促进采用最佳做法和标准,以提高干细胞研究的质量和可重复性。

IF 5.9 2区 医学 Q1 CELL & TISSUE ENGINEERING
Stem Cell Reports Pub Date : 2025-07-08 Epub Date: 2025-06-12 DOI:10.1016/j.stemcr.2025.102531
Lucia Selfa Aspiroz, Milena Mennecozzi, Laura Batlle, Barbara Corneo, Lyn Healy, Mark Kotter, Andreas Kurtz, Tenneille E Ludwig, Christine Mummery, Martin Pera, Glyn N Stacey, Carlos A Tristan, Maurice Whelan
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引用次数: 0

摘要

推进人类干细胞模型在临床前和监管测试领域的应用,需要进行严格和可重复的研究。应促进质量标准和报告最佳做法,以确保干细胞模型和结果的可靠性和可翻译性。提高对最佳做法和标准的认识和实施的战略将需要相关利益攸关方之间的培训举措和协作。总的来说,通过最佳实践和标准来提高基于干细胞的模型和方法的质量和可重复性,将加速它们在工业和监管环境中的采用,并最终推动有效疗法和更安全化学品的发展。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Promoting the adoption of best practices and standards to enhance quality and reproducibility of stem cell research.

Advancing the use of human stem cell-based models on preclinical and regulatory testing fields requires the performance of rigorous and reproducible research. Quality standards and reporting best practices should be promoted to ensure the reliability and translatability of stem cell models and results. Strategies to increase awareness and implementation of best practices and standards will require training initiatives and collaboration across relevant stakeholders. Overall, improving the quality and reproducibility of stem cell-based models and methods through best practices and standards will accelerate their adoption in industrial and regulatory contexts and ultimately drive the development of effective therapies and safer chemicals.

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来源期刊
Stem Cell Reports
Stem Cell Reports CELL & TISSUE ENGINEERING-CELL BIOLOGY
CiteScore
10.50
自引率
1.70%
发文量
200
审稿时长
28 weeks
期刊介绍: Stem Cell Reports publishes high-quality, peer-reviewed research presenting conceptual or practical advances across the breadth of stem cell research and its applications to medicine. Our particular focus on shorter, single-point articles, timely publication, strong editorial decision-making and scientific input by leaders in the field and a "scoop protection" mechanism are reasons to submit your best papers.
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