在至少10年的随访中,确定改良Harris髋关节评分和无关节炎髋关节镜治疗股髋臼撞击的临床重要结果

Emily Berzolla, Larry Chen, Griffith G. Gosnell, Nathaniel Mercer, Julian Seidenberg, Daniel J. Kaplan, Thomas Youm
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Methods: A retrospective cohort study including all patients who underwent primary HA for FAI with a single surgeon from February 2010 to December 2013 was performed. Patient outcomes were assessed with an anchor question, mHHS, and NAHS at baseline and at 1, 5, and 10 years of follow-up. MCID was calculated using the distribution-based method at all time points, using 0.5 standard deviations as the threshold. The anchor-based MCID, PASS, and SCB were calculated at 10 years using thresholds representing the optimal cutoff on a receiver operating characteristic curve. Correlations between baseline characteristics and achievement of the MCID, PASS, and SCB were assessed with binomial logistic regressions. Results: The 154 patients included in the study had a mean age of 38.8 ± 13.0 years, a mean body mass index of 24.6 ± 3.9 kg/m <jats:sup>2</jats:sup> , and 63.6% were female. The distribution-based MCID values for 1-year, 5-year, and 10-year scores were 7.8, 8.3, and 9.5 for mHHS and 9.5, 10.4, and 10.2 for NAHS, respectively. The anchor-based MCID was 20.3 for mHHS and 24.4 for NAHS. The PASS was 81.9 for mHHS and 83.1 for NAHS. The SCB values were 34.0 and 41.9 for mHHS and NAHS, respectively. Increased body mass index was associated with decreased achievement of SCB for mHHS ( <jats:italic>P</jats:italic> = .03) and NAHS ( <jats:italic>P</jats:italic> = .04), as well as NAHS PASS ( <jats:italic>P</jats:italic> = .01) and anchor-based MCID ( <jats:italic>P</jats:italic> = .01). Conclusion: The establishment of the MCID, SCB, and PASS for the NAHS and mHHS provides a valuable clinical context for improvements in outcome scores after HA. 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引用次数: 0

摘要

背景:最小临床重要差异(MCID)、患者可接受症状状态(PASS)和实质性临床获益(SCB)是有价值的临床阈值,用于提供患者结局评分的临床相关性。在股骨髋臼撞击(FAI)综合征的髋关节镜检查(HA)中,这些值已被定义为术后短期和中期,但尚未建立有意义的长期阈值。目的:对因FAI综合征接受HA治疗的患者进行至少10年的随访,确定改良Harris髋关节评分(mHHS)和非关节炎髋关节评分(NAHS)的MCID、PASS和SCB。研究设计:病例系列;证据等级,4级。方法:回顾性队列研究,包括2010年2月至2013年12月由一名外科医生接受原发性HA治疗的所有FAI患者。在基线、1年、5年和10年随访时,通过锚定问题、mHHS和NAHS评估患者结局。在所有时间点采用基于分布的方法计算MCID,以0.5个标准差为阈值。基于锚定的MCID、PASS和SCB在10年内计算,使用代表接收者工作特性曲线上最佳截止的阈值。基线特征与MCID、PASS和SCB的实现之间的相关性通过二项logistic回归进行评估。结果:154例患者平均年龄38.8±13.0岁,平均体重指数24.6±3.9 kg/ m2,女性占63.6%。基于分布的mHHS 1年、5年和10年评分的MCID值分别为7.8、8.3和9.5,NAHS为9.5、10.4和10.2。基于锚定的MCID mHHS为20.3,NAHS为24.4。mHHS的PASS为81.9,NAHS的PASS为83.1。mHHS和NAHS的SCB值分别为34.0和41.9。体重指数的增加与mHHS (P = 0.03)和NAHS (P = 0.04)、NAHS PASS (P = 0.01)和基于锚定的MCID (P = 0.01)的SCB完成率降低相关。结论:NAHS和mHHS的MCID、SCB和PASS的建立为改善HA后的预后评分提供了有价值的临床背景。基于锚点的计算始终高于基于分布的计算。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Defining Clinically Important Outcomes for the Modified Harris Hip Score and Nonarthritic Hip Scope for Hip Arthroscopy to Treat Femoroacetabular Impingement at a Minimum 10-Year Follow-up
Background: The minimal clinically important difference (MCID), Patient Acceptable Symptom State (PASS), and substantial clinical benefit (SCB) are valuable clinical thresholds used to provide clinical relevance to patient outcome scores. In hip arthroscopy (HA) for femoroacetabular impingement (FAI) syndrome, these values have been defined for the short- and midterm postoperative period, but meaningful long-term thresholds have not been established. Purpose: To define the MCID, PASS, and SCB for the modified Harris Hip Score (mHHS) and Nonarthritic Hip Score (NAHS) at a minimum follow-up of 10 years for patients who underwent HA for FAI syndrome. Study Design: Case series; Level of evidence, 4. Methods: A retrospective cohort study including all patients who underwent primary HA for FAI with a single surgeon from February 2010 to December 2013 was performed. Patient outcomes were assessed with an anchor question, mHHS, and NAHS at baseline and at 1, 5, and 10 years of follow-up. MCID was calculated using the distribution-based method at all time points, using 0.5 standard deviations as the threshold. The anchor-based MCID, PASS, and SCB were calculated at 10 years using thresholds representing the optimal cutoff on a receiver operating characteristic curve. Correlations between baseline characteristics and achievement of the MCID, PASS, and SCB were assessed with binomial logistic regressions. Results: The 154 patients included in the study had a mean age of 38.8 ± 13.0 years, a mean body mass index of 24.6 ± 3.9 kg/m 2 , and 63.6% were female. The distribution-based MCID values for 1-year, 5-year, and 10-year scores were 7.8, 8.3, and 9.5 for mHHS and 9.5, 10.4, and 10.2 for NAHS, respectively. The anchor-based MCID was 20.3 for mHHS and 24.4 for NAHS. The PASS was 81.9 for mHHS and 83.1 for NAHS. The SCB values were 34.0 and 41.9 for mHHS and NAHS, respectively. Increased body mass index was associated with decreased achievement of SCB for mHHS ( P = .03) and NAHS ( P = .04), as well as NAHS PASS ( P = .01) and anchor-based MCID ( P = .01). Conclusion: The establishment of the MCID, SCB, and PASS for the NAHS and mHHS provides a valuable clinical context for improvements in outcome scores after HA. Anchor-based calculations were consistently higher than distribution-based calculations.
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