineering and Biotechnology\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://doi.org/10.3389/fbioe.2025.1579842\",\"RegionNum\":3,\"RegionCategory\":\"工程技术\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q1\",\"JCRName\":\"BIOTECHNOLOGY & APPLIED MICROBIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Frontiers in Bioengineering and Biotechnology","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.3389/fbioe.2025.1579842","RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q1","JCRName":"BIOTECHNOLOGY & APPLIED MICROBIOLOGY","Score":null,"Total":0}
Biomechanical evaluation of the triangular support structure of the proximal femoral bionic nail compared to conventional long intramedullary nails for subtrochanteric fractures.
Purpose: The aim of this study was to compare the biomechanical results of long proximal femoral bionic nail (PFBN) and three conventional intramedullary nails in the treatment of subtrochanteric fractures (STFs).
Methods: Using finite element analysis, we compared the therapeutic efficacy of four long intramedullary nails: the PFBN, reconstruction nail (RCN), InterTAN nail (ITN), and proximal femoral nail antirotation (PFNA) for the treatment of Seinsheimer type IIIA and type V STFs. The biomechanical stability of the implants was evaluated by calculating of von Mises stress (VMS), contact pressure and displacement for three loading scenarios.
Results: The results showed that the PFBN group had the lowest VMS values under axial, bending and torsional loads. Under axial loading conditions, the VMS of PFBN was 480.04 MPa, followed by ITN (726.39 MPa), PFNA (730.48 MPa), and RCN (837.24 MPa) in the type V fracture groups. In the PFBN group, the contact pressure was 19.22 MPa and the tangential micromotion was 0.089 mm for the type IIIA group, 23.69 MPa and 0.08 mm for the type V group. Compared to the ITN, PFNA and RCN groups, the PFBN group exhibited the lowest contact pressure and tangential micromotion at the fracture sites.
Conclusion: The superior biomechanical properties of the PFBN under axial, bending, and torsional loads not only reduced stress at the fracture site, but also improved structural stability.
期刊介绍：
The translation of new discoveries in medicine to clinical routine has never been easy. During the second half of the last century, thanks to the progress in chemistry, biochemistry and pharmacology, we have seen the development and the application of a large number of drugs and devices aimed at the treatment of symptoms, blocking unwanted pathways and, in the case of infectious diseases, fighting the micro-organisms responsible. However, we are facing, today, a dramatic change in the therapeutic approach to pathologies and diseases. Indeed, the challenge of the present and the next decade is to fully restore the physiological status of the diseased organism and to completely regenerate tissue and organs when they are so seriously affected that treatments cannot be limited to the repression of symptoms or to the repair of damage. This is being made possible thanks to the major developments made in basic cell and molecular biology, including stem cell science, growth factor delivery, gene isolation and transfection, the advances in bioengineering and nanotechnology, including development of new biomaterials, biofabrication technologies and use of bioreactors, and the big improvements in diagnostic tools and imaging of cells, tissues and organs.
In today`s world, an enhancement of communication between multidisciplinary experts, together with the promotion of joint projects and close collaborations among scientists, engineers, industry people, regulatory agencies and physicians are absolute requirements for the success of any attempt to develop and clinically apply a new biological therapy or an innovative device involving the collective use of biomaterials, cells and/or bioactive molecules. “Frontiers in Bioengineering and Biotechnology” aspires to be a forum for all people involved in the process by bridging the gap too often existing between a discovery in the basic sciences and its clinical application.
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