基于nsfet的全门树形生物传感器:一种高灵敏度的无标记生物分子检测方法

IF 7.9 Q1 ENGINEERING, MULTIDISCIPLINARY
U. Gowthami , M. Durga Prakash , B.V.V. Satyanarayana , G. Prasanna Kumar , Asisa Kumar Panigrahy , Amit Krishna Dwivedi
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引用次数: 0

摘要

本文提出并研究了一种采用栅极树形纳米片场效应晶体管(GAA-TS-NSFET)的无标签介质调制生物传感器。当在各种生物分子影响下评估时,所建议的生物传感器的电学特性证明了对带电和中性生物分子的优异敏感性。对具有不同通道配置的生物传感器的传感能力进行了全面的灵敏度评估。作为生物传感器灵敏度变化的指标,我们研究了亚阈值摆幅(SS)、阈值电压(Vth)和电流开关比(Ion/Ioff)。根据研究结果,与基于nsfet的生物传感器相比,一个额外的通道充当了一个桥梁,使树形生物传感器获得了最佳的灵敏度。此外,本文还研究了不同垫片材料对灵敏度的影响。我们还运行了几个场景,看看不同的填充百分比如何影响所建议的生物传感器的灵敏度。存在的生物分子的数量决定了它的灵敏度。最后,在状态图中比较了建议的生物传感器的灵敏度与其他显着的生物传感器应用成果。本文提出的基于gaa - ts - nsfet的生物传感器在离子/ off灵敏度方面优于以往的工作。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Gate-all-around tree-shaped NSFET-based biosensor: A high-sensitivity approach for label-free biomolecule detection
This paper proposes and investigates a label-free dielectrically modulated biosensor employing a Gate All Around Tree-Shaped Nanosheet Field Effect Transistor (GAA-TS-NSFET). Excellent sensitivity to the biomolecules which are charged and neutral are demonstrated by the electrical properties of the suggested biosensor when evaluated under various biomolecule influences. A thorough sensitivity assessment is used to assess the sensing capabilities of the biosensors with various channel configurations. As indicators of biosensor sensitivity variation, we examine the subthreshold swing (SS), threshold voltage (Vth), and current switching ratio (Ion/Ioff). According to the findings, an additional channel acts as an interbridge, allowing the tree-shaped biosensor to attain the best sensitivity compared to biosensors based on NSFETs. Additionally, the article investigates how various spacer materials impact sensitivity. We also run several scenarios to see how different fill percentages affect the proposed biosensor’s sensitivity. The amount of biomolecules present determines its sensitivity. Finally, the suggested biosensor's sensitivity is compared to other notable biosensing application efforts in a status map. The proposed GAA-TS-NSFET-based biosensor outperforms the previous works concerning Ion/Ioff sensitivity.
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来源期刊
Results in Engineering
Results in Engineering Engineering-Engineering (all)
CiteScore
5.80
自引率
34.00%
发文量
441
审稿时长
47 days
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