多普勒OCT验证脉动诱导的人视网膜各向异性血管腔动力学。

IF 3.1 2区物理与天体物理 Q2 OPTICS

Optics letters Pub Date : 2025-06-15 DOI:10.1364/OL.555324

Tobiloba Adejumo, Taeyoon Son, Guangying Ma, Mojtaba Rahimi, Albert Dadzie, Jie Ding, Xincheng Yao

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引用次数: 0

摘要

本研究证实了人类视网膜血管的各向异性脉动。多普勒光学相干断层扫描（OCT）用于动态监测乳头周围血管管腔动力学。定量分析一致显示轴向腔比侧向腔变化更大，轴向与侧向腔的脉动变化率为1.26±0.08。这些发现突出了视网膜组织的各向异性生物力学特性，这有助于方向依赖性血管动力学。各向异性血管生物力学的定量评估为改善与眼部疾病相关的血管改变的检测提供了有希望的见解。

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Doppler OCT verifies pulsation-induced anisotropic vessel lumen dynamics in the human retina.

This study verifies anisotropic vessel pulsatility in human retinas. Doppler optical coherence tomography (OCT) was utilized for dynamic monitoring of peripapillary vessel lumen dynamics. Quantitative analysis consistently revealed larger axial compared to lateral lumen changes, with an axial-to-lateral pulsation change ratio of 1.26 ± 0.08. These findings highlight the anisotropic biomechanical properties of retinal tissues, which contribute to direction-dependent vascular dynamics. Quantitative assessment of anisotropic vascular biomechanics offers promising insights for improving the detection of vascular alterations associated with ocular conditions.

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来源期刊

Optics letters 物理-光学

CiteScore

6.60

自引率

8.30%

发文量

2275

审稿时长

1.7 months

期刊介绍： The Optical Society (OSA) publishes high-quality, peer-reviewed articles in its portfolio of journals, which serve the full breadth of the optics and photonics community. Optics Letters offers rapid dissemination of new results in all areas of optics with short, original, peer-reviewed communications. Optics Letters covers the latest research in optical science, including optical measurements, optical components and devices, atmospheric optics, biomedical optics, Fourier optics, integrated optics, optical processing, optoelectronics, lasers, nonlinear optics, optical storage and holography, optical coherence, polarization, quantum electronics, ultrafast optical phenomena, photonic crystals, and fiber optics. Criteria used in determining acceptability of contributions include newsworthiness to a substantial part of the optics community and the effect of rapid publication on the research of others. This journal, published twice each month, is where readers look for the latest discoveries in optics.