沙特阿拉伯利雅得一家三级医院抗生素预防适宜性、持续时间和相关费用对手术部位感染率的影响:一项回顾性研究。

IF 1.5 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL
Amal Bin Akresh, Deema S Alzeet, Njoud Z Alshalan, Marwa M Alhawsawi, Nada A Alsaleh, Reem A Binsuwaidan, Alaa A Alhubaishi, Abdulaziz I Altowaijri, Najla N Alebedah, Nisreen M Sherbeeni, Lina I Alnajjar
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引用次数: 0

摘要

目的:评估外科手术部位感染(ssi)的发生率,基于手术抗生素方案的依从性和手术抗生素预防(SAP)的持续时间。次要目标包括评估30天再住院率、30天死亡率、抗生素相关不良事件,以及接受长疗程抗生素的患者延长抗生素使用的估计额外费用。方法:本回顾性观察研究于2021 - 2022年在苏丹王子军事医疗城进行。它包括接受选择性手术并接受抗生素预防的成年患者。根据SAP依从性和预防持续时间将患者分为4组。利用电子病历数据,我们分析了SAP的适宜性和持续时间与ssi发生率之间的关系。结果:共纳入375例患者,其中3%在30天内发生ssi, 8%在同一时间内需要再次住院。两组间SSI发生率(p=0.352)和再住院率(p=0.051)无统计学差异。患者使用抗生素超过24小时的直接用药费用总计7949.54沙特里亚尔(SAR),额外的出院费用为2573.65沙特里亚尔。结论:延长抗生素预防超过24小时并不能降低ssi的风险,并导致不必要的额外费用,强调了遵守既定指南的必要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The impact of antibiotic prophylaxis appropriateness, duration and associated cost on the rate of surgical site infection at a tertiary hospital in Riyadh, Saudi Arabia: A retrospective study.

Objectives: To evaluate the incidence of surgical site infections (SSIs) based on compliance with surgical antibiotic protocols and the duration of surgical antibiotic prophylaxis (SAP). Secondary objectives include assessing 30-day rehospitalization rates, 30-day mortality, antibiotic-associated adverse events, and the estimated additional costs of prolonged antibiotic use in patients receiving long courses of antibiotics.

Methods: This retrospective observational study was conducted at Prince Sultan Military Medical City from 2021 to 2022. It included adult patients who underwent elective surgery and received antibiotic prophylaxis. Patients were divided into 4 groups based on SAP compliance and prophylaxis duration. Using data from electronic medical records, we analyzed the relationship between the appropriateness and duration of SAP and the incidence of SSIs.

Results: A total of 375 patients were included, with 3% developing SSIs within 30 days and 8% requiring rehospitalization within the same period. No statistically significant differences were observed between groups regarding SSI incidence (p=0.352) or rehospitalization rates (p=0.051). The direct medication costs for patients receiving antibiotics for more than 24 hours totaled 7949.54 Saudi Riyal (SAR), with additional discharge costs of 2573.65 SAR.

Conclusion: Extending antibiotic prophylaxis beyond 24 hours did not reduce the risk of SSIs and resulted in unnecessary additional costs, highlighting the need for adherence to established guidelines.

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来源期刊
Saudi Medical Journal
Saudi Medical Journal 医学-医学:内科
CiteScore
2.30
自引率
6.20%
发文量
203
审稿时长
12 months
期刊介绍: The Saudi Medical Journal is a monthly peer-reviewed medical journal. It is an open access journal, with content released under a Creative Commons attribution-noncommercial license. The journal publishes original research articles, review articles, Systematic Reviews, Case Reports, Brief Communication, Brief Report, Clinical Note, Clinical Image, Editorials, Book Reviews, Correspondence, and Student Corner.
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